Genetic localization of the Ca2+ channel gene CACNG2 near SCA10 on chromosome 22q13

Epilepsia

Volumn 41, Issue 1, 2000, Pages 24-27

  Burgess, Daniel L ^a   Matsuura, Tohru ^a   Ashizawa, Tetsuo ^a   Noebels, Jeffrey L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Ataxia; Calcium channel; Cerebellum; Epilepsy; Stargazer

Indexed keywords

CALCIUM CHANNEL; MICROSATELLITE DNA; PRIMER DNA;

ARTICLE; ATAXIA; CHROMOSOME 22Q; EPILEPSY; GENE LOCATION; GENETIC LINKAGE; HAPLOTYPE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; ALLELE; ANIMAL; CEREBELLAR ATAXIA; CHROMOSOME 22; DNA SEQUENCE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; METHODOLOGY; MOUSE; PEDIGREE; POLYMERASE CHAIN REACTION;

ALLELES; ANIMALS; CALCIUM CHANNELS; CEREBELLAR ATAXIA; CHROMOSOMES, HUMAN, PAIR 22; DNA PRIMERS; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE (GENETICS); LOD SCORE; MICE; MICROSATELLITE REPEATS; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 0033621644     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.2000.tb01500.x     Document Type: Article

References (13)

1. Zu L, Figueroa KP, Grewal R, Pulst SM. Mapping of a new autosomal dominant spinocerebellar ataxia to chromosome 22. Am J Hum Genet 1999;64:594-9.
2. Matsuura T, Achari M, Khajavi M, Bachinski LL, Zoghbi HY, Ashizawa T. Mapping of the gene for a novel spinocerebellar ataxia with pure cerebellar signs and epilepsy. Ann Neurol 1999; 45:407-11.
3. Letts VA, Valenzuela A, Kirley JP, Sweet HO, Davisson MT, Frankel WN. Genetic and physical maps of the stargazer locus on mouse chromosome 15. Genomics 1997;43:62-8.
4. 2+-channel gamma subunit. Nat Genet 1998;19:340-7.
5. Noebels JL, Qiao X, Bronson RT, Spencer C, Davisson MT. Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures. Epilepsy Res 1990;7:129-35.
6. Qiao X, Chen L, Gao H, et al. Cerebellar brain-derived neurotrophic factor-TrkB defect associated with impairment of eyeblink conditioning in Stargazer mutant mice. J Neurosci 1998;18:6990-9.
7. Fletcher CF, Lutz CM, O'Sullivan TN. et al. Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell 1996;87:607-17.
8. Noebels JL, Sidman RL. Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering. Science 1979;204: 1334-6.
9. 1A-voltage-dependent calcium channel. Nat Genet 1997;15:62-9.
10. Gyapay G, Schmitt K, Fizames C, et al. A radiation hybrid map of the human genome. Hum Mol Genet 1996;5:339-46.
11. Stewart EA, McKusick KB, Aggarwal A, et al. An STS-based radiation hybrid map of the human genome. Genome Res 1997;7: 422-33.
12. Dib C, Faure S, Fizames C, et al. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 1996; 380:152-4.
13. Mouse Genome Database (MGD), Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine. World Wide Web (URL: http://www.informatics.jax.org/). February, 1999.