Slow rise of Ca2+ and slow release of reactive oxygen species are two cross-talked events important in tumour necrosis factor-α-mediated apoptosis

Free Radical Research

Volumn 33, Issue 3, 2000, Pages 295-304

  Ko, S ^a   Kwok, T T ^a   Fung, K P ^a   Choy, Y M ^a   Lee, C Y ^a   Kong, S K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Ca2+; Cross talk; L929 cells; ROS; TNF

Indexed keywords

ARACHIDONIC ACID; CALCIUM; CASPASE; CHELATING AGENT; EGTAZIC ACID; PHOSPHOLIPASE; PROTEINASE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; 1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; AMINE OXIDE; ANTIOXIDANT; DRUG DERIVATIVE; RECOMBINANT PROTEIN; TEMPOL;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CELL KILLING; CELL STRAIN L 929; FLOW CYTOMETRY; MOUSE; NONHUMAN; RESTRICTION FRAGMENT; ANIMAL; CELL LINE; METABOLISM; PHYSIOLOGY; SPIN LABELING;

ANIMALIA;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CALCIUM; CELL LINE; CHELATING AGENTS; CYCLIC N-OXIDES; EGTAZIC ACID; MICE; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SPIN LABELS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033623365     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760000301461     Document Type: Article

References (26)

1. Cell death induction by receptors of the TNF family: Towards a molecular understanding
2. Molecular mechanisms of tumor necrosis factor-induced cytotoxicity. What we do understand and what we do not
3. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
4. Involvement of different transduction pathways in NF-kappa B activation by several inducers
5. Failure to activate cytosolic phospholipase A2 causes TNF resistance in human leukemic cells
6. Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells
7. The intracellular domain of p55 tumor necrosis factor receptor induces apoptosis which requires different caspases in naive and neuronal PC12 cells
8. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
9. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide
10. Apoptosis: Unmasking the executioner
11. Life and death in a medieval atmosphere
12. Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells
13. Ras signaling in tumor necrosis factor-induced apoptosis
14. The role of calcium in apoptosis
15. Calcium-independent pathway of tumor necrosis factor-mediated lysis of target cells
16. Enhancement of tumor necrosis factor cytotoxicity by lithium chloride is associated with increased inositol phosphate accumulation
17. 2+ concentration and DNA fragmentation
18. Redox regulation of programmed cell death in lymphocytes
19. Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
20. Hemolysis of human red blood cells induced by the combination of diethyldithiocarbamate (DDC) and divalent metals: Modulation by anaerobiosis, certain antioxidants and oxidants
21. Improved sensitivity in flow cytometric intracellular ionized calcium measurement using fluo-3/fura red fluorescence ratios
22. 2+ ATPase family of calcium pumps
23. New calcium indicators and buffers with high selectivity against magnesium and protons: Design, synthesis, and properties of prototype structures
24. Slow increase in intranuclear and cytosolic free calcium concentrations in L929 cells is important in tumour necrosis factor-alpha-mediated cell death
25. Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction
26. TNF-alpha activates at least two apoptotic signaling cascades