In vitro and in vivo toxicological study of the Pterodon pubescens seed oil

Toxicology Letters

Volumn 108, Issue 1, 1999, Pages 27-35

  Sabino, K C C ^a   Gayer, C R M ^a   Vaz, L C A ^a   Santos, L R L ^a   Felzenszwalb, I ^a   Coelho, M G P ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Acute toxicity; Cytotoxicity; Mutagenicity; Pterodon pubescens

Indexed keywords

PLANT EXTRACT; PTERODON PUBESCENS OIL; UNCLASSIFIED DRUG; VEGETABLE OIL;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CONTROLLED STUDY; CYTOTOXICITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; METABOLIC ACTIVATION; MONONUCLEAR CELL; MOUSE; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PLANT SEED; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM;

ANIMALS; CELL SURVIVAL; CYTOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FABACEAE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, INBRED DBA; MUTAGENICITY TESTS; MUTAGENS; PLANT OILS; PLANTS, MEDICINAL; SEEDS;

ANIMALIA; MAMMALIA; PTERODON PUBESCENS; SALMONELLA;

EID: 0033618440     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00110-1     Document Type: Article

References (29)

1. Ames B.N., McCann J., Yamasaki E. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat. Res. 31:1975;347-364.
2. Ayrton A.D., Neville S., Ioannides C. Cytosolic activation of aminoanthracene: implications in its use as a diagnostic mutagen in the Ames Test. Mutat. Res. 265:1992;1-8.
3. Beekman A.C., Woerdenbag H.J., Kampinga H.H., Konings A.W.T. Cytotoxicity of artemisin, a dimer of dihydroartemisin, artemisitene and eupatoriopicrin as evaluated by the MTT and clonogenic assay. Phytother. Res. 10:1996;140-144.
4. Boyum A. A one-stage procedure for isolation of granulocytes and lymphocytes from human blood. General sedimentation properties of white blood cells in a Ig gravity field. Scand. J. Clin. Lab. Invest. 21:1968;77-89.
5. Braz Filho R., Gottlieb O.R., Viegas Assumpção R.M. A Química de Leguminosas Brasileiras. XXVIII [1] - As isoflavonas de Pterodon pubescens. Ann. Acad. Brasil. Ciênc. 42(Suppl.):1970;111-113.
6. Chan P.K., Hayes A.W. Acute toxicity and eye irritancy. Hayes A.W. Principles and Methods of Toxicology. 3rd edition:1994;579-647 Raven Press, New York.
7. a edição. Edição de Carlos Silva Araújo, S.A., p. 222.
8. Cruz, G.L., 1965. Livro Verde das Plantas Medicinais e Industriais do Brasil, vol. 2. 1st edition. Brazil, pp. 779-780.
9. Dimas K., Demetzos C., Marsellos M., Sotiriadou R., Malamas M., Kokkinopoulos D. Cytotoxic activity of labdane type diterpenes against human leukemic cell lines in vitro. Planta Med. 64:1998;208-211.
10. da Luz Dias F., Takahashi C.S., Sakamoto-Hojo E.T., Vichnewski W., Sarti S.J. Genotoxicity of the natural cercaricides `Sucupira' oil and eremanthine in mammalian cells in vitro and in vivo. Environ. Mol. Mutag. 26:1995;338-344.
11. Fascio M., Mors W.B., Gilbert B., Mahajan I.R., Monteiro M.B., Dos Santos Filho D., Vichnewiski W. Diterpenoid furans from Pterodon species. Phytochemistry. 15:1976;201-203.
12. Fowler B.A., Kleinow K.M., Squibb K.S., Lucier G.W., Hayes W. Organelles as tools in toxicology. Hayes A.W. Principles and Methods of Toxicology. 3rd edition:1994;1201-1230 Raven Press, New York.
13. Gomes E.M., Souto P.R.F., Felzenszwalb I. Skark-cartilage containing preparation protects cells against hydrogen peroxide induced damage and mutagenesis. Mutat. Res. 367:1996;203-208.
14. Gomes-Carneiro M.R., Felzenszwalb I., Paumgartten F.J. Mutagenicity testing (+/-)-camphor, 1,8-cineole, citral, citronellal, (-)-menthol and terpineol with the Salmonella/microsome assay. Mutat. Res. 416:1998;129-136.
15. Hayashi K., Hayashi T., Morita N. Cytotoxic and antitumour activity of scopadulcic acid from Scoparia dulcis L. Phytother. Res. 6:1992;6-9.
16. Kubo I., Chaudhuri S.K., Kubo Y., Sanchez Y., Ogura T., Saito T., Ishikawa H., Haraguchi H. Cytotoxic and antioxidative sesquiterpenoids from Heterotheca inuloides. Planta Med. 62:1996;427-430.
17. Levin D.C., Hollstein M., Christman M.F., Schwiers E.A., Ames B.N. A new Salmonella tester strain (TA102) with A.T base pairs at the site of mutation defects oxidative damage. Proc. Natl. Acad. Sci. USA. 79:1982;7445-7449.
18. Marczilo T., Ioannides C. Bioactivation of 6-aminochrysene by animal and human hepatic preparations: contributions of microsomal and cytosolic enzyme systems. Mutagenesis. 9:1994;233-239.
19. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutat. Res. 113:1983;173-215.
20. Mors W.B., dos Santos Filho M.F., Monteiro H.J., Gilbert B. Chomoprophylactic agent in Schistosomiasis: 14,15-epoxygeranylgeraniol. Science. 157:1967;950-951.
21. Mossman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65:1983;55-63.
22. Novogrodsky A., Rubin A.L., Stenzel K.H. Selective suppression by adherent cells, prostaglandin, and cyclic AMP analogues of blastogenesis induced by different mitogens. J. Immunol. 122:1979;1-7.
23. Nunan E.A., Carvalho M.G., Pilo-Veloso D., Turchetti-Maia R.M.M., Ferreira-Alves D.L. Furane diterpenes with anti- and pro-inflammatory activity. Braz. J. Med. Biol. Res. 15:1982;450.
24. Pio Correa M. Dicionario das plantas úteis do Brasil e das exóticas cultivadas. 1975;129 Instituto Brasileiro de Desenvolvimento Florestal, Rio de Janeiro.
25. Ruschen S., Stellberg W., Warnatz H. Kinetics of cytokine secretion by mononuclear cells of the blood from rheumatoid arthritis patients are different from those of healthy controls. Clin. Exp. Immunol. 89:1992;32-37.
26. Sabino, K.C.C., Castro, F.A. Oliveira, J.C.R. Dalmau, S.R.A., Coelho M.G.P., 1999. Successful therapy of collagen-induced arthritis in mice with a hydroalcoholic extract of seeds of Pterodon pubescens. Phytother. Res. (in press).
27. Torrenegra R., Bauereib P., Achenbach H. Homoormosanine-type alkaloids from Bowdichia virgilioides. Phytochemistry. 28:1989;2219-2221.
28. Venitt, S., Crofton-Sleigh, C., Foster, R., 1984. Bacterial mutation assays using reverse mutation. In: Mutagenicity Testing: A Practical Approach. IRL Press, Washington DC, pp. 45-98.
29. Yahagi T., Degawa M., Seino Y., Matsushima T., Nagao M., Sugimura T., Hashimoto Y. Mutagenicity of carcinogenic azodyes and their derivatives. Cancer Lett. 1:1975;91-96.