Expression of mictochondrial thioredoxin-dependent antioxidant protein, SP-22, in normal human and inflammatory mouse placentae

Placenta

Volumn 21, Issue 8, 2000, Pages 847-852

  Ejima, K ^a   Nanri, H ^a   Araki, M ^a   Koji, T ^b   Shibata, E ^a   Kashimura, M ^a   Ikeda, M ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; PROTEIN; THIOREDOXIN; THIOREDOXIN DEPENDENT ANTIOXIDANT PROTEIN; UNCLASSIFIED DRUG; PEROXIDASE; PEROXIREDOXIN 3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTROPHOBLAST; DECIDUA; DIPLOIDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MITOCHONDRION; MOUSE; NONHUMAN; PLACENTA; PLACENTA DISORDER; PLACENTA VILLUS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; STROMA CELL; SYNCYTIOTROPHOBLAST; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; GESTATIONAL AGE; INFLAMMATION; METABOLISM; PREGNANCY; TROPHOBLAST; ULTRASTRUCTURE;

ANIMALS; BLOTTING, WESTERN; DECIDUA; FEMALE; GESTATIONAL AGE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MITOCHONDRIA; PEROXIDASES; PLACENTA; PLACENTA DISEASES; PREGNANCY; STROMAL CELLS; TROPHOBLASTS;

EID: 0033625976     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.2000.0569     Document Type: Article

References (26)

1. Antioxidant function of the mitochondrial protein SP-22 in the cardiovascular system
2. Lactate dehydrogenase
3. The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase
4. Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols
5. Thioredoxin-dependent peroxide reductase from yeast
6. Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall
7. Localization of thioredoxin reductase and thioredoxin in normal human placenta and their protective effect against oxidative stress
8. Expression of thioredoxin and thioredoxin reductase in placentae of pregnant mice exposed to lipopolysaccharide
9. Induction of apoptosis in placentas of pregnant mice exposed to lipopolysaccharides: Possible involvement of Fas/Fas ligand system
10. Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-a and lipopolysaccharide
11. Thioredoxin regenerates proteins inactivated by oxidative stress in endothelial cells
12. Glutathione peroxidase
13. Fumarase deficiency is an autosomal recessive encephalopathy affecting both the mitochondrial and the cytosolic enzymes
14. Interleukin-8 release from human gestational tissue explants: The effects of lipopolysaccharide and cytokines
15. Rat liver thioredoxin and thioredoxin reductase: Purification and characterization
16. Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophills or hydrogen peroxide
17. Constitutive and induced cytokine production by human placenta and amniotic membrane at term
18. Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells
19. Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes
20. Placental mitochondria as a source of oxidative stress in pre-eclampsia
21. ATP-dependent protease in bovine adrenal cortex. Tissue specificity, subcellular localization and partial characterization
22. SP-22 is a thioredoxin-dependent peroxide reductase in mitochondria
23. Susceptibility of human placental syncytiotrophoblastic mitochondria to oxygen-mediated damage in relation to gestational age
24. Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide
25. Possible differences in the regenerative roles played by thioltransferase and thioredoxin for oxidatively damaged proteins
26. Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2