Cyclic dipeptides. 3.1 Synthesis of methyl (R)-6-[(tert- butoxycarbonyl)amino]-4,5,6,7-tetrahydro-2-methyl-5-oxo-1,4-thiazepine-3- carboxylate and its hexahydro analogues: Elaboration of a novel dual ACE/NEP inhibitor

Journal of Organic Chemistry

Volumn 64, Issue 9, 1999, Pages 3019-3025

  Crescenza, Angela ^a   Botta, Maurizio ^a   Corelli, Federico ^a   Santini, Antonello ^b   Tafi, Andrea ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALLENE DERIVATIVE; CYCLOPEPTIDE; DIPEPTIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; KETONE; MESYLIC ACID DERIVATIVE; PEPTIDE DERIVATIVE; SULFONIC ACID DERIVATIVE; THIAZEPINE DERIVATIVE; THIOL GROUP;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; OXIDATION; PEPTIDE SYNTHESIS; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY;

EID: 0033617331     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo981425v     Document Type: Article

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