Repeated stress increases catalytic TrkB mRNA in rat hippocampus

Neuroscience Letters

Volumn 267, Issue 2, 1999, Pages 81-84

  Nibuya, Masashi ^a   Takahashi, Michihiro ^a   Russell, David S ^b   Duman, Ronald S ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

Antidepressant; Brain derived neurotrophic factor; Depression; Stress; TrkB; Tyrosine kinase

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; ISOPROTEIN; MESSENGER RNA; PROTEIN TYROSINE KINASE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GRANULE CELL; HIPPOCAMPUS; IMMOBILIZATION STRESS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; RECEPTOR UPREGULATION; RNA ANALYSIS;

ANIMALS; BLOTTING, NORTHERN; CATALYTIC DOMAIN; CORTICOSTERONE; HIPPOCAMPUS; IMMOBILIZATION; IN SITU HYBRIDIZATION; INJECTIONS, SUBCUTANEOUS; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RNA, MESSENGER; SEQUENCE DELETION; STRESS, PSYCHOLOGICAL;

EID: 0033612159     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00335-3     Document Type: Article

References (18)

1. Barbany G., Persson H. Adrenalectomy attenuates kainic acid-elicited increases of messenger RNAs for neurotrophins and their receptors in the rat brain. Neuroscience. 54:(4):1993;909-922.
2. Beck K.D., Lamballe F., Klein R., Barbacid M., Schauwecker P.E., McNeil T.H., Finch C.E., Hefti F., Day J.R. Induction of non-catalytic TrkB neurotrophin receptors during axonal sprouting in the adult hippocampus. J. Neurosci. 13:1993;4001-4014.
3. Bremner J.D., Randall P., Scott T.M., Bronen R.A., Seibyl J.P., Southwick S.M., Delaney R.C., McCarthy G., Charney D.S., Innis R.B. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am. J. Psychiatry. 152:1995;973-981.
4. Duman R.S., Heninger G.R., Nestler E.J. A molecular and cellular theory of depression. Arch. Gen. Psychiatry. 54:1997;597-606.
5. Eide F.F., Vining E.R., Eide B.L., Zang K., Wang X-Y, Reichardt L.F. Naturally occurring truncated trkB receptors have dominant negative inhibitory effects on brain-derived neurotrophic factor signaling. J. Neurosci. 16:1996;3123-3129.
6. Lindsay R.M., Wiegand S.J., Altar C.A., DiStefano P.S. Neurotrophic factors: from molecule to man. Trends Neurosci. 17:1994;182-190.
7. McEwen B.S., Sapolsky R.M. Stress and cognitive function. Curr. Opin. Neurobiol. 5:1990;205-216.
8. Merlio J.P., Ernfors P., Kokaia Z., Middlemas D.S., Bengzon J., Kokaia M., Smith M.L., Siesjo B.K., Hunter T., Lindvall O., Persson H. Increased production of the TrkB protein tyrosine kinase receptor after brain insult. Neuron. 10:1993;151-164.
9. Meyer J.S., Micco D.J., Stephenson B.S., Krey L.D., McEwen B.S. Subcutaneous implantation method for chronic glucocorticoid replacement therapy. Physiol. Behav. 22:1979;687-870.
10. Metsis M., Timmusk T., Arenas E., Persson H. Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation. Proc. Natl. Acad. Sci. USA. 90:1993;8802-8806.
11. Nibuya M., Morinobu S., Duman R.S. Regulation of BDNF and TrkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 15:1995;7539-7547.
12. Ortiz J., Fitzgerald L.W., Lane S., Terwilliger R., Nestler E.J. Biochemical adaptations in the mesolimbic dopamine system in response to repeated stress. Neuropsychopharmacology. 14:1996;443-452.
13. Ortiz J., DeCaprio J.L., Kosten T.A., Nestler E.J. Strain-selective effects of corticosterone on locomotor sensitization to cocaine and on levels of tyrosine hydroxylase and glucocorticoid receptor in the ventral tegmental area. Neuroscience. 67:1995;383-397.
14. Sapolsky R.M. Stress, glucocorticoids, and damage to the nervous system: the current state of confusion. Stress. 1:1996;1-19.
15. Sheline Y.I., Wang P.W., Gado M.H., Csernannsky J.G., Vannier M.W. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. USA. 93:1996;3908-3913.
16. Smith M.A., Makino S., Kvetnansky R., Post R.M. Stress alters the express of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J. Neurosci. 15:1995;1768-1777.
17. Thoenen H. Neurotrophins and neuronal plasticity. Science. 270:1995;593-598.
18. Wilner P. The validity of animal models of depression. Psychopharmacology. 83:1984;1-16.