Caudal is the Hox gene that specifies the most posterior Drosophile segment

Nature

Volumn 400, Issue 6747, 1999, Pages 873-877

  Moreno, Eduardo ^a   Morata, Ginés ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BODY GROWTH; DEVELOPMENT; DROSOPHILA; FLY; FORELIMB; GENE ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; HEAD; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BODY PATTERNING; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENES, HOMEOBOX; GENES, INSECT; HOMEODOMAIN PROTEINS; MALE; TRANSCRIPTION FACTORS;

ARACHNIDA; BRACHYENTERON; ERINACEIDAE; HEXAPODA;

EID: 0033607025     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/23709     Document Type: Article

References (28)

1. Macdonald, P. & Struhl, B. A molecular gradient in early Drosophila embryos and its role in specifying the body pattern. Nature 324, 537-545 (1986).
2. Mlodzik, M., Fjose, A. & Gehring, W. J. Isolation of caudal, a Drosophila homeobox-containing gene with maternal expression, whose transcription forms a concentration gradient at the pre-blastoderm stage. EMBO J. 4, 2961-2969 (1985).
3. Hunter, C. P. & Kenyon, C. Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos. Cell 87, 217-226 (1997).
4. Brooke, N. M., Garcia-Fernandez, J. & Holland, P. W. The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster. Nature 392, 920-922 (1998).
5. McGinnis, W. & Krumlauf, R. Homeobox genes and axial patterning. Cell 68, 283-302 (1992).
6. Basler, K. & Struhl, G. Compartment boundaries and the control of Drosophila limb pattern by Hedgehog protein. Nature 368, 208-214 (1994).
7. Wu, L. H. & Lengyel, J. A. Role of caudal in the hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore. Development 125, 2433-2442 (1996).
8. Calleja, M., Moreno, E., Pelaz, S. & Morata, G. Visualization of gene expression in living adult Drosophila. Science 274, 252-255 (1996).
9. Casares, F., Sanchez, L., Guerrero, I. & Sanchez-Herrero, E. The genital disc of Drosophila melanogaster. I. Segmental and compartmental organization. Dev. Genes Evol. 207, 216-228 (1997).
10. Nöthiger, R., Dübendorfez, A. & Epper, F. Gynandromorphs reveal two separate primordia for male and female genitalia in Drosophila melanogaster. Wilhelm Roux Arch. Dev. Biol. 181, 367-373 (1997).
11. Epper, F. Three-dimensional fate map of the female genital disc of Drosophila melanogaster. Wilhelm Roux Arch. Dev. Biol. 192, 270-274 (1983).
12. Cohen, S. M., Broner, G., Kuntter, F., Jurgens, G. & Jackie, H. Distal-less encodes a homeodomain protein required for limb development in Drosophila. Nature 338, 432-434 (1989).
13. Frasch, M., Hoey, T., Bushlow, C., Doyle, H. & Levines, M. Characterization localization of the even-skipped protein of Drosophila. EMBO J. 6, 749-759 (1987).
14. Kispert, A., Herrmann, B. G., Leptin, M. & Reuter, R. Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. Genes Dev. 8, 2137-2150 (1994).
15. Singer, J. B., Harbecke, R., Kusch, T., Reuter, R. & Lengyel, J. A. Drosophila brachyenteron regulates gene activity and morphogenesis in the gut. Development 122, 3703-3718 (1996).
16. Nusslein-Volhard, C., Kluding, H. & Jurgens, G. Genes affecting the segmental subdivisions of the Drosophila embryo. Cold Spring Harch Symp. Quant. Biol. 50, 145-154 (1983).
17. Sanchez-Herrero, E., Vernos, I., Marco, R. & Morata, G. Genetic organization of the Drosophila bithorax complex. Nature 313, 108-113 (1983).
18. Lecuit, T. & Cohen, S. M. Proximal-distal axis formation in the Drosophila leg. Nature 388, 139-145 (1997).
19. Brand, A. H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415 (1993).
20. Diaz-Benjumea, F. J., Cohen, B. & Cohen, S. M. Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs. Nature 372, 175-179 (1994).
21. Alexandre, C., Jacinto, A. & Ingham, P. W. Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the Cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes Dev. 10, 2003-2013 (1996).
22. van den Heuvel, M. & Ingham, P. W. smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 382, 547-551 (1996).
23. Chawengsaksophak, K., James, R., Hammond, V. E., Kontgen, F. & Beck, F. Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 396, 84-87 (1997).
24. Miller, D. J. & Miles, A. Homeobox genes and the zootype. Nature 365, 215-216 (1993).
25. Sánchez, L. Casares, F., Gorfinkiel, N. & Guerrero, I. The genital disc of Drosophila melanogaster. II. Role of the genes hedgehog, decapentaplegic and wingless. Dev. Genes Evol. 207, 229-241 (1997).
26. Murakami, R. et al. aproctous, a locus that is necessary for the development of the proctodeum in Drosophila embryos, encodes a homolog of the vertebrate Brachyury gene. Wilhelm Roux Arch. Dev. Biol. 205, 89-96 (1995).
27. Gorfinkiel, N., Morata, G. & Guerrero, I. The homeobox gene Distal-less induces ventral appendage development in Drosophila. Genes Dev. 11, 2259-2271 (1997).
28. Diaz-Benjumea, F. & Cohen, S. M. Serrate signals through Notch to establish a wingless-dependent organizer at the dorsal-ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225 (1995).