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Volumn 14, Issue 6, 1996, Pages 443-452

Biochemical adaptations in the mesolimbic dopamine system in response to repeated stress

Author keywords

Cocaine; Cyclic AMP dependent protein kinase; Ethanol; G proteins; Glial fibrillary acidic protein; Morphine; Neurofilaments; Nucleus accumbens; Restraint stress; Tyrosine hydroxylase; Unpredictable stress; Ventral tegmental area

Indexed keywords

ALCOHOL; COCAINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; FLUOXETINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHINE; TYROSINE 3 MONOOXYGENASE;

EID: 0030174291     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0893-133X(95)00152-4     Document Type: Article
Times cited : (150)

References (59)
  • 1
    • 0026047110 scopus 로고
    • Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions
    • Beitner-Johnson D, Nestler EJ (1991): Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions. J. Neurochem 57:344-347
    • (1991) J. Neurochem , vol.57 , pp. 344-347
    • Beitner-Johnson, D.1    Nestler, E.J.2
  • 2
    • 0027375232 scopus 로고
    • Chronic morphine impairs axoplasmic transport in the mesolimbic dopamine system of the rat brain
    • Beitner-Johnson D, Nestler EJ (1993): Chronic morphine impairs axoplasmic transport in the mesolimbic dopamine system of the rat brain. NeuroReport 5:57-60
    • (1993) NeuroReport , vol.5 , pp. 57-60
    • Beitner-Johnson, D.1    Nestler, E.J.2
  • 3
    • 0025942541 scopus 로고
    • Dopaminergic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine-and cocaine-regulated phosphoproteins
    • Beitner-Johnson D, Guitart X, Nestler EJ (1991): Dopaminergic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine-and cocaine-regulated phosphoproteins. Brain Res 561:146-149
    • (1991) Brain Res , vol.561 , pp. 146-149
    • Beitner-Johnson, D.1    Guitart, X.2    Nestler, E.J.3
  • 4
    • 0026695214 scopus 로고
    • Neuofilaments and the mesolimbic dopamine system: Common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area
    • Beitner-Johnson D, Guitart X, Nestler EJ (1992): Neuofilaments and the mesolimbic dopamine system: Common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area. J Neurosci 12:2165-2176
    • (1992) J Neurosci , vol.12 , pp. 2165-2176
    • Beitner-Johnson, D.1    Guitart, X.2    Nestler, E.J.3
  • 5
    • 0027381134 scopus 로고
    • Glial fibrillary acidic protein and the mesolimbic dopamine system: Regulation by chronic morphine and Lewis-Fischer strain differences in the rat ventral tegmental area
    • Beitner-Johnson D, Guitart X, Nestler EJ (1993): Glial fibrillary acidic protein and the mesolimbic dopamine system: Regulation by chronic morphine and Lewis-Fischer strain differences in the rat ventral tegmental area. J Neurochem 61:1766-1773
    • (1993) J Neurochem , vol.61 , pp. 1766-1773
    • Beitner-Johnson, D.1    Guitart, X.2    Nestler, E.J.3
  • 7
    • 0026088339 scopus 로고
    • Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear
    • Campeau S, Hayward MD, Hope BT, Rosen JB, Nestler EJ, Davis M (1991): Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear. Brain Res 565:349-352
    • (1991) Brain Res , vol.565 , pp. 349-352
    • Campeau, S.1    Hayward, M.D.2    Hope, B.T.3    Rosen, J.B.4    Nestler, E.J.5    Davis, M.6
  • 8
    • 0025130599 scopus 로고
    • Critical role of the hypothalamic pituitary adrenal axis in amphetamine-induced sensitization of behavior
    • Cole BJ, Cador M, Stinus L, Rivier C, Rivier J, Vale W, Le Moal M, Koob GF (1990): Critical role of the hypothalamic pituitary adrenal axis in amphetamine-induced sensitization of behavior. Life Sci 47:1715-1720
    • (1990) Life Sci , vol.47 , pp. 1715-1720
    • Cole, B.J.1    Cador, M.2    Stinus, L.3    Rivier, C.4    Rivier, J.5    Vale, W.6    Le Moal, M.7    Koob, G.F.8
  • 9
    • 0026468179 scopus 로고
    • Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: Studies of conditioned reward
    • Cunningham ST, Kelley AE (1992): Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: Studies of conditioned reward. Brain Res Bull, 29:675-680
    • (1992) Brain Res Bull , vol.29 , pp. 675-680
    • Cunningham, S.T.1    Kelley, A.E.2
  • 10
    • 0027160218 scopus 로고
    • Hyperactivity and sensitization to psychostimulants following cholera toxin infusion into the nucleus accumbens
    • Cunningham ST, Kelley AE (1993): Hyperactivity and sensitization to psychostimulants following cholera toxin infusion into the nucleus accumbens. J Neurosci 13: 2342-2350
    • (1993) J Neurosci , vol.13 , pp. 2342-2350
    • Cunningham, S.T.1    Kelley, A.E.2
  • 11
    • 0027232723 scopus 로고
    • Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels - A comparison between Sprague-Dawley, Fischer 344 and Lewis rats
    • Dhabbar FS, McEwen BS, Spencer RL (1993): Stress response, adrenal steroid receptor levels and corticosteroid-binding globulin levels - a comparison between Sprague-Dawley, Fischer 344 and Lewis rats. Brain Res 616:89-98
    • (1993) Brain Res , vol.616 , pp. 89-98
    • Dhabbar, F.S.1    McEwen, B.S.2    Spencer, R.L.3
  • 12
    • 0025672802 scopus 로고
    • The determinants of stress-induced activation of the prefrontal cortical dopamine system
    • Deutch AY, Roth RH (1990): The determinants of stress-induced activation of the prefrontal cortical dopamine system. Prog Brain Res 85:357-393
    • (1990) Prog Brain Res , vol.85 , pp. 357-393
    • Deutch, A.Y.1    Roth, R.H.2
  • 13
    • 0002988844 scopus 로고
    • Opiates/opioids and reinforcement
    • Korenman SG and Barchas JD (eds), New York, Oxford University Press
    • Dworkin SI, Smith JE (1993): Opiates/opioids and reinforcement. In Korenman SG and Barchas JD (eds), Biological Basis of Substance Abuse, New York, Oxford University Press, pp 327-338
    • (1993) Biological Basis of Substance Abuse , pp. 327-338
    • Dworkin, S.I.1    Smith, J.E.2
  • 14
    • 0028084958 scopus 로고
    • Effects of ventral striatal 6-OHDA lesions or amphetamine sensitization on ethanol consumption in the rat
    • Fahlke C, Hansen S, Engel JA, Hard E (1994): Effects of ventral striatal 6-OHDA lesions or amphetamine sensitization on ethanol consumption in the rat. Pharmacol Biochem Behav 47:345-349
    • (1994) Pharmacol Biochem Behav , vol.47 , pp. 345-349
    • Fahlke, C.1    Hansen, S.2    Engel, J.A.3    Hard, E.4
  • 17
    • 0026042342 scopus 로고
    • Sex and strain differences in circadian rhythm fluctuation of endocrine and immune function in the rat: Implications for rodent models of autoimmune disease
    • Griffin AC, Whitacre CC (1991): Sex and strain differences in circadian rhythm fluctuation of endocrine and immune function in the rat: Implications for rodent models of autoimmune disease. J Neuroimmunol 35:53-64
    • (1991) J Neuroimmunol , vol.35 , pp. 53-64
    • Griffin, A.C.1    Whitacre, C.C.2
  • 18
    • 0026759011 scopus 로고
    • Potential involvement of anxiety in the neurobiology of cocaine
    • Goeders NE (1992): Potential involvement of anxiety in the neurobiology of cocaine. Ann N Y Acad Sci 654:357-367
    • (1992) Ann N Y Acad Sci , vol.654 , pp. 357-367
    • Goeders, N.E.1
  • 19
    • 0028230975 scopus 로고
    • Non-contingent electric foot-shock facilitates the acquisition of intravenous cocaine self-administration in rats
    • Goeders NE, Guerin GF (1994): Non-contingent electric foot-shock facilitates the acquisition of intravenous cocaine self-administration in rats. Psychopharmacology 114:63-70
    • (1994) Psychopharmacology , vol.114 , pp. 63-70
    • Goeders, N.E.1    Guerin, G.F.2
  • 20
    • 0026472075 scopus 로고
    • Fischer and Lewis rats strains differ in basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system
    • Guitart X, Beitner-Johnson DB, Marby D, Kosten TA, Nestler EJ (1992): Fischer and Lewis rats strains differ in basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system. Synapse 12:242-253
    • (1992) Synapse , vol.12 , pp. 242-253
    • Guitart, X.1    Beitner-Johnson, D.B.2    Marby, D.3    Kosten, T.A.4    Nestler, E.J.5
  • 21
    • 0027266774 scopus 로고
    • Lewis and Fischer rat strains display differences in biochemical, electrophysiological, and behavioral parameters: Studies in the nucleus accumbens and locus coeruleus of drug-naive and morphine-treated animals
    • Guitart X, Kogan JH, Berhow MT, Terwilliger RZ, Aghajanian GK, Nestler EJ (1993): Lewis and Fischer rat strains display differences in biochemical, electrophysiological, and behavioral parameters: Studies in the nucleus accumbens and locus coeruleus of drug-naive and morphine-treated animals. Brain Res 611:7-17
    • (1993) Brain Res , vol.611 , pp. 7-17
    • Guitart, X.1    Kogan, J.H.2    Berhow, M.T.3    Terwilliger, R.Z.4    Aghajanian, G.K.5    Nestler, E.J.6
  • 22
    • 0027281102 scopus 로고
    • Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats
    • Hamamura T, Fibiger HC (1993) Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats. Eur J Pharmacol 237:65-71
    • (1993) Eur J Pharmacol , vol.237 , pp. 65-71
    • Hamamura, T.1    Fibiger, H.C.2
  • 23
    • 0025989299 scopus 로고
    • 1 dopamine receptor sensitivity within the rat nucleus accumbens
    • 1 dopamine receptor sensitivity within the rat nucleus accumbens. J Pharmacol Exp Ther 258:882-890
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 882-890
    • Henry, D.J.1    White, F.J.2
  • 24
    • 0026598438 scopus 로고
    • Repeated stressful experiences differently affect limbic dopamine release during and following stress
    • Imperato A, Angelucci L, Casolini P, Zocchi A, Puglisi-Allegra S (1992): Repeated stressful experiences differently affect limbic dopamine release during and following stress. Brain Res 577:194-199
    • (1992) Brain Res , vol.577 , pp. 194-199
    • Imperato, A.1    Angelucci, L.2    Casolini, P.3    Zocchi, A.4    Puglisi-Allegra, S.5
  • 25
    • 0026742907 scopus 로고
    • The neurobiology of drug and alcohol addiction
    • Kalivas PW, Samson HH (eds) (1992): The neurobiology of drug and alcohol addiction. Ann N Y Acad Sci Volume 654
    • (1992) Ann N Y Acad Sci , vol.654
    • Kalivas, P.W.1    Samson, H.H.2
  • 26
    • 0025751604 scopus 로고
    • Dopamine transmission in the initiation and expression of drug-and stress-induced sensitization of motor activity
    • Kalivas PW, Stewart J (1991): Dopamine transmission in the initiation and expression of drug-and stress-induced sensitization of motor activity. Brain Research Rev 16:223-244
    • (1991) Brain Research Rev , vol.16 , pp. 223-244
    • Kalivas, P.W.1    Stewart, J.2
  • 27
    • 0026507628 scopus 로고
    • Drugs of abuse: Anatomy, pharmacology, and function of reward pathways
    • Koob (1992) Drugs of abuse: Anatomy, pharmacology, and function of reward pathways. Trends Pharmacol Sci 13:177-184
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 177-184
  • 28
    • 0025855256 scopus 로고
    • The dopamine hypothesis of the reinforcing properties of cocaine
    • Kuhar MJ, Ritz MC, Boja JW (1991): The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14:299-302
    • (1991) Trends Neurosci , vol.14 , pp. 299-302
    • Kuhar, M.J.1    Ritz, M.C.2    Boja, J.W.3
  • 29
    • 0028204876 scopus 로고
    • Corticosterone circadian secretion differentially facilitates dopamine-mediated psychomotor effect of cocaine and morphine
    • Marinelli M, Piazza PV, Deroche V, Maccari S, Le Moal M, Simon H (1994): Corticosterone circadian secretion differentially facilitates dopamine-mediated psychomotor effect of cocaine and morphine. J Neurosci 14:2724-2731
    • (1994) J Neurosci , vol.14 , pp. 2724-2731
    • Marinelli, M.1    Piazza, P.V.2    Deroche, V.3    Maccari, S.4    Le Moal, M.5    Simon, H.6
  • 30
    • 0028067088 scopus 로고
    • Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress
    • Melia KR, Ryabinin AE, Schroeder R, Bloom FE, Wilson MC (1994): Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress. J Neurosci 14:5929-5938
    • (1994) J Neurosci , vol.14 , pp. 5929-5938
    • Melia, K.R.1    Ryabinin, A.E.2    Schroeder, R.3    Bloom, F.E.4    Wilson, M.C.5
  • 31
    • 0028945718 scopus 로고
    • Behavioral sensitization to cocaine: Modulation by the cyclic AMP system in the nucleus accumbens
    • Miserendino MJD, Nestler EJ (1995): Behavioral sensitization to cocaine: Modulation by the cyclic AMP system in the nucleus accumbens. Brain Res 674:299-306
    • (1995) Brain Res , vol.674 , pp. 299-306
    • Miserendino, M.J.D.1    Nestler, E.J.2
  • 32
    • 0025959674 scopus 로고
    • Stimulus-transcription coupling in the nervous system
    • Morgan JI, Curran T (1991): Stimulus-transcription coupling in the nervous system. Annu Rev Neurosci 14:421-452
    • (1991) Annu Rev Neurosci , vol.14 , pp. 421-452
    • Morgan, J.I.1    Curran, T.2
  • 33
    • 0029045938 scopus 로고
    • Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat cortex
    • Morinobu S, Nibuya M, Duman RS (1995): Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat cortex. Neuropsychopharmacology 12:221-228
    • (1995) Neuropsychopharmacology , vol.12 , pp. 221-228
    • Morinobu, S.1    Nibuya, M.2    Duman, R.S.3
  • 34
    • 0026645205 scopus 로고
    • Molecular mechanisms of drug addiction
    • Nestler EJ (1992): Molecular mechanisms of drug addiction. J Neurosci 12:2439-2450
    • (1992) J Neurosci , vol.12 , pp. 2439-2450
    • Nestler, E.J.1
  • 35
    • 0027761786 scopus 로고
    • Drug addiction: A model for the molecular basis of neural plasticity
    • Nestler EJ, Hope BT, Widnell KL (1993): Drug addiction: A model for the molecular basis of neural plasticity. Neuron 11:995-1006
    • (1993) Neuron , vol.11 , pp. 995-1006
    • Nestler, E.J.1    Hope, B.T.2    Widnell, K.L.3
  • 36
    • 0028999210 scopus 로고
    • Strain-selective effects of corticosterone on locomotor sensitization to cocaine and on levels of tyrosine hydroxylase and glucocorticoid receptor in the ventral tegmental area
    • Ortiz J, DeCaprio JL, Kosten TA, Nestler EJ (1995a): Strain-selective effects of corticosterone on locomotor sensitization to cocaine and on levels of tyrosine hydroxylase and glucocorticoid receptor in the ventral tegmental area. Neuroscience 67:383-397
    • (1995) Neuroscience , vol.67 , pp. 383-397
    • Ortiz, J.1    DeCaprio, J.L.2    Kosten, T.A.3    Nestler, E.J.4
  • 39
    • 0027536676 scopus 로고
    • Emotional but not physical stress enhances intravenous cocaine self-administration in drug-naive rats
    • Ramsey NF, Van Ree JM (1993): Emotional but not physical stress enhances intravenous cocaine self-administration in drug-naive rats. Brain Res 608:216-222
    • (1993) Brain Res , vol.608 , pp. 216-222
    • Ramsey, N.F.1    Van Ree, J.M.2
  • 40
    • 0027305458 scopus 로고
    • The neural basis of drug craving: An incentive-sensitization theory of addiction
    • Robinson TE, Berridge KC (1993): The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Res Rev 18:247-291
    • (1993) Brain Res Rev , vol.18 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 41
    • 0022552189 scopus 로고
    • Neuroendocrine, biogenic amine and behavioral responsiveness to a repeated foot-shock-induced analgesia (FSIA) Stressor in Sprague-Dawley (CD) and Fischer-344 (CDF) rats
    • Rosecrans JA, Robinson SE, Johnson JH, Mokler DJ, Hong JS (1986): Neuroendocrine, biogenic amine and behavioral responsiveness to a repeated foot-shock-induced analgesia (FSIA) Stressor in Sprague-Dawley (CD) and Fischer-344 (CDF) rats. Brain Res 382:71-80
    • (1986) Brain Res , vol.382 , pp. 71-80
    • Rosecrans, J.A.1    Robinson, S.E.2    Johnson, J.H.3    Mokler, D.J.4    Hong, J.S.5
  • 42
    • 0021365828 scopus 로고
    • Stress down-regulates corticosterone receptors in a site-specific manner in the brain
    • Sapolsky RM, Krey LC, McEwen BS (1984): Stress down-regulates corticosterone receptors in a site-specific manner in the brain. Endocrinology 114:287-292
    • (1984) Endocrinology , vol.114 , pp. 287-292
    • Sapolsky, R.M.1    Krey, L.C.2    McEwen, B.S.3
  • 43
    • 0028914467 scopus 로고
    • Molecular mechanisms of drug reinforcement and addiction
    • Self DW, Nestler EJ (1995): Molecular mechanisms of drug reinforcement and addiction. Annu Rev Neurosci 18:463-495
    • (1995) Annu Rev Neurosci , vol.18 , pp. 463-495
    • Self, D.W.1    Nestler, E.J.2
  • 44
    • 0028169618 scopus 로고
    • Inactivation of Gi and Go proteins in nucleus accumbens reduces both cocaine and heroin reinforcement
    • Self DW, Terwilliger RZ, Nestler EJ, Stein L (1994): Inactivation of Gi and Go proteins in nucleus accumbens reduces both cocaine and heroin reinforcement. J Neurosci 14:6239-6247
    • (1994) J Neurosci , vol.14 , pp. 6239-6247
    • Self, D.W.1    Terwilliger, R.Z.2    Nestler, E.J.3    Stein, L.4
  • 45
    • 0029620705 scopus 로고
    • Biochemical adaptations in the rat mesolimbic dopamine system in response to heroin self-administration
    • Self DW, McClenahan A, Terwilliger RZ, Nestler EJ (1995): Biochemical adaptations in the rat mesolimbic dopamine system in response to heroin self-administration. Synapse 21:312-318
    • (1995) Synapse , vol.21 , pp. 312-318
    • Self, D.W.1    McClenahan, A.2    Terwilliger, R.Z.3    Nestler, E.J.4
  • 46
    • 0028298860 scopus 로고
    • Exposure to mild stress enhances the reinforcing efficacy of intravenous heroin self-administration
    • Shaham Y, Stewart J (1994): Exposure to mild stress enhances the reinforcing efficacy of intravenous heroin self-administration. Psychopharmacology 114:523-527
    • (1994) Psychopharmacology , vol.114 , pp. 523-527
    • Shaham, Y.1    Stewart, J.2
  • 47
  • 48
    • 0028921364 scopus 로고
    • Involvement of interleukin-1 in immobilization stress-induced increase in plasma adrenocorticotropic hormone and in release of hypothalamic monoamines in the rat
    • Shintani F, Nakaki T, Kanba S, Sato K, Yagi G, Shiozawa M, Aiso S, Kato R, Asai M (1995): Involvement of interleukin-1 in immobilization stress-induced increase in plasma adrenocorticotropic hormone and in release of hypothalamic monoamines in the rat. J Neurosci 15:1961-1970
    • (1995) J Neurosci , vol.15 , pp. 1961-1970
    • Shintani, F.1    Nakaki, T.2    Kanba, S.3    Sato, K.4    Yagi, G.5    Shiozawa, M.6    Aiso, S.7    Kato, R.8    Asai, M.9
  • 49
    • 0027380778 scopus 로고
    • Behavioral sensitization to stress and psychostimulants: Role of dopamine and excitatory amino acids in the mesocorticolimbic system
    • Sorg BA, Kalivas PW (1993): Behavioral sensitization to stress and psychostimulants: Role of dopamine and excitatory amino acids in the mesocorticolimbic system. Sem Neurosci 5:343-350
    • (1993) Sem Neurosci , vol.5 , pp. 343-350
    • Sorg, B.A.1    Kalivas, P.W.2
  • 50
    • 0027420864 scopus 로고
    • Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine
    • Sorg BA, Chen SY, Kalivas PW (1993): Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine. J Pharmacol Exp Ther 266:424-430
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 424-430
    • Sorg, B.A.1    Chen, S.Y.2    Kalivas, P.W.3
  • 51
    • 0024399181 scopus 로고
    • A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats
    • Sternberg EM, Young SW, Bernardini R, Calogero AE, Ghrousos GP, Gold PW, Wilder RL (1989): A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats. Proc Natl Acad Sci USA 86:4771-4775
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4771-4775
    • Sternberg, E.M.1    Young, S.W.2    Bernardini, R.3    Calogero, A.E.4    Ghrousos, G.P.5    Gold, P.W.6    Wilder, R.L.7
  • 52
    • 0027298681 scopus 로고
    • Robustness of G protein changes in cocaine sensitization shown with immunoblotting
    • Striplin CD, Kalivas PW (1993): Robustness of G protein changes in cocaine sensitization shown with immunoblotting. Synapse 14:10-15
    • (1993) Synapse , vol.14 , pp. 10-15
    • Striplin, C.D.1    Kalivas, P.W.2
  • 53
    • 0025760593 scopus 로고
    • A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function
    • Terwilliger RZ, Beitner-Johnson D, Sevarino KA, Grain SM, Nestler EJ (1991): A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function. Brain Res 548:100-110
    • (1991) Brain Res , vol.548 , pp. 100-110
    • Terwilliger, R.Z.1    Beitner-Johnson, D.2    Sevarino, K.A.3    Grain, S.M.4    Nestler, E.J.5
  • 54
    • 0025370554 scopus 로고
    • Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: Lack of conditioned effects
    • Vezina P, Stewart J (1990): Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: Lack of conditioned effects. Brain Res 516:99-106
    • (1990) Brain Res , vol.516 , pp. 99-106
    • Vezina, P.1    Stewart, J.2
  • 55
    • 0027489712 scopus 로고
    • Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels
    • Vrana SL, Vrana KE, Koves TR, Smith JE, Dworkin SI (1993): Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels. J Neurochem 61:2262-2268
    • (1993) J Neurochem , vol.61 , pp. 2262-2268
    • Vrana, S.L.1    Vrana, K.E.2    Koves, T.R.3    Smith, J.E.4    Dworkin, S.I.5
  • 56
    • 0021348560 scopus 로고
    • The validity of animal models of depression
    • Willner P (1984): The validity of animal models of depression. Psychopharmacology 83:1-16
    • (1984) Psychopharmacology , vol.83 , pp. 1-16
    • Willner, P.1
  • 57
    • 0026020342 scopus 로고
    • Animal models as simulations of depression
    • Willner P (1991): Animal models as simulations of depression. Trends Pharmacol Sci 12:131-136
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 131-136
    • Willner, P.1
  • 58
    • 0002494597 scopus 로고
    • The role of reward pathways in the development of drug dependence
    • Balfour DJK (ed), Oxford, Pergamon, Press
    • Wise RA (1990): The role of reward pathways in the development of drug dependence. In Balfour DJK (ed), Psychotropic Drugs of Abuse. Oxford, Pergamon, Press pp 23-57
    • (1990) Psychotropic Drugs of Abuse , pp. 23-57
    • Wise, R.A.1
  • 59
    • 0028144079 scopus 로고
    • Effects of restraint stress on components of adenylyl cyclase signal transduction in the rat hippocampus
    • Wolfgang D, Chen I, Wand GS (1994): Effects of restraint stress on components of adenylyl cyclase signal transduction in the rat hippocampus. Neuropsychopharmacology 11:187-193
    • (1994) Neuropsychopharmacology , vol.11 , pp. 187-193
    • Wolfgang, D.1    Chen, I.2    Wand, G.S.3


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