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Volumn 257, Issue 1, 1999, Pages 177-190

Antigenic heterogeneity of the hepatitis C virus NS4 protein as modeled with synthetic peptides

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; PEPTIDE; PROTEIN;

EID: 0033602560     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9612     Document Type: Article
Times cited : (17)

References (52)
  • 6
    • 0028945033 scopus 로고
    • Genetic heterogeneity of hepatitis C virus: Quasispecies and genotypes
    • Bukh J., Miller R. H., Purcell R. H. Genetic heterogeneity of hepatitis C virus: Quasispecies and genotypes. Semin. Liver Dis. 15:1995;41-63.
    • (1995) Semin. Liver Dis. , vol.15 , pp. 41-63
    • Bukh, J.1    Miller, R.H.2    Purcell, R.H.3
  • 7
    • 0026094311 scopus 로고
    • Identification of an immunodominant B cell epitope on the hepatitis C virus nonstructural region defined by human monoclonal antibodies
    • Cerino A., Mondelli M. U. Identification of an immunodominant B cell epitope on the hepatitis C virus nonstructural region defined by human monoclonal antibodies. J. Immunol. 147:1991;2692-2696.
    • (1991) J. Immunol. , vol.147 , pp. 2692-2696
    • Cerino, A.1    Mondelli, M.U.2
  • 8
    • 0030928381 scopus 로고    scopus 로고
    • Complete nucleotide sequence of a type 4 hepatitis C virus variant, the predominant genotype in the Middle East
    • Chamberlain R. W., Adams N., Saeed A. A., Simmonds P., Elliott R. M. Complete nucleotide sequence of a type 4 hepatitis C virus variant, the predominant genotype in the Middle East. J. Gen. Virol. 78:1997;1341-1347.
    • (1997) J. Gen. Virol. , vol.78 , pp. 1341-1347
    • Chamberlain, R.W.1    Adams, N.2    Saeed, A.A.3    Simmonds, P.4    Elliott, R.M.5
  • 10
    • 0025840533 scopus 로고
    • Serological responses to infection with three different types of hepatitis C virus
    • Chan S. W., Simmonds P., McOmish F., Yap P. L., Mitchell R., Dow B., Follett E. Serological responses to infection with three different types of hepatitis C virus. Lancet. 338:1991;1391.
    • (1991) Lancet , vol.338 , pp. 1391
    • Chan, S.W.1    Simmonds, P.2    McOmish, F.3    Yap, P.L.4    Mitchell, R.5    Dow, B.6    Follett, E.7
  • 12
    • 0028609468 scopus 로고
    • Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C
    • Chayama K., Tsubota A., Koida I., Arase Y., Saitoh S., Ikeda K., Kumada K. Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C. J. Gen. Virol. 75:1994;3623-3628.
    • (1994) J. Gen. Virol. , vol.75 , pp. 3623-3628
    • Chayama, K.1    Tsubota, A.2    Koida, I.3    Arase, Y.4    Saitoh, S.5    Ikeda, K.6    Kumada, K.7
  • 13
    • 0025853326 scopus 로고
    • Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus
    • Chiba J., Ohba H., Matsuura Y., Atanabe Y., Katayama T., Kikuchi S., Saito I., Miyamura T. Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus. Proc. Natl. Acad. Sci. USA. 88:1991;4641-4645.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4641-4645
    • Chiba, J.1    Ohba, H.2    Matsuura, Y.3    Atanabe, Y.4    Katayama, T.5    Kikuchi, S.6    Saito, I.7    Miyamura, T.8
  • 14
    • 0026448768 scopus 로고
    • Diagnosis of hepatitis C virus (HCV) infection using an immunodominant chimeric polyprotein to capture circulating antibodies: Reevaluation of the role of HCV in liver disease
    • Chien D. Y., Choo O. L., Tabrizi A., Kuo C., McFarland J., Berger K., Lee C., Shuster J. R., Nguyen T., Moyer D. L. Diagnosis of hepatitis C virus (HCV) infection using an immunodominant chimeric polyprotein to capture circulating antibodies: Reevaluation of the role of HCV in liver disease. Proc. Natl. Acad. Sci. USA. 89:1992;10011-10015.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10011-10015
    • Chien, D.Y.1    Choo, O.L.2    Tabrizi, A.3    Kuo, C.4    McFarland, J.5    Berger, K.6    Lee, C.7    Shuster, J.R.8    Nguyen, T.9    Moyer, D.L.10
  • 15
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo Q., Kuo G., Weiner A., Overby L., Bradley D., Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 244:1989;359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.1    Kuo, G.2    Weiner, A.3    Overby, L.4    Bradley, D.5    Houghton, M.6
  • 18
    • 84989559703 scopus 로고
    • Hepatitis C virus genotypes: An investigation of type-specific differences in geographic origin and disease
    • Dusheiko G., Schmilovitz-Weiss H., Brown D., McOmish F., Yap P. L., Sherlock S. Hepatitis C virus genotypes: An investigation of type-specific differences in geographic origin and disease. Hepatology. 19:1994;13-18.
    • (1994) Hepatology , vol.19 , pp. 13-18
    • Dusheiko, G.1    Schmilovitz-Weiss, H.2    Brown, D.3    McOmish, F.4    Yap, P.L.5    Sherlock, S.6
  • 19
    • 0027476809 scopus 로고
    • Expression and identification of hepatitis C virus polyprotein cleavage products
    • Grakoui A., Wychowski C., Lin C., Feinstone S. M., Rice C. Expression and identification of hepatitis C virus polyprotein cleavage products. J. Virol. 67:1993;1385-1395.
    • (1993) J. Virol. , vol.67 , pp. 1385-1395
    • Grakoui, A.1    Wychowski, C.2    Lin, C.3    Feinstone, S.M.4    Rice, C.5
  • 20
    • 0025991559 scopus 로고
    • Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
    • Hijikata M., Kato N., Ootsuyama Y., Nakagawa M., Shimotohno K. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl. Acad. Sci. USA. 88:1991;5547-5551.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5547-5551
    • Hijikata, M.1    Kato, N.2    Ootsuyama, Y.3    Nakagawa, M.4    Shimotohno, K.5
  • 21
    • 0025735590 scopus 로고
    • Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein
    • Hosein B., Fang C. T., Popovsky M. A., Ye J., Zhang M., Wang C. Y. Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein. Proc. Natl. Acad. Sci. USA. 88:1991;3647-3651.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3647-3651
    • Hosein, B.1    Fang, C.T.2    Popovsky, M.A.3    Ye, J.4    Zhang, M.5    Wang, C.Y.6
  • 22
    • 0025862146 scopus 로고
    • Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease
    • Houghton M., Weiner A., Han J. Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease. Hepatology. 14:1991;381-388.
    • (1991) Hepatology , vol.14 , pp. 381-388
    • Houghton, M.1    Weiner, A.2    Han, J.3
  • 23
    • 0026793858 scopus 로고
    • Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases
    • Inoue Y., Suzuki R., Matsuura Y., Harda S., Chiba J., Eatanabe Y., Saito I., Miyamura T. Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases. J. Gen. Virol. 73:1992;2151-2154.
    • (1992) J. Gen. Virol. , vol.73 , pp. 2151-2154
    • Inoue, Y.1    Suzuki, R.2    Matsuura, Y.3    Harda, S.4    Chiba, J.5    Eatanabe, Y.6    Saito, I.7    Miyamura, T.8
  • 25
    • 0028872981 scopus 로고
    • Linear B-cell epitopes of the NS3-NS4-NS5 proteins of the hepatitis C virus as modeled with synthetic peptides
    • Khudyakov Y. E., Khudyakova N. S., Jue D. L., Lambert S. B., Fang S., Fields H. A. Linear B-cell epitopes of the NS3-NS4-NS5 proteins of the hepatitis C virus as modeled with synthetic peptides. Virology. 206:1995;666-672.
    • (1995) Virology , vol.206 , pp. 666-672
    • Khudyakov, Y.E.1    Khudyakova, N.S.2    Jue, D.L.3    Lambert, S.B.4    Fang, S.5    Fields, H.A.6
  • 27
  • 28
    • 0027509074 scopus 로고
    • Detection of three types of hepatitis C virus in blood donors: Investigation of type-specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities
    • McOmish F., Chan S. W., Dow B. C., Gillon J., Frame W. D., Crawford R. J., Yap P. L., Follett E. A. C., Simmonds P. Detection of three types of hepatitis C virus in blood donors: Investigation of type-specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities. Transfusion. 33:1993;7-13.
    • (1993) Transfusion , vol.33 , pp. 7-13
    • McOmish, F.1    Chan, S.W.2    Dow, B.C.3    Gillon, J.4    Frame, W.D.5    Crawford, R.J.6    Yap, P.L.7    Follett, E.A.C.8    Simmonds, P.9
  • 30
    • 0025249362 scopus 로고
    • Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus subgroups
    • Miller R. H., Purcell R. H. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus subgroups. Proc. Natl. Acad. Sci. USA. 87:1990;2059-2061.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2059-2061
    • Miller, R.H.1    Purcell, R.H.2
  • 31
    • 0026599877 scopus 로고
    • Serodiagnostic assay of hepatitis C virus infection using viral protease expressed inEscherichia coli
    • Mori S., Ohkoshi S., Hijikata M., Kato N., Shimotohno K. Serodiagnostic assay of hepatitis C virus infection using viral protease expressed inEscherichia coli. Jpn. J. Cancer Res. 83:1992;264-268.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 264-268
    • Mori, S.1    Ohkoshi, S.2    Hijikata, M.3    Kato, N.4    Shimotohno, K.5
  • 33
    • 0027265404 scopus 로고
    • Genotype dependence of hepatitis C virus antibodies detectable by the first-generation enzyme-linked immunosorbent assay with C 100-3 protein
    • Nagayama R., Tsuda F., Okamoto H., Wang Y., Mitsui T., Tanaka T., Miyakawa Y., Mayumi M. Genotype dependence of hepatitis C virus antibodies detectable by the first-generation enzyme-linked immunosorbent assay with C 100-3 protein. J. Clin. Invest. 92:1993;1529-1533.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1529-1533
    • Nagayama, R.1    Tsuda, F.2    Okamoto, H.3    Wang, Y.4    Mitsui, T.5    Tanaka, T.6    Miyakawa, Y.7    Mayumi, M.8
  • 34
    • 0025954714 scopus 로고
    • Identification of an immunodominant epitope within the capsid protein of hepatitis C virus
    • Nasoff M. S., Zebedee S. L., Inchauspe G., Prince A. M. Identification of an immunodominant epitope within the capsid protein of hepatitis C virus. Proc. Natl. Acad. Sci. USA. 88:1991;5462-5466.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5462-5466
    • Nasoff, M.S.1    Zebedee, S.L.2    Inchauspe, G.3    Prince, A.M.4
  • 36
    • 0026751054 scopus 로고
    • Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: Comparative study of four distinct genotypes
    • Okamoto H., Kurai K., Okada S.-I., Yamamoto K., Lizuka H., Tanaka T., Fukuda S., Tsuda F., Mishiro S. Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: Comparative study of four distinct genotypes. Virology. 188:1992;331-341.
    • (1992) Virology , vol.188 , pp. 331-341
    • Okamoto, H.1    Kurai, K.2    Okada, S.-I.3    Yamamoto, K.4    Lizuka, H.5    Tanaka, T.6    Fukuda, S.7    Tsuda, F.8    Mishiro, S.9
  • 39
    • 0026689290 scopus 로고
    • Immunodominant regions within the hepatitis C virus core and putative matrix proteins
    • Sallberg M., Ruden U., Wahren B., Magnius L. O. Immunodominant regions within the hepatitis C virus core and putative matrix proteins. J. Clin. Microbiol. 30:1992;1989-1994.
    • (1992) J. Clin. Microbiol. , vol.30 , pp. 1989-1994
    • Sallberg, M.1    Ruden, U.2    Wahren, B.3    Magnius, L.O.4
  • 40
    • 0028905430 scopus 로고
    • Variability of hepatitis C virus
    • Simmonds P. Variability of hepatitis C virus. Hepatology. 21:1995;570-583.
    • (1995) Hepatology , vol.21 , pp. 570-583
    • Simmonds, P.1
  • 42
    • 0027193025 scopus 로고
    • Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): Use of type-specific peptides to serologically differentiate infections with HCV types 1, 2, and 3
    • Simmonds P., Rose K. A., Graham S., Chan S.-W., McOmish F., Dow B. C., Follett E. A. C., Yap P. L., Marsden H. Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): Use of type-specific peptides to serologically differentiate infections with HCV types 1, 2, and 3. J. Clin. Microbiol. 31:1993b;1493-1503.
    • (1993) J. Clin. Microbiol. , vol.31 , pp. 1493-1503
    • Simmonds, P.1    Rose, K.A.2    Graham, S.3    Chan, S.-W.4    McOmish, F.5    Dow, B.C.6    Follett, E.A.C.7    Yap, P.L.8    Marsden, H.9
  • 43
    • 0027968519 scopus 로고
    • Cloning and phylogenetic analysis of the core, E2, and NS3/NS4 regions of the hepatitis C virus type 5a
    • Stuyver L., Van Arnhem W., Wyseur A., Maertens G. Cloning and phylogenetic analysis of the core, E2, and NS3/NS4 regions of the hepatitis C virus type 5a. Biochem. Biophys. Res. Commun. 202:1994;1308-1314.
    • (1994) Biochem. Biophys. Res. Commun. , vol.202 , pp. 1308-1314
    • Stuyver, L.1    Van Arnhem, W.2    Wyseur, A.3    Maertens, G.4
  • 45
    • 0025667078 scopus 로고
    • The putative nucleocapsid and envelope protein genes of hepatitis C virus determined by comparison of the nucleotide sequences of two isolates derived from an experimentally infected chimpanzee and healthy human carriers
    • Takeuchi K., Kubo Y., Boonmar Y., Waranabe Y., Katayama T., Choo Q. L., Kuo G., Houghton M., Saito E., Miyamura T. The putative nucleocapsid and envelope protein genes of hepatitis C virus determined by comparison of the nucleotide sequences of two isolates derived from an experimentally infected chimpanzee and healthy human carriers. J. Gen. Virol. 71:1990;3027-3033.
    • (1990) J. Gen. Virol. , vol.71 , pp. 3027-3033
    • Takeuchi, K.1    Kubo, Y.2    Boonmar, Y.3    Waranabe, Y.4    Katayama, T.5    Choo, Q.L.6    Kuo, G.7    Houghton, M.8    Saito, E.9    Miyamura, T.10
  • 47
    • 0032486470 scopus 로고    scopus 로고
    • Characterization of a linear epitope in the nonstructural region 4 of hepatitis C virus with reactivity to seroconversion antibodies
    • Wienhues U., Ihlenfeldt H.-G., Seidel C., Schmitt U., Kraas W., Jung G. Characterization of a linear epitope in the nonstructural region 4 of hepatitis C virus with reactivity to seroconversion antibodies. Virology. 245:1998;281-288.
    • (1998) Virology , vol.245 , pp. 281-288
    • Wienhues, U.1    Ihlenfeldt, H.-G.2    Seidel, C.3    Schmitt, U.4    Kraas, W.5    Jung, G.6
  • 48
    • 0026768604 scopus 로고
    • Antibodies to a putative hepatitis C virus polyprotein in Japanese patients with chronic liver disease
    • Yuki N., Hayashi N., Kasahara A., Hagiwara H., Ueda K., Fusamoto H., Kamada T. Antibodies to a putative hepatitis C virus polyprotein in Japanese patients with chronic liver disease. J. Med. Virol. 38:1992;86-91.
    • (1992) J. Med. Virol. , vol.38 , pp. 86-91
    • Yuki, N.1    Hayashi, N.2    Kasahara, A.3    Hagiwara, H.4    Ueda, K.5    Fusamoto, H.6    Kamada, T.7
  • 49
    • 0031060053 scopus 로고    scopus 로고
    • Indeterminate results of the second-generation hepatitis C virus (HCV) recombinant immunoblot assay: Significance of high-level c22-3 reactivity and influence of HCV genotypes
    • Zein N. N., Germer J. J., Wendt N. K., Schimek C. M., Thorvilson J. N., Mitchell P. S., Persing D. H. Indeterminate results of the second-generation hepatitis C virus (HCV) recombinant immunoblot assay: Significance of high-level c22-3 reactivity and influence of HCV genotypes. J. Clin. Microbiol. 35:1997;311-312.
    • (1997) J. Clin. Microbiol. , vol.35 , pp. 311-312
    • Zein, N.N.1    Germer, J.J.2    Wendt, N.K.3    Schimek, C.M.4    Thorvilson, J.N.5    Mitchell, P.S.6    Persing, D.H.7
  • 50
    • 0029028308 scopus 로고
    • Genotype-dependent serologic reactivities patients infected with hepatitis C virus in the United States
    • Zein N. N., Rakela J., Persin D. H. Genotype-dependent serologic reactivities patients infected with hepatitis C virus in the United States. Mayo Clin. Proc. 70:1995;449-452.
    • (1995) Mayo Clin. Proc. , vol.70 , pp. 449-452
    • Zein, N.N.1    Rakela, J.2    Persin, D.H.3
  • 51
    • 0028426932 scopus 로고
    • Antigenic structure of the complete nonstructural NS2 and NS5 proteins of hepatitis C virus (HCV): Anti-HCV NS2 and NS5 antibody reactivities in relation to HCV serotype, presence of HCV RNA, and acute HCV infection
    • Zhang Z. X., Chen M., Sonnerborg A., Sallberg M. Antigenic structure of the complete nonstructural NS2 and NS5 proteins of hepatitis C virus (HCV): Anti-HCV NS2 and NS5 antibody reactivities in relation to HCV serotype, presence of HCV RNA, and acute HCV infection. Clin. Diagn. Lab. Immunol. 1:1994;290-294.
    • (1994) Clin. Diagn. Lab. Immunol. , vol.1 , pp. 290-294
    • Zhang, Z.X.1    Chen, M.2    Sonnerborg, A.3    Sallberg, M.4
  • 52
    • 0028955218 scopus 로고
    • Evaluation of a multiple peptide assay for typing of antibodies to the hepatitis C virus: Relation to genomic typing by the polymerase chain reaction
    • Zhang Z. X., Yun Z., Chen M., Sonnerborg A., Sallberg M. Evaluation of a multiple peptide assay for typing of antibodies to the hepatitis C virus: Relation to genomic typing by the polymerase chain reaction. J. Med. Virol. 45:1995;50-55.
    • (1995) J. Med. Virol. , vol.45 , pp. 50-55
    • Zhang, Z.X.1    Yun, Z.2    Chen, M.3    Sonnerborg, A.4    Sallberg, M.5


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