Regional and subcellular distribution of a neutral and basic amino acid transporter in forebrain neurons containing nitric oxide synthase

Journal of Comparative Neurology

Volumn 404, Issue 4, 1999, Pages 459-472

  Pickel, Virginia M ^a   Pohorille, A ^a   Chan, J ^a   Tate, S S ^a   Nirenberg, M J ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Electron microscopic immunocytochemistry; Hypothalamus; Limbic; Nucleus accumbens; rBAT

Indexed keywords

ARGININE; CARRIER PROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME LOCALIZATION; FOREBRAIN; IMMUNOGOLD STAINING; MALE; MICROSCOPY; NEUROTRANSMITTER RELEASE; NONHUMAN; ORGAN DISTRIBUTION; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT;

AMINO ACID TRANSPORT SYSTEMS, BASIC; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; AMINO ACIDS; ANIMALS; AXONS; BRAIN MAPPING; CARRIER PROTEINS; CEREBRAL CORTEX; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; MALE; NEOSTRIATUM; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; SILVER STAINING; SUBCELLULAR FRACTIONS; TERMINOLOGY; TISSUE FIXATION;

EID: 0033593932     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19990222)404:4<459::AID-CNE4>3.0.CO;2-9     Document Type: Article

References (56)

1. Alonso G. 1988. Effects of colchicine on the intraneuronal transport of secretory material prior to the axon: a morphofunctional study in hypothalamic neurosecretory neurons of the rat. Brain Res 453:191-203.
2. Bertran J, Werner A, Moore ML, Stange G, Markovich D, Biber J, Testar X, Zorzano A, Palacin M, Murer H. 1992. Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids. Proc Natl Acad Sci USA 89:5601-5605.
3. Bertran J, Werner A, Chillaron J, Nunes V, Biber J, Testar X, Zorzano A, Estivilli X, Murer H, Palacin MP. 1993. Expression cloning of a human renal cDNA that induces high affinity transport of L-cystine shared with dibasic amino acids in Xenopus oocytes. J Biol Chem 268:14842-14849.
4. Busch AE, Herzer T, Waldegger S, Schmidt F, Palacin M, Biber J, Markovich D, Murer H, Lang F. 1994. Opposite directed currents induced by the transport of dibasic and neutral amino acids in Xenopus oocytes expressing the protein rBAT. J Biol Chem 269:25581-25586.
5. Cameron P, Mundigl O, De Camilli P. 1993. Traffic of synaptic vesicle proteins in polarized and nonpolarized cells. J Cell Sci 17(Suppl):93-100.
6. Carter LL, Redelmeier TE, Woollenweber LA, Schmid SL. 1993. Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis. J Cell Biol 120:37-45.
7. Chan J, Aoki C, Pickel VM. 1990. Optimization of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding. J Neurosci Methods 33:113-127.
8. Coady MJ, Jalal F, Chen X, Lemay G, Berteloot A, Lapointe J-Y. 1994. Electrogenic amino acid exchange via the rBAT transporter. FEBS Lett 356:174-178.
9. Cortes R, Ceccatelli S, Schalling M, Hökfelt T. 1990. Differential effects of intracerebroventricular colchicine administration on the expression of mRNAs for neuropeptides and neurotransmitter enzymes, with special emphasis on galanin: an in situ hybridization study. Synapse 6:369-391.
10. DiFiglia M, Pasik T, Pasik P. 1980. Ultrastructure of Golgi-impregnated and gold-toned spiny and aspiny neurons in the monkey neostriatum. J Neurocytol 9:471-492.
11. Durante W, Liao L, Iftikhar I, O'Brien WE, Schafer AI. 1996. Differential regulation of L-arginine transport and nitric oxide production by vascular smooth muscle and endothelium. Circ Res 78:1075-1082.
12. Farb C, Aoki C, Milner T, Kaneko T, LeDoux J. 1992. Glutamate immunoreactive terminals in the lateral amygdaloid nucleus: a possible substrate for emotional memory. Brain Res 593:145-158.
13. Fernstrom MH, Fernstrom JD. 1995. Effect of chronic protein ingestion on rat central nervous system tyrosine levels and in vivo tyrosine hydroxylation rate. Brain Res 672:97-103.
14. Gracy KN, Svingos AL, Pickel VM. 1997. Dual ultrastructural localization of μ-opioid receptors and NMDA-type glutamate receptors in the shell of the rat nucleus accumbens. J Neurosci 17:4839-4848.
15. Hauri HP, Matter L. 1991. Protein traffic in intestinal epithelial cells. Semin Cell Biol 2:355-364.
16. Hediger MA. 1994. Structure, function and evolution of solute transporters in prokaryotes and eukaryotes. J Exp Biol 196:15-49.
17. Hendry SH, Jones EG, Emson PC. 1984. Morphology, distribution, and synaptic relations of somatostatin-and neuropeptide Y-immunoreactive neurons in rat and monkey neocortex. J Neurosci 4:2497-2517.
18. Hisano S, Haga H, Miyamoto KI, Takeda E, Fukui Y. 1996. The basic amino acid transporter (rBAT)-like immunoreactivity in paraventricular and supraoptic magnocellular neurons of the rat hypothalamus. Brain Res 710:299-302.
19. Horsford J, Saadi I, Raelson J, Goodyear PR, Rosen R. 1996. Molecular genetics of cystinuria in French Canadians: identification of four novel mutations in type I patients. Kidney. Int 49:1401-1406.
20. Iliakis B, Anderson NL, Irish PS, Henry MA, Westrum LE. 1996. Electron microscopy of immunoreactivity patterns for glutamate and gamma-aminobutyric acid in synaptic glomeruli of the feline spinal trigeminal nucleus (subnucleus caudalis). J Comp Neurol 366:465-477.
21. Kapatos G, Zigmond MJ. 1979. Regulation of dopamine synthesis in striatal synaptosomes during depolarization. Brain Res 170:299-312.
22. Kharazia VN, Schmidt HHHW, Weinberg RJ. 1994. Type I nitric oxide synthase fully accounts for NADPH-diaphorase in rat striatum, but not cortex. Neuroscience 62:983-987.
23. 2-adrenoceptors modulating hippocampal norepinephrine release in rat. Brain Res 674:238-244.
24. Koenig JA, Edwardson JM. 1994. Kinetic analysis of the trafficking of muscarinic acetylcholine receptors between the plasma membrane and intracellular compartments. J Biol Chem 269:17174-17182.
25. Lee W-S, Wells RG, Sabbag RV, Mohandas TK, Hediger MA. 1993. Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport. J Clin Invest 91:1959-1963.
26. Leranth C, Pickel VM. 1989. Electron microscopic pre-embedding double immunostaining methods. In: Heimer L, Zaborszky L, editors. Neuroanatomical tract-tracing methods 2: recent progress. New York: Plenum Publishing Company, p 129-172.
27. McGivan JD, Pastor-Anglada JD. 1994. Regulatory and molecular aspects of mammalian amino acid transport. Biochem J 299:321-334.
28. Miyamoto K, Katai K, Tatsumi S, Sone K, Segawa H, Yamamoto H, Taketani Y, Takada K, Morita K, Kanayama H, Kagawa S, Takeda E. 1995. Mutations of the basic amino acid transporter gene associated with cystinuria. Biochem J 310:951-955.
29. Morris SA, Schmid SL. 1995. Synaptic vesicle recycling: the Ferrari of endocytosis. Curr Biol 5:113-115.
30. Mosckovitz R, Yan N, Heimer E, Felix A, Tate SS, Udenfriend S. 1993. Characterization of the rat neutral and basic amino acid transporter utilizing anti-peptide antibodies. Proc Natl Acad Sci USA 90:4022-4026.
31. Mosckovitz R, Udenfriend S, Felix A, Heimer E, Tate SS. 1994. Membrane topology of the rat kidney neutral and basic amino acid transporter. FASEB J 8:1069-1074.
32. Mundigl O, De Camilli P. 1994. Formation of synaptic vesicles. Curr Opin Cell Biol 6:561-567.
33. Nirenberg MJ, Tate SS, Mosckovitz R, Udenfriend S, Pickel VM. 1995. Immunocytochemical localization of the renal neutral and basic amino acid transporter in rat adrenal gland, brainstem, and spinal cord. J Comp Neurol 356:505-522.
34. Nirenberg MJ, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. 1996. The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. J Neurosci 16:436-447.
35. Nirenberg MJ, Chan J, Pohorille A, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. 1997. The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens. J Neurosci 17:6899-6907.
36. Otake K, Reis DJ, Regunathan S, Wang H, Milner TA, Ruggiero DA. 1998. Regional localization of agmatine in rat brain: an immunocytochemical study. Brain Res 787:1-14.
37. Peters A, Palay SL, Webster HD. 1991. The fine structure of the nervous system. New York: Oxford University Press.
38. Pickel VM, Nirenberg MJ, Chan J, Mosckovitz R, Udenfriend S, Tate SS. 1993. Ultrastructural localization of a neutral and basic amino acid transporter in rat kidney and intestine. Proc Natl Acad Sci USA 90:7779-7783.
39. Pisoni RL, Thoene JG. 1991. The transport systems of mammalian lysosomes. Biochim Biophys Acta 1071:351-373.
40. Qian Y, Melikian HE, Rye DB, Levey AI, Blakely RD. 1995. Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies. J Neurosci 15:1261-1274.
41. Reis DJ, Regunathan S. 1998. Agmatine: an endogenous ligand at imidazoline receptors may be a novel neurotransmitter in brain. J Auton Nerv Syst (in press).
42. Roberts VJ, Gorenstein C. 1990. The effect of antimitotic agents on the intraneuronal distribution of lysosomes. Brain Res 521:62-72.
43. Rodrigo J, Riveros-Moreno V, Bentura ML, Uttenthal LO, Higgs AE, Fernandez AP, Polak JM, Moncada S, Martinez-Murillo R. 1997. Subcellular localization of nitric oxide synthase in the cerebral ventricular system, subfornical organ, area postrema, and blood vessels of the rat brain. J Comp Neurol 378:522-534.
44. Sachenko PE, Swanson LW. 1982. The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat. Brain Res Rev 4:275-325.
45. Schafer T, Karli UO, Schweizer FE, Burger MM. 1987. Docking of chromaffin granules - a necessary step in exocytosis? Biosci Rep 7:269-279.
46. Schmidt K, List BM, Klatt P, Mayer B. 1995. Characterization of neuronal amino acid transporters: uptake of nitric oxide synthase inhibitors and implication for their biological effects. J Neurochem 64:1469-1475.
47. Seamans JK, Floresco SB, Phillips AG. 1995. Functional differences between the prelimbic and anterior cingulate regions of the rat prefrontal cortex. Behav Neurosci 109:1063-1073.
48. Segal S, Thier SO. 1995. Cystinuria. In: Scriver CR, Beaudet AL, Sly WS, Valle D, editors. The metabolic and molecular bases of inherited disease. New York: McGraw-Hill, p 3581-3601.
49. Segovia G, Mora F. 1998. Role of nitric oxide in modulating the release of dopamine, glutamate, and GABA in striatum of the freely moving rat. Brain Res Bull 45:275-279.
50. Stuehr, DJ. 1997. Structure-function aspects in the nitric oxide synthases. Annu Rev Pharmacol Toxicol 37:339-359.
51. Swanson LW. 1992. Brain maps, structure of the rat brain. Amsterdam: Elsevier.
52. Tam SY, Roth RH. 1997. Mesoprefrontal dopaminergic neurons: can tyrosine availability influence their functions? Biochem Pharmacol 53:441-453.
53. Tate SS, Yan N, Udenfriend S. 1992. Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney. Proc Natl Acad Sci USA 89:1-5.
54. 3H]-noradrenaline from rat spinal cord. Brain Res Bull 42:129-132.
55. Wang Y, Tate SS. 1995. Oligomeric structure of a renal cystine transporter: Implications in cystinuria. FEES Lett 368:389-392.
56. Wells RG, Hediger MA. 1992. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidase. Proc Natl Acad Sci USA 89:5596-5600.