Computerized histomorphometric assessment of protocol renal transplant biopsy specimens for surrogate markers of chronic rejection

Transplantation

Volumn 68, Issue 2, 1999, Pages 236-241

  Nicholson, Michael L ^a   Bailey, Elaine ^a   Williams, Simon ^a   Harris, Kevin P G ^a   Furness, Peter N ^a  

^a LEICESTER GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AZATHIOPRINE; COLLAGEN TYPE 3; CYCLOSPORIN; OKT 3; PEROXIDASE; PREDNISOLONE; TENASCIN; THYMOCYTE ANTIBODY;

ALLOGRAFT; ARTICLE; DISEASE MARKER; EARLY DIAGNOSIS; GLOMERULUS FILTRATION RATE; GRAFT FAILURE; GRAFT SURVIVAL; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY GRAFT; KIDNEY GRAFT REJECTION; LEUKOCYTE; MAJOR CLINICAL STUDY; MORPHOMETRICS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; BIOPSY; CHILD; CHRONIC DISEASE; COLLAGEN; COLORING AGENTS; GRAFT REJECTION; HUMANS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TRANSPLANTATION; MIDDLE AGED; PROGNOSIS; REPRODUCIBILITY OF RESULTS;

EID: 0033609461     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199907270-00013     Document Type: Article

References (27)

1. Thorogood J, Van Houwelingen HC, Van Rood JJ, Zantvoort FA, Schreuder GMTh, Persijn GG. Long term results of kidney transplantation in Eurotransplant. In: Paul LC, Solez K, eds. Organ transplantation: long term results. New York: Dekker, 1992: 33.
2. Opelz G, Mickey MR, Terasaki PI. Calculations of long term graft and patient survival in human kidney transplantation. Transplant Proc 1997; 9: 27.
3. Paul LC, et al. Diagnostic criteria for chronic rejection/accelerated graft atherosclerosis in heart and kidney transplants: proposals from the fourth Alexis Carrel Conference on Chronic Rejection and Accelerated Arteriosclerosis in Transplanted Organs. Transplant Proc 1993; 25: 2020.
4. Kasiske BL, Kalil RSN, Lee HS, Rao KV. Histopathological findings associated with chronic, progressive decline in renal allograft function. Kidney Int 1991; 80: 514.
5. Furness PN. Extracellular matrix and the kidney. J Clin Pathol 1996; 49: 355.
6. El Nahas AM. Pathways to renal fibrosis. Exp Nephrol 1995; 3: 71.
7. Paul LC. Chronic renal transplant loss. Kidney Int 1995; 47: 1491.
8. Lemstrom K, Koskinen P, Hayry P. Molecular mechanisms of chronic renal allograft rejection. Kidney Int 1995; 48: 2.
9. Hayry P, Yilmaz S. Chronic allograft rejection: an update. Transplant Proc 1994; 26: 3159.
10. Hunsicker LG, Bennett LE. Design of trials of methods to reduce late allograft loss: the price of success. Kidney Int 1995; 48 (suppl 52): S120.
11. Dimeny E, Wahlberg J, Larsson E, Fellstrom B. Can histopathological findings in early renal allograft biopsies identify patients at risk for chronic vascular rejection? Clin Transplant 1995; 9: 79.
12. Nicholson ML, Attard AR, Bell A, Donnelly PK, Veitch PS, Bell PRF. Renal transplant biopsy using real time ultrasound guidance. Br J Urol 1990; 65: 564.
13. Furness PN. The use of digital images in pathology. J Pathol 1997; 183: 252.
14. Isoniemi H, Taskinen E, Hayry P. Histological chronic allograft damage index accurately predicts chronic renal allograft rejection. Transplantation 1994; 58: 1195.
15. Nickerson P, Jeffrey J, McKenna R, Gough J, Rush D. Do renal allograft function and histology at 6 months post-transplant predict graft function at 2 years? Transplant Proc 1997; 29: 2589.
16. Rush DN, Jeffrey JR, Gough J. Sequential protocol biopsies in renal transplant patients: clinicopathological correlates using the Banff schema. Transplantation 1995; 59: 511.
17. Goumenos DS, Brown CB, Shortland J, el Nahas AM. Myofibroblasts, predictors of progression of mesangial IgA nephropathy? Nephrol Dial Transplant 1994; 9: 1418.
18. Pedagogos E, Hewitson T, Fraser I, Nicholls K, Becker G. Myofibroblasts and arteriolar sclerosis in human diabetic nephropathy. Am J Kidney Dis 1997; 29: 912.
19. Roberts I, Burrows C, Shanks J, Venning M, McWilliam L. Interstitial myofibroblasts: predictors of progression in membranous nephropathy. J Clin Pathol 1997; 50: 123.
20. Gjertson DW, Cecka MJ, Terasaki PI. The relative effects of FK506 and cyclosporine on short and long term kidney graft survival. Transplantation 1995; 60: 1384.
21. Gregory CR, Huang X, Pratt RE, et al. Treatment with rapamycin and mycophenolic acid reduces arterial intimai thickening produced by mechanical injury and allows endothelial replacement. Transplantation 1995; 59: 655.
22. Azuma H, Binder J, Heemann U, Schmid C, Tullius SG, Tilney NL. Effects of RS61443 on functional and morphological changes in chronically rejecting rat kidney allografts. Transplantation 1995; 59: 460.
23. Basadonna GP, Matas AJ, Gillingham KJ, et al. Early versus late acute renal allograft rejection: impact on chronic rejection. Transplantation 1993; 55: 993.
24. Eddy AA. Interstitial macrophages as mediators of renal fibrosis. Exp Nephrol 1995; 3: 76.
25. Furness PN, Rogers-Wheatley L, Harris KPG. Semiautomatic quantitation of macrophages in human renal biopsy specimens in proteinuric states. J Clin Pathol 1997; 50: 118.
26. Wallace WA, Howie SE, Lamb D, Salter DM. Tenascin immuno-reactivity in cryptogenic fibrosing alveolitis. J Pathol 1995; 175: 415.
27. Nicholson ML, McCulloch TA, Harper S, et al. Early measurement of interstitial fibrosis predicts long-term renal function and graft survival in renal transplantation. Br J Surg 1996; 83: 1082.