Brain serotonin2 receptors in major depression: A positron emission tomography study

Archives of General Psychiatry

Volumn 57, Issue 9, 2000, Pages 850-858

  Yatham, Lakshmi N ^a   Liddle, Peter F ^a   Shiah, I Shin ^a,c   Scarrow, Gayle ^a   Lam, Raymond W ^a   Adam, Michael J ^b   Zis, Athanasios P ^a   Ruth, Thomas J ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b TRIUMF   (Canada)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ANTIDEPRESSANT AGENT; BRAIN RECEPTOR; FLUORINE 18; FLUOXETINE; IMIPRAMINE; PAROXETINE; SEROTONIN 2 RECEPTOR; SERTRALINE; SETOPERONE; TRAZODONE; VENLAFAXINE; DIAGNOSTIC AGENT; FLUORINE; PYRIMIDINONE DERIVATIVE; SEROTONIN RECEPTOR;

ADULT; ARTICLE; BRAIN MAPPING; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; FEMALE; HUMAN; MALE; PATHOGENESIS; POSITRON EMISSION TOMOGRAPHY; RECEPTOR BINDING; SEROTONIN BRAIN LEVEL; AGE; BRAIN; CEREBELLUM; CHEMISTRY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; FRONTAL LOBE; METABOLISM; MIDDLE AGED; OCCIPITAL LOBE; PARIETAL LOBE; SCINTISCANNING; SEX DIFFERENCE; STATISTICS; TEMPORAL LOBE;

ADULT; AGE FACTORS; BRAIN; CEREBELLUM; DEPRESSIVE DISORDER; FEMALE; FLUORINE RADIOISOTOPES; FRONTAL LOBE; HUMANS; MALE; MIDDLE AGED; OCCIPITAL LOBE; PARIETAL LOBE; PYRIMIDINONES; RECEPTORS, SEROTONIN; SEX FACTORS; TEMPORAL LOBE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0033623209     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.57.9.850     Document Type: Article

References (64)

1. 2 binding sites in frontal cortex of suicide victims
2. 2 and β-adrenergic receptor binding in the frontal cortices of suicide victims
3. 3H]-LSD) in the blood platelets of depressed patients
4. 2 and β-adrenergic receptor binding sites in the brain of suicide victims
5. Serotonergic mechanisms in brains of suicide victims
6. Autoradiographic analysis of [3H]ketaserin binding in the human brain postmortem: Effect of suicide
7. 5-HT receptor binding in post-mortem brain from patients with affective disorder
8. 5HT2 receptor changes in major depression
9. Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides
10. 2 sites in cortex and amygdala
11. Brain 5HT2 receptor binding sites in depressed suicide victims
12. 2 receptors in suicide victims: Violence of death, depression and effects of antidepressant treatment
13. Serotonin receptors in suicide victims with major depression
14. 2 receptors and suicide
15. 2 receptors in depression
16. 2 receptor imaging in major depression: Focal changes in orbito-insular cortex
17. 18F]-setoperone during depressive illness and antidepressant treatment with clomipramine
18. 18F]setoperone PET imaging study
19. 18F-setoperone studied in humans using positron emission tomography
20. 5-HT(2A) receptors, roles, and regulation
21. Autoradiographic localization of D1 and D2 dopamine receptors in the human brain
22. Fluorine-18-setoperone: A new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo
23. 18F-labeled setoperone
24. A rating scale of depression
25. Simplified purification and synthesis of F-18 setoperone
26. Decrease in brain serotonin 2 receptor binding in patients with major depression following desipramine treatment: A positron emission tomography study with fluorine-18-labeled setoperone
27. An interactive technique for three-dimensional image registration: Validation for PET, SPECT, MRI, and CT brain studies
28. Comparing function (PET) images: The assessment of significant change
29. Statistical parametric maps in functional imaging: A general linear approach
30. Investigation of the dopaminergic system with positron emission tomography: General issues in modelling
31. Characterization and regional distribution of serotonin S2 receptors in human brain
32. Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis
33. 2, F and t fields
34. 18F]setoperone
35. Regional cerebral blood flow in depression measured by positron emission tomography: The relationship with clinical dimensions
36. A review of functional neuroimaging in mood disorders: Positron emission tomography and depression
37. Concerning the distribution of cerebral muscarinic acetylcholine receptors in Alzheimer's disease
38. μ-Opiate receptors measured by positron emission tomography are increased in temporal lobe epilepsy
39. Effects of age on dopamine and serotonin receptors measured by positron emission tomography in the living human brain
40. 2 receptor availability in healthy human subjects
41. 2 receptors in living human brain
42. Serotonin-2 binding sites in human frontal cortex and hippocampus: Selective loss of S-2A sites with age
43. Ligands and tracers for PET studies of the 5-HT system: Current status
44. Long-term antidepressant treatment decreases spiroperidol-labeled serotonin receptor binding
45. 2) receptors labeled with [3H]spiroperidol by chronic treatment with the antidepressant amitriptyline
46. Differential effects of electroconvulsive shock and antidepressant drugs on serotonin-2 receptors in rat brain
47. 2 receptor-mediated head twitch behavior following antidepressant treatment to mice
48. Serotonin receptor sensitivity after acute and chronic treatment with mianserin
49. Effect of chronic antidepressant treatment and subsequent withdrawal on [3H]-5-hydroxytryptamine and [3H]-spiperone binding in rat frontal cortex and serotonin mediated behavior
50. 2-mediated behavior in the rat following noradrenergic or serotonergic denervation
51. 2 receptors in depression
52. Anteroposterior gradients in cerebral glucose use in schizophrenia and affective disorders
53. Cerebral metabolic rates for glucose in mood disorders
54. Glucose utilization in the temporal cortex of affectively ill patients: Positron emission tomography
55. Regional cerebral blood flow abnormalities in depressed patients with cognitive impairment
56. Frontal and parietal metabolic disturbances in unipolar depression
57. Changes in regional cerebral blood flow on recovery from depression
58. Regional cerebral blood flow in mood disorders, III: Treatment and clinical response
59. Effects of electroconvulsive therapy on brain glucose metabolism: A preliminary study
60. Short-term effects of electroconvulsive treatment on the uptake of 99mTc-exametazime into brain in major depression shown with single photon emission tomography