-
1
-
-
0000191854
-
-
(Ed.: S. Patai), John Wiley, New York
-
1. J.-A. Gautier, M. Miocque, C. C. Farnoux in The Chemistry of Amidines and Imidates, Vol. I (Ed.: S. Patai), John Wiley, New York, 1975, pp. 283-348; G. V. Boyd in The Chemistry of Amidines and Imidates, Vol. 2 (Eds.: S. Patai, Z. Rappoport), John Wiley, New York, 1991, pp. 367-424.
-
(1975)
The Chemistry of Amidines and Imidates, Vol. I
, vol.1
, pp. 283-348
-
-
Gautier, J.-A.1
Miocque, M.2
Farnoux, C.C.3
-
2
-
-
0001763484
-
-
(Eds.: S. Patai, Z. Rappoport), John Wiley, New York
-
1. J.-A. Gautier, M. Miocque, C. C. Farnoux in The Chemistry of Amidines and Imidates, Vol. I (Ed.: S. Patai), John Wiley, New York, 1975, pp. 283-348; G. V. Boyd in The Chemistry of Amidines and Imidates, Vol. 2 (Eds.: S. Patai, Z. Rappoport), John Wiley, New York, 1991, pp. 367-424.
-
(1991)
The Chemistry of Amidines and Imidates, Vol. 2
, vol.2
, pp. 367-424
-
-
Boyd, G.V.1
-
3
-
-
0027243533
-
-
2. a) From microbial broth of Pseudomonas fluorescens: T. Hida, S. Tsubotani, Y. Funabashi, H. Ono, S. Harada, Bull. Chem. Soc. Jpn. 1993, 66, 863-869;
-
(1993)
Bull. Chem. Soc. Jpn.
, vol.66
, pp. 863-869
-
-
Hida, T.1
Tsubotani, S.2
Funabashi, Y.3
Ono, S.4
Harada, S.5
-
5
-
-
0021808470
-
-
c) from Brunfelsia grandiflora D: H. A. Lloyd, H. M. Fales, M. E. Goldman, D. M. Jerina, T. Plowman, R. E. Schultes, Tetrahedron Lett. 1985, 26, 2623;
-
(1985)
Tetrahedron Lett.
, vol.26
, pp. 2623
-
-
Lloyd, H.A.1
Fales, H.M.2
Goldman, M.E.3
Jerina, D.M.4
Plowman, T.5
Schultes, R.E.6
-
6
-
-
0001486546
-
-
d) from Streptomyces distallicus: F. Arcamone, P. G. Orezzi, W. Barbieri, V. Nicolella, S. Penco, Gazz. Chim. Ital. 1967, 97, 1097-1109;
-
(1967)
Gazz. Chim. Ital.
, vol.97
, pp. 1097-1109
-
-
Arcamone, F.1
Orezzi, P.G.2
Barbieri, W.3
Nicolella, V.4
Penco, S.5
-
8
-
-
0343598982
-
-
f) from Streptomyces: S. Nakamura, K. Karasawa, H. Yonehara, N. Tanaka, H. Um, J. Antibiot. Ser. A 1961, 14, 103-107;
-
(1961)
J. Antibiot. Ser. A
, vol.14
, pp. 103-107
-
-
Nakamura, S.1
Karasawa, K.2
Yonehara, H.3
Tanaka, N.4
Um, H.5
-
10
-
-
4243266377
-
-
US 2804463
-
h) from microbial broth of Nocardia formica: US 2804463 1956 [Chem. Abstr. 1958, 52, 8474e].
-
(1956)
Chem. Abstr.
, vol.52
-
-
-
14
-
-
0009698224
-
-
4. a) H. Henecka, P. Kurtz, Methoden Org. Chem. (Houben-Weyl), 4th ed. 1952, Vol. 8, 702-706;
-
(1952)
Methoden Org. Chem. (Houben-Weyl), 4th Ed.
, vol.8
, pp. 702-706
-
-
Henecka, H.1
Kurtz, P.2
-
17
-
-
0001311980
-
-
(Ed.: I. O. Sutherland), Pergamon Press, Oxford, New York, Toronto, Sydney, Frankfurt
-
d) G. Tennant in Comp. Org. Chem., Vol. 2 (Ed.: I. O. Sutherland), Pergamon Press, Oxford, New York, Toronto, Sydney, Frankfurt 1979, pp. 385-590;
-
(1979)
Comp. Org. Chem., Vol. 2
, vol.2
, pp. 385-590
-
-
Tennant, G.1
-
19
-
-
0000582505
-
-
(Eds.: S. Patai, Z. Rappoport), John Wiley, New York
-
f) G. V. Boyd in The Chemistry of Amidines and Imidates, Vol. 2 (Eds.: S. Patai, Z. Rappoport), John Wiley, New York, 1991, pp. 339-366;
-
(1991)
The Chemistry of Amidines and Imidates, Vol 2
, vol.2
, pp. 339-366
-
-
Boyd, G.V.1
-
20
-
-
0000455369
-
-
(Eds.: A. R. Katrizky, O. Meth-Cohn, C. W. Rees), Elsevier, Oxford
-
g) P. J. Dunn in Compr. Org. Funct. Group Transform., Vol. 5 (Eds.: A. R. Katrizky, O. Meth-Cohn, C. W. Rees), Elsevier, Oxford, 1995, pp. 741-782.
-
(1995)
Compr. Org. Funct. Group Transform., Vol. 5
, vol.5
, pp. 741-782
-
-
Dunn, P.J.1
-
21
-
-
85172378617
-
-
5. a) A. Pinner, Ber. 1885, 18, 2845-2852;
-
(1885)
Ber.
, vol.18
, pp. 2845-2852
-
-
Pinner, A.1
-
22
-
-
0029945361
-
-
b) H. U. Stilz, B. Jablonka, M. Just, J. Knolle, E. F. Paulus, G. Zoller, J. Med. Chem. 1996, 39, 2118-2122.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 2118-2122
-
-
Stilz, H.U.1
Jablonka, B.2
Just, M.3
Knolle, J.4
Paulus, E.F.5
Zoller, G.6
-
24
-
-
0000287332
-
-
7. a) P. L. Barker, P. L. Gendler, H. Rappoport, J. Org. Chem. 1981, 46, 2455-2465;
-
(1981)
J. Org. Chem.
, vol.46
, pp. 2455-2465
-
-
Barker, P.L.1
Gendler, P.L.2
Rappoport, H.3
-
25
-
-
0042597428
-
-
b) Y. Nil, K. Okano, S. Kobayashi, M. Ohno, Tetrahedron Lett. 1979, 20, 2517-2520.
-
(1979)
Tetrahedron Lett.
, vol.20
, pp. 2517-2520
-
-
Nil, Y.1
Okano, K.2
Kobayashi, S.3
Ohno, M.4
-
26
-
-
0021344836
-
-
8. P. C. Srivastava, G. R. Revankar, R. K. Robins, J. Med. Chem. 1984, 27, 266-269.
-
(1984)
J. Med. Chem.
, vol.27
, pp. 266-269
-
-
Srivastava, P.C.1
Revankar, G.R.2
Robins, R.K.3
-
27
-
-
0028822273
-
-
9. a) H. Jendralla, B. Seuring, J. Herchen, B. Kulitzscher, J. Wunner, W. Stüber, R. Koschinsky, Tetrahedron 1995, 51, 12047-12068;
-
(1995)
Tetrahedron
, vol.51
, pp. 12047-12068
-
-
Jendralla, H.1
Seuring, B.2
Herchen, J.3
Kulitzscher, B.4
Wunner, J.5
Stüber, W.6
Koschinsky, R.7
-
28
-
-
0029803790
-
-
b) B. D. Judkins, D. G. Allen, T. A. Cook, B. Evans, T. A. Sardharwala, Synth. Commun. 1996, 26, 4351-4367.
-
(1996)
Synth. Commun.
, vol.26
, pp. 4351-4367
-
-
Judkins, B.D.1
Allen, D.G.2
Cook, T.A.3
Evans, B.4
Sardharwala, T.A.5
-
30
-
-
4243213554
-
-
(Nissan), JP 042823256
-
b) (Nissan), JP 042823256, 1992, [Chem. Abstr. 1993, 118, 191356h].
-
(1992)
Chem. Abstr.
, vol.118
-
-
-
31
-
-
0029001871
-
-
11. R. E. Bolton, S. J. Coote, H. Finch, A. Lowdon, N. Pegg, M. V. Vinader, Tetrahedron Lett. 1995, 36, 4471-4474.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 4471-4474
-
-
Bolton, R.E.1
Coote, S.J.2
Finch, H.3
Lowdon, A.4
Pegg, N.5
Vinader, M.V.6
-
34
-
-
0000018867
-
-
c) C. Soula, A. Marsura, C. Luu-Duc, J. Pharm. Belg. 1987, 42, 293-296.
-
(1987)
J. Pharm. Belg.
, vol.42
, pp. 293-296
-
-
Soula, C.1
Marsura, A.2
Luu-Duc, C.3
-
38
-
-
0028807750
-
-
b) R. A. Moss, W. Ma, D. C. Merrer, S. Xue, Tetrahedron Lett. 1995, 36, 8761;
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 8761
-
-
Moss, R.A.1
Ma, W.2
Merrer, D.C.3
Xue, S.4
-
39
-
-
0029054044
-
-
c) J. B. Kirby, N. A. van Dantzig, C. K. Chang, D. G. Nocera, Tetrahedron Lett. 1995, 36, 3477-3480.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 3477-3480
-
-
Kirby, J.B.1
Van Dantzig, N.A.2
Chang, C.K.3
Nocera, D.G.4
-
41
-
-
0009718307
-
-
note
-
17. N-Acetylcysteine is the active substance of ACC200° a fluidifying and mucolytic drug.
-
-
-
-
42
-
-
0001182323
-
-
18. H. Moser, A. Fliri, A. Steiger, G. Costello, J. Schreiber, A. Eschenmoser, Helv. Chim. Acta 1986, 69, 1224-1262. Note: In our hands the amidine synthesis described by Eschenmoser et al. starting from (N-Boc-alanyl)-aminoacetonitrile, using stoichiometric amounts of cysteine and ammonia as reagent only gave a 40:60 mixture of the desired product and the corresponding thiazoline carboxylic acid derivative (c.f. table 1, entry 10).
-
(1986)
Helv. Chim. Acta
, vol.69
, pp. 1224-1262
-
-
Moser, H.1
Fliri, A.2
Steiger, A.3
Costello, G.4
Schreiber, J.5
Eschenmoser, A.6
-
43
-
-
0025835284
-
-
19. Thiazoline carboxylic acid derivatives from nitriles and cysteine: a) H. J. Bergeron, J. Niegard, J. B. Dichs, M. Egli-Karmakka, J. Frei, A. Huxley-Tencer, H. H. Peter, J. Med. Chem. 1991, 34, 2072-2078;
-
(1991)
J. Med. Chem.
, vol.34
, pp. 2072-2078
-
-
Bergeron, H.J.1
Niegard, J.2
Dichs, J.B.3
Egli-Karmakka, M.4
Frei, J.5
Huxley-Tencer, A.6
Peter, H.H.7
-
44
-
-
0025255952
-
-
b) S. Kwiatkowski, P. J. Crocker, A. J. Chavan, N. Imai, B. E. Haley, D. S. Watt, Tetrahedron Lett. 1990, 31, 2093-2096;
-
(1990)
Tetrahedron Lett.
, vol.31
, pp. 2093-2096
-
-
Kwiatkowski, S.1
Crocker, P.J.2
Chavan, A.J.3
Imai, N.4
Haley, B.E.5
Watt, D.S.6
-
46
-
-
5644268779
-
-
20. H. Henecka, P. Kurtz, Methoden Org. Chem. (Houben-Weyl), 4th Ed. 1952, Vol. 8, p. 703.
-
(1952)
Methoden Org. Chem. (Houben-Weyl), 4th Ed. 1952
, vol.8
, pp. 703
-
-
Henecka, H.1
Kurtz, P.2
-
47
-
-
4244037172
-
-
WO 9809950, 1998
-
21. a) (BASF), WO 9809950, 1998 [Chem. Abstr. 1998, 128, 205140d];
-
(1998)
Chem. Abstr.
, vol.128
-
-
-
48
-
-
0009735569
-
-
note
-
b) The corresponding reaction of 4 with ammonia (50 bar) and without N-acetylcysteine gave no amidine 5 even after prolonged reaction time (80 h).
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