Initial characterization of the nascent polypeptide-associated complex in yeast

Yeast

Volumn 15, Issue 5, 1999, Pages 397-407

  Reimann, Barbara ^a   Bradsher, John ^b   Franke, Jacqueline ^a   Hartmann, Enno ^c   Wiedmann, Martin ^b   Prehn, Siegfried ^a   Wiedmann, Brigitte ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

NAC; Nascent polypeptide associated complex; Protein synthesis; Saccharomyces cerevisiae

Indexed keywords

POLYPEPTIDE; PROTEIN SUBUNIT;

ARTICLE; CONTROLLED STUDY; FUNGUS GROWTH; MOLECULAR WEIGHT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RIBOSOME; SACCHAROMYCES CEREVISIAE; TEMPERATURE;

BETA-FRUCTOFURANOSIDASE; BLOTTING, WESTERN; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FUNGAL PROTEINS; GENE DELETION; GLYCOSIDE HYDROLASES; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; PRECIPITIN TESTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBOSOMES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

FUNGI; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0033616846     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0061(19990330)15:5<397::AID-YEA384>3.0.CO;2-U     Document Type: Article

References (30)

1. Carlson, M. and Botstein, D. (1982). Two differentially regulated mRnas with different 5′ends encode secreted and intracellular forms of yeast invertase. Cell 28, 145-154.
2. Deng, J. M. and Behringer, R. R. (1995). An insertional mutation in the BTF3 transcription factor gene leads to an early postimplantation lethality in mice. Transgenic Res. 4, 264-269.
3. Emr, S. D., Vassarotti, A., Garrett, J., Geller, B. I., Takeda, M. and Douglas, M. G. (1986). The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J. Cell Biol. 102, 523-533.
4. Flores, O., Lu, H. and Reinberg, D. (1992). Factors involved in specific transcription by mammalian RNA polymerase II. J. Biol. Chem. 267, 2786-2793.
5. George, R., Beddoe, T., Landl, K. and Lithgow, T. (1998). The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo. Proc. Natl Acad. Sci. USA 95, 2296-2301.
6. Gorlich, D., Kurzchalia, T. V., Wiedmann, M. and Rapoport, T. A. (1991). Probing the molecular environment of translocating polypeptide chains by cross-linking. Meth. Cell Biol. 34, 241-262.
7. Guthrie, C. and Fink, G. R. (Eds) (1991). Meth. Enzymol. Guide Yeast Genet. Mol. Biol. 194, 389-398.
8. Hu, G. Z. and Ronne, H. (1994). Yeast BTF3 protein is encoded by duplicated genes and inhibits the expression of some genes in vivo. Nucleic Acids Res. 22, 2740-2743.
9. Jungnickel, B. and Rapoport, T. A. (1995). A post-targeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell 82, 261-270.
10. Kaiser, C., Michaelis, S. and Mitchell, A. (1994). Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Plainview, New York.
11. Lauring, B., Sakai, H., Kreibich, G. and Wiedmann, M. (1995a). Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum. Proc. Natl Acad. Sci. USA 92, 5411-5415.
12. Lauring, B., Kreibich, G. and Wiedmann, M. (1995b). The intrinsic ability of ribosomes to bind to endoplasmic reticulum membranes is regulated by signal recognition particle and nascent-polypeptide-associated complex. Proc. Natl Acad. Sci. USA 92, 9435-9439.
13. Markesich, D. and Beckingham, K. (1997). 38th Annual Drosophila Research Conference, Program and Abstract, 52.
14. Millman, J. S. and Andrew, D. W. (1997). Switching the model: a concerted mechanism for GTPases in protein targeting. Cell 89, 673-676.
15. Møller, I., Jung, M., Beatrix, B., Levi, R., Kreibich, G., Zimmermann, R., Wiedmann, M. and Lauring, B. (1998). A general mechanism for regulation of access to the translocon: competition for a membrane attachment site on ribosomes. Proc. Natl. Acad. Sci. USA 95, 13425-13430
16. Neuhof, A., Rolls, M. M., Jungnickel, B., Kalies, K.-U. and Rapoport, T. A. (1998). Binding of signal recognition particle gives ribosome/nascent chain complexes a competetive advantage in endoplasmic reticulum membrane interaction. Mol. Biol. Cell 9, 103-115.
17. Neupert, W. and Lill, R. (1994). Cradle at the ribosome. Nature 370, 421-422.
18. Parthun, M. R., Mangus, D. A. and Jaehning, J. A. (1992). The Egd1 product, a yeast homolog of human BTF3, may be involved in GAL4 DNA binding. Mol. Cell. Biol. 12, 5683-5689.
19. Powers, T. and Walter, P. (1996). The nascent polypeptide-associated complex modulates interactions between the signal recognition particle and the ribosome. Current Biology 6, 331-338.
20. Raden, D. and Gilmore, R. (1998). Signal recognition particle-dependent targeting of ribosomes to the rough endoplasmic reticulum in the absence and presence of the nascent polypeptide-associated complex. Mol. Biol. Cell 8, 117-130.
21. Schneider, B. L., Steiner, B., Seufert, W. and Futcher, A. B. (1996). pMPY-ZAP: a reusable polymerase chain reaction-directed gene disruption cassette for Saccharomyces cerevisiae. Yeast 12, 129-134.
22. Shi, X., Parthun, M. R. and Jaehning, J. A. (1995). The yeast EGD2 gene encodes a homologue of the αNAC subunit of the human nascent-polypeptide-associated complex. Gene 165, 199-202.
23. Sikorski, R. S. and Hieter, P. (1989). A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27.
24. Wang, S., Sakai, H. and Wiedmann, M. (1995). NAC covers ribosome-associated nascent chains, thereby forming a protective environment for regions of nascent chains just emerging from the peptidyl transferase center. J. Cell Biol. 130, 519-528.
25. Wiedmann, B., Sakai, H., Davis, T. and Wiedmann, M. (1994). A protein complex required for signal-sequence-specific sorting and translocation. Nature 370, 434-440.
26. Wiedmann, M., Wiedmann, B., Voigt, S., Wachter, E., Müller, H.-G. and Rapoport, T. A. (1988). Post-translational transport of proteins into microsomal membranes of Candida maltosa. EMBO J. 7, 1763-1768.
27. Wickner, W. (1995). The nascent-polypeptide-associated complex: having a 'NAC' for fidelity in translocation. Proc. Natl Acad. Sci. USA 92, 9433-9434.
28. Yotov, W. V. and St.-Arnaud, R. (1996). Differential splicing-in of a proline-rich exon converts αNAC into a muscle-specific transcription factor. Genes Dev. 10, 1763-1772.
29. Zheng, X.-M., Black, D., Chambon, P. and Egly, J.-M. (1990). Sequencing and expression of complementary DNA for the general transcription factor BTF3. Nature 344, 556-559.
30. Zheng, X.-M., Moncollin, V., Egly, J.-M. and Chambon, P. (1987). A general transcription factor forms a stable complex with RNA polymerase B (II). Cell 50, 361-368.