Impairment of the Ca2+-permeable AMPA/kainate receptors by lead exposure in organotypic rat hippocampal slice cultures

Pharmacology and Toxicology

Volumn 87, Issue 5, 2000, Pages 204-210

  Sui, Li ^a   Ruan, Di Yun ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; CALCIUM ION; KAINIC ACID RECEPTOR; LEAD; CALCIUM; COBALT; GLUTAMIC ACID; N METHYLASPARTIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN MAPPING; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEAD POISONING; NERVE CELL PLASTICITY; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TISSUE DISTRIBUTION; ANIMAL; DRUG EFFECT; IN VITRO STUDY; METABOLISM; ORGAN CULTURE TECHNIQUE; PERMEABILITY; SUCKLING; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ANIMALIA;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; ANIMALS, NEWBORN; ANIMALS, SUCKLING; BIOLOGICAL TRANSPORT; CALCIUM; COBALT; GLUTAMIC ACID; HIPPOCAMPUS; LEAD; N-METHYLASPARTATE; ORGAN CULTURE TECHNIQUES; PERMEABILITY; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID;

EID: 0033623636     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2000.pto870503.x     Document Type: Article

References (57)

1. Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead
2. The role of divalent cations in the N-methyl-D-Aspartate response of mouse central neurons in culture
3. Ionotropic glutamate receptors: Their possible role in the expression of hippocampal synaptic plasticity
4. The non-NMDA receptors: Types protein structure and molecular biology
5. Longitudinal analyses of prenatal and postnatal lead exposure and early cognitive development
6. Ligand-gated ion channels in the brain: The amino acid receptor superfamily
7. Prediction of neurotoxic potency of hazardous substances with a modular in vitro test battery
8. Lead increases tetrodotoxin-insensitive spontaneous release of glutamate and GABA from hippocampal neurons
9. Induction of primary response genes by excitatory amino acid receptor agonists in primary astroglial cultures
10. Organotypic monolayer cultures of nervous tissue
11. Development of the hippocampus in vitro: Cell types, synapses and receptors
12. Permeation of calcium ions through non-NMDA glutamate channels in retinal bipolar cells
13. ++]i in rat hippocampal pyramidal neurons in vitro
14. 2+-permeable AMPA receptors
15. 2+ permeability of KA-, AMPA-gated glutamate receptor channels depends on subunit composition
16. Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones
17. Development of calcium-permeable appha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining
18. Enhanced LTP in mice deficient in the AMPA receptor GluR2
19. Calcium regulation of the neuronal growth cone
20. Synaptic transmission in the hippocampus: Critical role for glial cells
21. Regulation of dopaminergic activity, but not tyrosine hydroxylase, is diminished after chronic inorganic lead exposure
22. Responses to N-methyl-D-aspartate and kainic acid in cerebellar granule cells of lead-exposed rat pups
23. 2+ influx underlies potent induction of injury
24. NMDA-Receptor activation increases cytoplasmic calcium concentration in cultured spine cord neurones
25. Calcium-permeable AMPA receptors mediate long-term potentiation in interneurons in the amygdala
26. Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons
27. The action of N-methyl-D-aspartic acid on mouse spinal neurones in culture
28. The physiology of excitatory amino acids in the vertebrate central nervous system
29. Regional decreases in alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid ([3H] AMPA) and 6-[3H]-cyano-7-nitroquinoxaline-2,3-dione ([3H] CNQX) binding in response to chronic low-level lead exposure: Reversal versus potentiation by chronic dopamine agonist treatment
30. Physiological and pathological roles of excitatory amino-acids during central nervous system developments
31. The excitatory amino acid receptors: Their classes, pharmacology and distinct properties in the function of the central nervous system
32. ++ influx into striatal neurons by kainic acid
33. Lead-induced blockage of kainate-sensitive receptor channels
34. Selectivity of the Ca binding site in synaptosome Ca channels
35. Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: Morphology and distribution
36. A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties
37. Characterization of two types of calcium channels in mouse neuroblastoma cells
38. Magnesium gates glutamate-activated channels in mouse central neurones
39. 2+ elevation in cultured hippocampal neurones
40. Thin slice CNS explants maintained on collagen-coated culture dishes
41. Early lead exposure and the hippocampus: A review and recent advances
42. Characterization of glutamate sensitive cells in cultures of neonatal rat cerebellum
43. Comparison of kainate receptors on cerebellar granule neurons and glial progenitor cells
44. Agonist-activated cobalt uptake identifies divalent cation-permeable kainate receptors on neurons and glial cells
45. Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity
46. Glutamate receptor phosphorylation and synaptic plasticity
47. Impairment of long-term potentiation and paired-pulse facilitation in rat hippocampal dentate gyrus following developmental lead exposure in vivo
48. In vitro and in vivo pharmacology of trans- and cis-(+)-1-amino-1,3-cyclopentanedicarboxylie acid: Dissociation of metabotropic and ionotropic excitatory amino acid receptor effects
49. Mechanisms of lead neurotoxicity, or looking beyond the lamppost
50. 'Ultrathin' CNS slices enhanced visualization of neuron structure for electrophysiology and imaging
51. A simple method for organotypic cultures of nervous tissue
52. A family of metabotropic glutamate receptors
53. Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/kainate receptors in organotypic hippocampal cultures
54. Excitatory amino acid transmitters
55. Induction of cobalt accumulation by excitatory amino acids within neurons of the hippocampal slice
56. Cellular and connective organization of slice cultures of the rat hippocampus and fascia dentata
57. The effects of chronic lead exposure on long-term depression in area CA1 and dentate gyrus of rat hippocampus in vitro