Identification by polymerase chain reaction of the G protein-coupled receptor kinases expressed in the mouse gonadotropic αT3-1 cell line

Endocrinology

Volumn 137, Issue 9, 1996, Pages 3942-3947

  Neill, Jimmy D ^a   Musgrove, Lois C ^a   Sellers, Jeffrey C ^a   Duck, L Wayne ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GONADORELIN RECEPTOR; GONADOTROPIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; PHOSPHOTRANSFERASE; RECEPTOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME POLYMORPHISM; GONADOTROPIN SECRETING CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SEQUENCE HOMOLOGY;

EID: 0029815762     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.9.8756570     Document Type: Article

References (30)

1. Smith MA, Vale WW 1981 Desensitization to gonadotropin-releasing hormone observed in superfused pituitary cells on Cytodex beads. Endocrinology 108:752-759
2. Cassina MP, Grantham KD, Neill JD, A new mode of GnRH-induced desensitization of LH secretion. Program of the 10th International Congress of Endocrinology, San Francisco CA, 1996, p 813 (Abstract P3-234)
3. Weiss J, Cote CR, Jameson JL, Crowley WFJ 1995 Homologous desensitization of gonadotropin-releasing hormone (GnRH)-stimnlated luteinizing hormone secretion in vitro occurs within the duration of an endogenous GnRH pulse. Endocrinology 136:138-143
4. Hausdorff WP, Caron MG, Lefkowitz RJ 1990 Turning off the signal: desensitization of β-adrenergic receptor function. FASEB J 4:2881-2889
5. Wojcikiewicz RJH, Tobin AB, Nahorski SR 1993 Desensitization of cell signalling mediated by phosphoinositidase C. Trends Pharmacol Sci 14:279-285
6. Inglese J, Freedman NJ, Koch WJ, Lefkowitz RJ 1993 Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem 268:23735-23738
7. Conn PM 1994 The molecular mechanism of gonadotropin-releasing hormone action in the pituitary. In: Knobil E, Neill JD (eds) The Physiology of Reproduction, ed 2. Raven Press, New York, pp 1815-1832
8. Hawes BE, Marzen JE, Waters SB, Conn PM 1992 Sodium fluoride provokes gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and gonadotrope sensitization to A23187: evidence for multiple G proteins in GnRH action. Endocrinology 130:2465-2475
9. Loumaye E, Catt KJ 1983 Agonist-induced regulation of pituitary receptors for gonadotropin-releasing hormone. Dissociation of receptor recruitment from hormone release in cultured gonadotrophs. J Biol Chem 258:12002-12009
10. 2+ levels. Mol Pharmacol 25:51-55
11. Stojilkovic SS, Reinhart J, Catt KJ 1994 Gonadotropin-releasing hormone receptors: structure and signal transduction pathways. Endocr Rev 15:462-499
12. Tsuga H, Kaemeyama K, Haga T, Kurose H, Nagao T 1994 Sequestration of muscarinic acetylcholine receptors m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2. J Biol Chem 269:32522-32527
13. Ferguson SS, Menard L, Barak LS, Koch WJ, Colapietro AM, Caron MG 1995 Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1. J Biol Chem 270:24782-24789
14. Ferguson SS, Downey WEI, Colapietro AM, Barak LS, Menard L, Caron MG 1996 Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271:363-366
15. Benovic JL, Onorato JJ, Arriza JL, Stone WC, Lohse M, Jenkins NA, Gilbert DJ, Copeland NG, Caron MG, Lefkowitz RJ 1991 Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family. J Biol Chem 266:14939-14946
16. Haribabu B, Snyderman R 1993 Identification of additional members of human G-protein-coupled receptor kinase multigene family. Proc Natl Acad Sci USA 90:9398-9402
17. Horn F, Bilezikjian LM, Perrin MH, Bosma MM, Windle JJ, Huber KS, Blount AL, Hille B, Vale W, Mellon PL 1991 Intracellular responses to gonadotropin-releasing hormone in a clonal cell line of the gonadotrope lineage. Mol Endocrinol 5:347-355
18. Smith PF, Luque EH, Neill JD 1986 Detection and measurement of secretion from individual neuroendocrine cells using a reverse hemolytic plaque assay. Methods Enzymol 124:443-465
19. Barnes WM 1992 The fidelity of Taq polymerase catalyzing PCR is improved by an N-terminal deletion. Gene 112:29-35
20. Houben H, Denef C 1994 Bioactive peptides in anterior pituitary cells. Peptides 15:547-582
21. Kirillova J, Several neuromodulators regulate pituitary gonadotropes. Program of the 77th Annual Meeting of the Endocrine Society, Washington DC, 1995, p 305 (Abstract P2-59)
22. Premont RT, Inglese J, Lefkowitz RJ 1995 Protein kinases that phosphorylate activated G protein-coupled receptors. FASEB J 9:175-182
23. Zheng L, Slojilkovic SS, Hunyady L, Krsmanovic LZ, Catt KJ 1994 Sequential activation of phospholipase-C and -D in agonist-stimulated gonadotrophs. Endocrinology 134:1446-1454
24. Davidson JS, Wakefield IK, Millar RP 1994 Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor. Biochem J 300:299-302
25. McArdle CA, Forrest-Owen W, Willars G, Davidson J, Poch A, Kratzmeier A 1995 Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived αT3-1 cell line. Endocrinology 136:4864-4871
26. Anderson L, McGregor A, Cook JV, Chilvers E, Eidne KA 1995 Rapid desensitization of GnRH-stimulated intracellular signaling events in αT3-1 and HEK-293 cells expressing the GnRH receptor. Endocrinology 136:5228-5231
27. Anderson L, Milligan G, Eidne KA 1993 Characterization of the gonadotrophin-releasing hormone receptor in αT3-1 pituitary gonadotroph cells. J Endocrinol 136:51-58
28. Neill JD, Sellers JC, Duck LW, Musgrove LC, Rapid desensitization of GnRH-induced phospholipase C activity in cells heterologously expressing the GnRH receptor. Program of the 10th International Congress of Endocrinology, San Francisco CA, 1996, p 812 (Abstract P3-229)
29. Mason DR, Arora KK, Mertz LM, Catt KJ 1994 Homologous down-regulation of gonadotropin-releasing hormone receptor sites and messenger ribonucleic acid transcipts in α-T3-1 cells. Endocrinology 135:1165-1170
30. Zhou W, Rodic V, Kitanovic S, Flanagan CA, Chi L, Weinstein H, Maayani S, Millar RP, Sealfon SC 1995 A locus of the gonadotropin-releasing hormone receptor that differentiates agonist and antagonist binding sites. J Biol Chem 270:18853-18857