Characterization of protein release through glucose-sensitive hydrogel membranes

Biomaterials

Volumn 18, Issue 11, 1997, Pages 801-806

  Obaidat, Aiman A ^a   Park, Kinam ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Drug delivery; Glucose sensitive hydrogels; Insulin release; Sol gel phase reversible hydrogels

Indexed keywords

DIFFUSION IN SOLIDS; ENZYMES; GLUCOSE; HYDROGELS; INSULIN; POLYMERIC MEMBRANES; POROUS MATERIALS; SOL-GELS;

CONCANAVALIN A; HYDROGEL MEMBRANES; LYSOZYME; POLYHYDROXYETHYL METHACRYLATES;

CONTROLLED DRUG DELIVERY;

CONCANAVALIN A; GLUCOSE; INSULIN; LYSOZYME; POLYMACON;

ARTICLE; ARTIFICIAL MEMBRANE; HYDROGEL; INSULIN RELEASE; PRIORITY JOURNAL; PROTEIN SECRETION;

CONCANAVALIN A; DRUG CARRIERS; GLUCOSE; HYDROGEL; KINETICS; MEMBRANES, ARTIFICIAL; MURAMIDASE; PERMEABILITY; POLYETHYLENE GLYCOLS; POLYHYDROXYETHYL METHACRYLATE; PROTEINS; TIME FACTORS;

EID: 0031172661     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(96)00198-6     Document Type: Article

References (25)

1. Ranade, V. V. and Hollinger, M. A., Drug Delivery Systems. CRC Press, Boca Raton, FL, 1996.
2. Pitt, C. G., The controlled parentral delivery of polypeptides and proteins. Int. J. Pharm., 1990, 59, 173-196.
3. Brownlee, M. and Cerami, A., Glycosylated insulin complexed to concanavalin A. Biochemical basis for a closed-loop insulin delivery system. Diabetes, 1983, 32, 499-504.
4. Sawahata, K., Hara, M., Yasunaga, H. and Osada, Y., Electrically controlled drug delivery system using polyelectrolyte gels. J. Controlled Rel., 1990, 14, 253-262.
5. Morris, J. E., Hoffman, A. S. and Fisher, R. R., Affinity precipitation of proteins by polyligands. Biotech. Bioeng., 1993, 41, 991-997.
6. Nakamae, K., Miyata, T., Jikihara, A. and Hoffman, A. S., Formation of poly(glycosyloxyethyl methacrylate)-concanavalin A complex and its glucose sensitivity. J. Biomater. Sci. Polymer Edn., 1994, 6, 79-90.
7. Lee, S. J. and Park, K., Synthesis of sol-gel phase-reversible hydrogels sensitive to glucose. Proc. Intern. Symp. Control. Rel. Bioact. Mater., 1994, 21, 93-94.
8. Lee, S. J. and Park, K., Synthesis and characterization of sol-gel phase-reversible hydrogels sensitive to glucose. Polymer Preprints, 1994, 35, 391-392.
9. Taylor, M. J. and Adams, G. G., Insulin delivery using a novel glucose-sensitive formulation. Proc. Intern. Symp. Control. Rel. Bioact. Mater., 1995, 22, 746-747.
10. Miyata, T., Jikihara, A., Nakamae, K. and Hoffman, A. S., Preparation of poly(2-glucosyloxyethyl methacrylate)-concanavalin A complex hydrogel and its glucose sensitivity. Macromol. Chem. Phys., 1996, 197, 1135-1146.
11. Obaidat, A. A. and Park, K., Characterization of glucose-dependent gel-sol phase transition of the polymeric glucose-concanavalin A hydrogel system. Pharm. Res., 1996, 13, 989-995.
12. Lee, S. J. and Park, K., Synthesis and characterization of sol-gel phase-reversible hydrogels sensitive to glucose. J. Mol. Rec., in press.
13. Talley, E. A., Vale, M. D. and Yanovsky, E., Allyl ethers of carbohydrates. III. Ethers of glucose and galactose. J. Am. Chem. Soc., 1945, 67, 2037-2039.
14. Cunningham, B. A., Wan, G. J. L., Pflum, M. N. and Edelman, G. M., Isolation and proteolytic cleavage of the intact subunit of concanavalin A. Biochemistry, 1972, 11, 3233-3239.
15. Ronel, S. H., D'Andrea, M. J., Hashiguchi, H., Klomp, G. F. and Dobelle, W. H., Macroporous hydrogel membranes for a hybrid artificial pancreas. I. Synthesis and chamber fabrication. J. Biomed. Mater. Res., 1983, 17, 855-864.
16. Sato, S., Ebert, C. D. and Kim, S. W., Prevention of insulin self-association and surface adsorption. J. Pharm. Sci., 1983, 72, 228-232.
17. Dubois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A. and Smith, F., Colorimetric method for determination of sugars and related substances. Anal. Chem., 1956, 28, 350-355.
18. Uludag, H., Babensee, J. E., Roberts, T., Kharlip, L., Horvath, V. and Sefton, M. V., Controlled release of dopamine, insulin and other agents from microencapsulated cells. J. Controlled Rel., 1993, 24, 3-12.
19. Klomp, G. F., Hashiguchi, H., Ursell, P. C., Takeda, Y., Taguchi, T. and Dobelle, W. H., Macroporous hydrogel membranes for a hybrid artificial pancreas. II. Biocompatibility. J. Biomed. Mater. Res., 1983, 17, 865-871.
20. Jeong, S. Y., Kim, S. W., Holmberg, D. L. and McRea, J. C., Self-regulating insulin delivery systems. III. In vivo studies. J. Controlled Rel., 1985, 2, 143-152.
21. Sato, S., Jeong, S. Y., McRea, J. C. and Kim, S. W., Self-regulating insulin delivery systems. II. In vitro studies. J. Controlled Rel., 1984, 1, 67-77.
22. Beckert, W. H. and M. M., S., Mitogenic activity of the jack bean (Canavalia ensiformis) with rabbit peripheral blood lymphocytes. Int. Arch. Allergy Appl. Immunol., 1970, 30, 337-341.
23. Powell, A. E. and Leon, M. A., Reversible interaction of human lymphocytes with the mitogen concanavalin A. Exp. Cell Res., 1970, 62, 315-325.
24. Lougheed, W. D., Woulfe-Flanagan, H., Clement, J. R. and Albisser, A.M., Insulin aggregation in artificial delivery systems. Diabetologia, 1980, 19, 1-9.
25. Grau, U., Chemical stability of insulin in a delivery system environment. Diabetologia, 1985, 28, 458-463.