Attenuated amplitude of circadian and sleep-dependent modulation of electroencephalographic sleep spindle characteristics in elderly human subjects

Neuroscience Letters

Volumn 260, Issue 1, 1999, Pages 29-32

  Wei, Henry G ^a,b   Riel, Eymard ^a   Czeisler, Charles A ^a,c   Dijk, Derk Jan ^a  

^a Circadian   (United States)

^b HARVARD COLLEGE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aging; Body temperature; Circadian; Non REM sleep; Sleep; Spindles

Indexed keywords

ADULT; AGED; AGING; AMPLITUDE MODULATION; ARTICLE; BODY TEMPERATURE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; FEMALE; FREQUENCY ANALYSIS; HUMAN; MALE; NONREM SLEEP; OSCILLATION; PRIORITY JOURNAL; SLEEP SPINDLE;

NON-PROGRAMMATIC;

ADULT; AGE FACTORS; AGED; BODY TEMPERATURE; CIRCADIAN RHYTHM; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; MALE; SLEEP;

EID: 0033593380     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00851-9     Document Type: Article

References (21)

1. Aeschbach D., Dijk D.-J., Borbély A.A. Dynamics of EEG spindle frequency activity during extended sleep in humans: relationship to slow-wave activity and time of day. Brain Res. 748:1997;131-136.
2. Bliwise D.L. Review: sleep in normal aging and dementia. Sleep. 16:1993;40-81.
3. Brown E.N., Czeisler C.A. The statistical analysis of circadian phase and amplitude in constant-routine core-temperature data. J. Biol. Rhythms. 7:1992;177-202.
4. Czeisler C.A., Duffy F., Shanahan T.L., Brown E.N., Mitchell J., Dijk D.-J., Ronda J.M., Allan J.S., Emens J.S., Rimrner D.W., Kronauer R.E. Reassessment of the intrinsic period (τ) of the human circadian pacemaker in young and older subjects. Sleep Res. 24A:1995;505.
5. Czeisler C.A., Dumont M., Duffy J.F., Steinberg J.D., Richardson G.S., Brown E.N., Sanchez R., Rios C.D., Ronda J.M. Association of sleep-wake habits in older people with changes in output of circadian pacemaker. Lancet. 340:1992;933-936.
6. Destexhe A., Contreras D., Sejnowski T.J., Steriade M. A model of spindle rhythmicity in the isolated thalamic reticular nucleus. J. Neurophysiol. 72:1994;803-818.
7. Dijk D.-J., Czeisler C.A. Paradoxical timing of the circadian rhythm of sleep propensity serves to consolidate sleep and wakefulness in humans. Neurosci. Lett. 16:1994;63-68.
8. Dijk D.-J., Czeisler C.A. Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves and sleep spindle activity in humans. J. Neurosci. 15:1995;3526-3538.
9. Dijk D.-J., Duffy J.F., Riel E., Czeisler C.A. Altered interaction of circadian and homeostatic aspects of sleep propensity results in awakening at an earlier circadian phase in older people. Sleep Res. 26:1997;710.
10. Dijk D.-J., Hayes B., Czeisler C.A. Dynamics of electroencephalographic sleep spindles and slow wave activity in men: effect of sleep deprivation. Brain Res. 626:1993;190-199.
11. Dijk, D.-J., Shanahan, T.L., Duffy, J.F., Ronda, J.M. and Czeisler, C.A., Variation of electroencephalographic activity during nonREM and REM sleep with phase of circadian melatonin rhythm in humans, J. Physiol. (Lond.), 505.3 (1997) 851-858.
12. Duffy J.F., Dijk D.-J., Klerman E.B., Czeisler C.A. Later endogenous circadian temperature nadir relative to an earlier wake time in older people. Am. J. Physiol. 275:1998;R1478-R1487.
13. Guazelli M., Feinberg I., Aminoff M., Fein G., Floyd T.C., Magginin C. Sleep spindles in normal elderly: comparison with young adult patterns and relation to nocturnal awakening, cognitive function and brain atrophy. Electroenceph. clin. Neurophysiol. 63:1986;526-539.
14. Landolt H.P., Dijk D.-J., Achermann P., Borbely A.A. Effect of age on the sleep EEG: slow-wave activity and spindle frequency activity in young and middle-aged men. Brain Res. 738:1996;205-212.
15. Martens, W.L.J. and Kap, J.I., Method and System for Analysis of Long Term Physiological Polygraphic Recordings, United States Patent No. 5,046,930, 1991.
16. McCormick D.A., Bal T. Sleep and arousal: thalamocortical mechanisms. Annu. Rev. Neurosci. 20:1997;185-215.
17. Myers B.L., Badia P. Changes in circadian rhythms and sleep quality with aging: mechanisms and interventions. Neurosci. Biobehav. Rev. 19:1995;553-571.
18. Principe J.C., Smith J.R. Sleep spindle characteristics as a function of age. Sleep. 5:1982;73-84.
19. Shanahan T.L., Czeisler C.A. Light exposure induces equivalent phase shifts of the endogenous circadian rhythms of circulating plasma melatonin and core body temperature in men. J. Clin. Endocrinol. Metab. 73:1991;227-235.
20. Steriade M., McCormick D.A., Sejnowski T.J. Thalamocortical oscillations in the sleeping and aroused brain. Science. 262:1993;679-685.
21. Werth E., Achermann P., Dijk D.-J., Borbély A.A. Spindle frequency activity in the sleep EEG: individual differences and topographic distribution. Electroenceph. clin. Neurophysiol. 103:1997;535-542.