Effect of oxiplex* films (PEO/CMC) on adhesion formation and reformation in rabbit models and on peritoneal infection in a rat model

Fertility and Sterility

Volumn 73, Issue 4, 2000, Pages 831-838

  Rodgers, Kathleen E ^a,b   Schwartz, Herbert E ^c   Roda, Norma ^a   Thornton, Melvin ^b   Kobak, William ^a,b   Dizerega, Gere S ^a,b  

^a Livingston Research Center   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c FzioMed Inc   (United States)

Author keywords

Adhesion; Barrier; Carboxymethylcellulose; Oxide; Polyethylene

Indexed keywords

CARBOXYMETHYLCELLULOSE; MACROGOL; BIOMATERIAL; CELLULOSE; DRUG DERIVATIVE; MACROGOL DERIVATIVE; OXIPLEX;

ABDOMEN; ADHESION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL PERITONITIS; BIOCOMPATIBILITY; CONTROLLED STUDY; FEMALE; FILM; LAPAROTOMY; MOLECULAR WEIGHT; NONHUMAN; PELVIS; PERITONEAL CAVITY; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; RABBIT; RAT; SWINE; TENSILE STRENGTH; TREATMENT OUTCOME; ANIMAL; BIODEGRADABLE IMPLANT; CHEMISTRY; DISEASE MODEL; LAPAROSCOPY; MATERIALS TESTING; MECHANICAL STRESS; METHODOLOGY; PATHOLOGY; PERITONITIS; SPRAGUE DAWLEY RAT; SURGICAL INFECTION;

ABSORBABLE IMPLANTS; ADHESIONS; ANIMALS; BIOCOMPATIBLE MATERIALS; CARBOXYMETHYLCELLULOSE; CELLULOSE; DISEASE MODELS, ANIMAL; FEMALE; LAPAROSCOPY; MATERIALS TESTING; PERITONITIS; POLYETHYLENE GLYCOLS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; STRESS, MECHANICAL; SURGICAL WOUND INFECTION; SWINE;

EID: 0033624844     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(99)00642-1     Document Type: Article

References (25)

1. Strickler B., Blanco J., Fox H.E. The gynecologic contribution to intestinal obstruction in females. J Am Coll Surg. 178:1994;617-622.
2. Garrett H.E., Mathews J. Reoperative median sternotomy. Ann Thorac Surg. 48:1989;305-307.
3. Stout A.L., Steege J.F., Dodson W.C., Hughes C.L. Relationship of laparoscopic findings to self-report of pelvic pain. Am J Obstet Gynecol. 145:1991;73-79.
4. Howard F.M. The role of laparoscopy in chronic pelvic pain promise and pitfalls . Obstet Gynecol Surv. 48:1993;357-363.
5. DeCherney A.H., Mezer H.C. The nature of post-tubal pelvic adhesions determined by early and late laparoscopy. Fertil Steril. 41:1984;643-646.
6. Trimbos-Kemper T.C.M., Trimbos J.B., van Hall E.V. Adhesion formation after tubal surgery results of the eight-day laparoscopy in 188 patients . Fertil Steril. 43:1985;396-400.
7. Peters A.A., Trimbos-Kemper G.C., Admiraal C., Trimbos J.B., Hermans J. A randomized clinical trial on the benefit of adhesiolysis in patients with intraperitoneal adhesion and chronic pelvic pain. Br J Obstet Gynaecol. 99:1992;59-62.
8. diZerega G.S., Rodgers K.E. The Peritoneum. 1992;Springer, New York.
9. diZerega G.S. Contemporary adhesion prevention. Fertil Steril. 61:1994;219-235.
10. Wiseman D.M. Polymers for the prevention of surgical adhesions. Domb A.J. Polymeric site-specific pharmacotherapy. 1994;370-400 John Wiley and Sons, New York.
11. Amiji MM, Park K. Surface modification of polymeric biomaterials with PEO, a steric repulsion approach. Polymers of Biological and Bioclinical Significance. ACS Symposium Series 540, American Chemical Society, Washington DC, 1994 Ch 11:134-46.
12. Steinleitner A., Lopec G., Suarez M., Lambert H. An evaluation of Flowgel and an intraperitoneal barrier for the prevention of postsurgical adhesion reformation. Fertil Steril. 57:1992;305-308.
13. Okyuyama N., Rodgers K.E., Wang C.Y., Girgis W., Oz M., St. Amand K., et al. Prevention of retrosternal adhesion formation in a rabbit model using bioresorbable films of polyethylene glycol and polylactic acid. J Surg Res. 78:1998;118-122.
14. Elbert D.L., Hubbell J.A. Reduction of fibrous adhesion formation by a copolymer possessing an affinity for anionic surfaces. J Biomed Mater Res. 42:1998;55-65.
15. Cook S.D., Prewett A.B., Dalton J.E., Whitecloud T.S. Reduction in perineural scar formation after laminectomy with polyactive membrane sheets. Spine. 19:1994;1815-1825.
16. Nagelschmidt M., Minor T., Saad S. Polyethylene glycol 4000 attenuates adhesion formation in rats by suppression of peritoneal inflammation and collagen incorporation. Am J Surg. 176:1998;76-80.
17. Rodgers K.E., Girgis W., Campeau J.D., diZerega G.S. Reduction of adhesion formation by intraperitoneal administration of a recombinant hirudin analog. J Invest Surg. 9:1996;388-391.
18. Rodgers K.E., Girgis W., Campeau J.D., diZerega G.S. Reduction of adhesion formation by intraperitoneal administration of anti-inflammatory peptide 2. J Invest Surg. 10:1997;31-36.
19. Rodgers K.E., Girgis W., St Amand K., Campeau J.D., diZerega G.S. Reduction of adhesion formation in rabbits by intraperitoneal administration of lazaroid formulations. Hum Reprod. 13:1998;2443-2451.
20. Rodgers K.E., Klykken P., Jacobs J. Immunotoxicology of medical devices. Fundam Appl Toxicol. 54:1997;371-378.
21. Tsuchida E., Abe K. Interactions between macromolecules in solution and intermacromolecular complexes. Adv Poly Sci. 45:1982;1-125.
22. Chen J.L., Cyr G.N. Compositions producing adhesion through hydration. Manly R.S. Adhesion in biological systems. 10:1970;163-181 Academic Press, New York.
23. Barcellos I.O., Carobrez S.G., Pires A.T.N., Alvarez-Silva M. In vivo and in vitro responses to polyethylene terephthalate-co-diethylene glycol terephthalate) and polyethylene oxide blends. Biomaterials. 19:1998;2075-2082.
24. Desai N.P., Hubbell J.A. Tissue response to intraperitoneal implants of polyethylene oxide modified polyethylene terephthalate. Biomaterials. 13:1992;505-510.
25. Amiji M.M. Permeability and blood compatibility properties of chitosan-poly(ethylene oxide) blend membranes for haemodialysis. Biomaterials. 16:1995;593-599.