Mitogenic signal of epidermal growth factor in chick embryo hepatocytes: Role of PKCα

Cellular Physiology and Biochemistry

Volumn 10, Issue 4, 2000, Pages 209-218

  Mele, Raffaella ^a   Marino, Maria ^a,b   Spagnuolo, Silvana ^a   Figliola, Rocco ^a   Mangiantini, Maria Teresa ^a   Lioni, Silvia ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

Author keywords

Chick embryo hepatocytes; EGF; Mitogenic signal; PKC

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ARACHIDONIC ACID; CELL DNA; DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; ISOENZYME; MEPACRINE; MYRISTIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN E2; PROTEIN KINASE C;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL PROLIFERATION; CHICK EMBRYO; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; EMBRYO; LIVER CELL; LONG TERM EXPOSURE; MITOGENESIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0033645532     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000016352     Document Type: Article

References (37)

1. Epidermal Growth Factor
2. Regulation of inositol phospholipid-specific phospholipase C isoenzymes
3. EGF increases sn-1,2-diacylglycerol levels and activates phospholipase-D catalysed phosphatidil-coline breakdown in Swiss 3T3 cells in absence of inositol-lipid hydrolysis
4. Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29) Cellular Signalling
5. Differential translocation of protein kinase C isozymes by phorbol esters, EGF, and ANG II in rat liver WB cells
6. Epidermal growth factor counteracts insulin-induced expression of glucokinase in hepatocytes
7. Epidermal growth factor and 12-O- tetradecanoylphorbol-13-acetate stimulate lactate production and the pentose phosphate pathways in the freshly isolated rat hepatocytes
8. EGF inhibits phosphoenolpiruvate carboxykinase gene expression in rat hepatocytes in primary culture
9. Control of glycolysis in cultured chick embryo hepatocytes
10. Phorbol esters, but not EGF or insulin rapidly decrease soluble PKC activity in rat hepatocytes
11. The epidermal growth factor mitogenic signal is modulated by protein kinase C in T51b rat liver cells
12. Possible contribution of protein kinase C activation to priming for DNA synthesis induced by epidermal growth factor with insulin and its inhibition by plasma membrane in primary cultured rat hepatocytes
13. Pekala PH. Protein kinase C isoform expression during the differentiation of 3T3-L1 preadipocytes: Loss of protein kinase C-alpha isoform correlates with loss of phorbol 12-myristate 13-acetate activation of nuclear factor kappa B and acquisition of the adipocyte phenotype
14. A mutant protein kinase C that can transform fibroblasts
15. Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines
16. Constitutive presence of a catalytic fragment of protein kinase C in a small cell lung carcinoma cell line
17. V, Piccinni F: Protein kinase C isozyme pattern in liver hyperplasia
18. Heterogeneous activation of protein kinase C during rat liver regeneration
19. Distinct function of protein kinase C alpha and protein kinase beta during retinoic induced differentiation of F9
20. Involvement of protein kinase C epsilon in the stimulation of anionic amino acid transport in cultured human fibroblasts
21. Potentiation of insulin-induced phosphatidylinositol-3 kinase activity by phorbol ester is mediated by protein kinase ε
22. Overexpression of PKC epsilon in R6 fibroblasts causes increased production of active TGF beta
23. Modulation of proliferative activity and amino acid transport in chick embryo hepatocytes by EGF and retinoic acid
24. Three distinct forms of rat brain protein kinase C: Differential response to unsaturated fatty acids
25. A potential second messenger role for unsaturated fatty acids activation of Ca2+-dependent protein kinase
26. An improved non perfusive method for the isolation and purification of fetal and neonatal hepatocytes
27. Control of DNA synthesis and ornithine decarboxilase activity by hormones and acids in primary cultures of adult rat hepatocytes
28. Protein kinase Ca is necessary for erythropoietines up-regulation of c-myc and for factor-dependent DNA synthesis. Evidence for discrete signals for growth and differentiation
29. A rapid method of total lipid extraction and purification
30. Epidermal growth factor regulates aminoacid transport in chick embryo hepatocytes via protein kinase C
31. A comparative study of the hepatic MAPK and Jun NH2 terminal kinase pathways in the late gestation fetal rat
32. Different signal transduction by epidermal growth factor may be responsible for the difference in the modulation of aminoacid transport between fetal and adult hepatocytes
33. Extracellular signal-regulated kinases: ERKs in progress
34. Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation
35. Pertussis toxin-sensitive Gi involvement in epidermal growth factor-induced activation of phospholipase Cγ in rat hepatocytes
36. Regulation of proliferation of primary rat hepatocytes by eicosanoids
37. Differential activation of protein kinase Cα is associated with arachidonate release in Madin-Darby canine kidney cells