Synthesis of 2,6-dioxo-(1H,3H)-9-n-ribitylpurine and 2,6-dioxo-(1H,3H)- 8-aza-9-N-ribitylpurine as inhibitors of lumazine synthase and ribofiavin synthase

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 4, 1998, Pages 409-415

  Cushman, Mark ^a   Mavandadi, Farahnaz ^a   Kugelbrey, Karl ^b   Bacher, Adelbert ^b  

^a PURDUE UNIVERSITY   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Inhibition; Lumazine synthase; Riboflavin synthase

Indexed keywords

2,6 DIOXO (1H,3H) 8 AZA 9 N RIBITYLPURINE; 2,6 DIOXO (1H,3H) 9 N RIBITYLPURINE; ENZYME INHIBITOR; LUMAZINE; RIBOFLAVIN SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI;

BACILLUS SUBTILIS; ESCHERICHIA COLI; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; PURINES; RIBITOL; RIBOFLAVIN SYNTHASE;

BACILLUS SUBTILIS; ESCHERICHIA; ESCHERICHIA COLI;

EID: 0032054460     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00013-3     Document Type: Article

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