Mutagenicity testing of (±)-camphor, 1,8-cineole, citral, citronellal, (-)-menthol and terpineol with the Salmonella/microsome assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 416, Issue 1-2, 1998, Pages 129-136

  Gomes Carneiro, Maria Regina ^a   Felzenszwalb, Israel ^b   Paumgartten, Francisco J R ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Univ de Estado do Rio de Janeiro   (Brazil)

Author keywords

Ames test; Essential oil; Genotoxicity; Monoterpene; Salmonella typhimurium

Indexed keywords

AROCLOR 1254; CAMPHOR; CINEOLE; CITRAL; CITRONELLAL; TERPINEOL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIVER; MALE; METABOLIC ACTIVATION; MUTAGEN TESTING; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SALMONELLA TYPHIMURIUM;

DRYOBALANOPS; SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0031660866     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00077-1     Document Type: Article

References (12)

1. O. Sticher, Plant mono-, di- and sesquiterpenoids with pharmacological or therapeutical activity, in: H. Wagner, P. Wolff (Eds.), New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutic Activity, Springer-Verlag, Berlin, 1977, pp. 137-176.
2. R.E. Erikson, The industrial importance of monoterpenes and essential oils, Lloydia 39 (1976) 8-20.
3. A.Y. Leung, Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics, Wiley, New York, 1980.
4. D.M. Maron, B.N. Ames, Revised methods for Salmonella mutagenicity test, Mutat. Res. 113 (1983) 173-215.
5. D.F.V. Lewis, C. Ionnides, D.V. Parke, COMPACT and molecular structure in toxicity assessment: a prospective evaluation of 30 chemicals currently being tested for carcinogenicity by the NCI/NTP, Environ. Health Perspect. 104 (1996) 1011-1016, Suppl. 5.
6. M. Ishidate, T. Sofuni, K. Yoshikawa, M. Hayashi, T. Nohmi, M. Sawada, A. Matsuoka, Primary mutagenicity screening of food additives currently used in Japan, Food Chem. Toxicol. 22 (1981) 623-636.
7. H.P.S. Zamith, M.N.P. Vidal, G. Speit, F.J.R. Paumgartten, Evaluation of the Genotoxicity of Citral in Mammalian Cells in Vitro, Proceedings of the 22nd Annual Meeting of the European Environmental Mutagen Society, Berlin, Germany, August 31st-September 4th, 1992 (Abstract).
8. A. Kamasaki, H. Takahashi, N. Tsumura, J. Niwa, T. Fujita, S. Urasawa, Genotoxicity of flavoring agents, Mutat. Res. 105 (1982) 387-392.
9. P.H. Andersen, N.J. Jensen, Mutagenic investigation of peppermint oil in the Salmonella/mammalian-microsome test, Mutat. Res. 138 (1984) 17-20.
10. D.E. Levin, M.C. Hollstein, M.F. Christman, E.A. Schwiers, B.N. Ames, A new Salmonella tester strain (TA102) with A-T base pairs at the site of mutation detects oxidative mutagens, Proc. Natl. Acad. Sci. USA 79 (1982) 7445-7449.
11. N. Kanematsu, K.I. Shibata, Investigation of DNA reactivity of endodontic agents by rec-assay, Gifu-Shika-Gakkai-Zasshi 17 (1990) 592-597.
12. H.C. Goel, S. Singh, S.P. Singh, Radiomodifying influence of camphor on sister-chromatid exchange induction in mouse bone marrow, Mutat. Res. 224 (1989) 157-1609.