C-kit and gastrointestinal stroma tumors: More than a marker;C-kit et tumeurs <> gastrointestinales: Plus qu'un nouveau marqueur

Annales de Pathologie

Volumn 20, Issue 1, 2000, Pages 91-92

  Scoazec, J Y ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN S 100; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TUMOR MARKER;

CLASSIFICATION; GASTROINTESTINAL TUMOR; HISTOGENESIS; HUMAN; IMMUNOHISTOCHEMISTRY; MOLECULAR BIOLOGY; PHENOTYPE; PROGNOSIS; PROTEIN ANALYSIS; SHORT SURVEY; STROMA; ARTICLE; PATHOLOGY; STROMA CELL;

GASTROINTESTINAL NEOPLASMS; HUMANS; PROTO-ONCOGENE PROTEINS C-KIT; STROMAL CELLS; TUMOR MARKERS, BIOLOGICAL;

EID: 0033621733     PISSN: 02426498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (6)

1. BEDOSSA P. Les tumeurs stromales du tube digestif. Ann Pathol 1997 ; 17 (Suppl.) : 76-8.
2. KINDBLOM LG, REMOTTI HE, ALDENBORG F, MEIS-KINDBLOM JM. Gastrointestinal pacemaker cell tumor (GIPACT) : gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 1998 ; 152 : 1259-69.
3. SARLOMO-RIKALA M, KOVATICH AJ, BARUSEVICIUS A, MIETTINEN M. CD117 : a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol 1998 ; 11 : 728-34
4. HIROTA S, ISOZAKI K, MORIYAMA Y, HASHIMOTO K, NISHIDA T, ISHIGURO S et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998 ; 279 : 577-80.
5. TANIGUCHI M, NISHIDA T, HIROTA S, ISOZAKI K, ITO T, NOMURA T et al. Effet of c-kit mutation on prognosis og gastrointestinal stromal tumors. Cancer Res 1999 ; 59 : 4297-300.
6. LASOTA J, JASINSKI M, SARLOMO-RIKALA M, MIETTINEN M. Mutations in exon 11 of c-kit occur preferentially in malignant versus begnin gastrointestinal stromal tumors and do not occur in leiomyomas or leimyosarcomas. Am J Pathol 1999 ; 154 : 53-60.