Block of the α9 nicotinic receptor by ototoxic aminoglycosides

Neuropharmacology

Volumn 39, Issue 13, 2000, Pages 2525-2532

  Rothlin, Carla V ^a   Katz, Eleonora ^a   Verbitsky, Miguel ^a   Vetter, Douglas E ^b   Heinemann, Stephen F ^b   Elgoyhen, A Belén ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Aminoglycosides; Hair cells; Nicotinic receptors; Ototoxicity

Indexed keywords

ACETYLCHOLINE; AMIKACIN; AMINOGLYCOSIDE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; KANAMYCIN; NEOMYCIN; NICOTINIC RECEPTOR; STREPTOMYCIN; 1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; ANTIINFECTIVE AGENT; CALCIUM; CHELATING AGENT; CHRNA9 PROTEIN, RAT; DRUG DERIVATIVE; EGTAZIC ACID; NICOTINIC RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CORTI ORGAN; DRUG POTENCY; DRUG RECEPTOR BINDING; HAIR CELL; NONHUMAN; OOCYTE; OTOTOXICITY; PRIORITY JOURNAL; RECEPTOR BLOCKING; XENOPUS LAEVIS; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; HEARING DISORDER; METABOLISM; OLIVARY NUCLEUS; RAT; XENOPUS;

ANIMALS; ANTI-BACTERIAL AGENTS; CALCIUM; CHELATING AGENTS; EGTAZIC ACID; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; GENTAMICINS; HEARING DISORDERS; NICOTINIC ANTAGONISTS; OLIVARY NUCLEUS; OOCYTES; RATS; RECEPTORS, NICOTINIC; XENOPUS;

EID: 0033626557     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00056-3     Document Type: Article

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