19/20 kDa low molecular weight serum protein pattern: A novel potential biochemical prognostic marker for different types of dementia

Neuroscience Letters

Volumn 260, Issue 1, 1999, Pages 61-64

  Lombardi, Valter R M ^a   Cacabelos, Ramón ^a  

^a Centro de Investigacion Biomedica EuroEspes   (Spain)

Author keywords

Alzheimer's disease; Mixed dementia; Vascular dementia

Indexed keywords

BIOCHEMICAL MARKER; CELL PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DISEASE COURSE; GENOTYPE; HUMAN; MOLECULAR WEIGHT; MULTIINFARCT DEMENTIA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BIOLOGICAL MARKERS; BLOOD PROTEINS; DEMENTIA; DEMENTIA, VASCULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MIDDLE AGED; PROGNOSIS; SODIUM DODECYL SULFATE;

EID: 0033593359     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00960-4     Document Type: Article

References (18)

1. Alvarez X.A., Franco A., Fernández-Novoa L., Cacabelos R. Blood levels of histamine, IL-1β, and TNF-α in patients with mild to moderate Alzheimer disease. Mol. Chem. Neuropathol. 29:1996;237-252.
2. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th edn., American Psychiatric Association, Washington, DC, 1994.
3. Beyer K., Lao J.I., Cacabelos R. Molecular genotyping in Alzheimer's disease. Ann. Psych. 6:1996;173-187.
4. Blacker D., Wilcox M.A., Laird N.M., Rodes L., Horvath S.M., Go R.C.P., Perry R., Watson B. Jr., Bassett S.S., McInnis M.G., Albert M.S., Hyman B.T., Tanzi R.E. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat. Genet. 19:1998;357-360.
5. Cacabelos R. Diagnosis of Alzheimer's disease: defining genetic profiles (genotype vs. phenotype). Acta Neurol. Scand. Suppl. 165:1996;72-84.
6. Cacabelos R., Rodríguez B., Carrera C., Beyer K., Lao J.I., Sellers M.A. APOE-related dementia symptoms: frequency and progression. Ann. Psych. 6:1996;189-205.
7. Connor J.R., Menzies S.L. St. Martin, S.M. and Mufson, E.J., A histochemical study of iron, transferrin and ferritin in Alzheimer's disease brain. J. Neurosci. Res. 31:1992;75-83.
8. Davidsson P., Jahn R., Bergquist J., Ekman R., Blennow K. Synaptotagmin, a synaptic vescicle protein, is present in human cerebrospinal fluid: a new biochemical marker for synaptic pathology in Alzheimer disease? Mol. Chem. Neuropathol. 27:1996;195-210.
9. Farrer L.A., Stice L. Suceptibility genes for familial Alzheimer's disease on chromosome 19 and 21: a reality check. Genet. Epidemiol. 9:1992;123-127.
10. Folstein M.F., Folstein S.E., Mc Hugh P.R. 'Mini Mental-State'. A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12:1975;189-198.
11. Guo, C., Marynen, P. and Cassinen, J.J., A rapid semiautomated method for apolipoprotein E genotyping. PCR Methods and Applications, Vol. 2, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993, pp. 348-350.
12. Kennard M.L., Feldman H., Yamada T., Jefferies W.A. Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease. Nat. Med. 2:1996;1230-1235.
13. Kovacs D.M., Fausett H.J., Page K.J., Kim T.W., Moir R.D., Merriam D.E., Hollister R.D., Hallmark O.G., Mancini R., Felsenstein K.M., Hyman B.T., Tanzi R.E., Wasco W. Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nat. Med. 2:1996;224-229.
14. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of NINCDS-ADRDA work group. Neurology. 34:1984;939-944.
15. Reiseberg, B., Ferris, S.H., de León, M.J. and Crook, T., Age-associated Cognitive Decline and Alzheimer's Disease: Implications for Assessment and Treatment, Threshold in Aging, Academic Press, London, 1985, pp. 254-292.
16. Schellenberg G.D., Periack-Vance M.A., Wijsman E.M., Morre D.K., Gaskell P.C., Yamaoka L.A., Bebout J.L., Anderson L., Welsh K.A., Clark C.M., Martin G.M., Roses A.D., Bird T.D. Linkage analysis of familial Alzheimer's disease, using chromosome 21 markers. Am. J. Hum. Genet. 48:1991;563-583.
17. Tohgi H., Abe T., Kimura M., Saheki M., Takahashi S. Cerebrospinal fluid acetylcholine and choline in vascular dementia of Biswanger and multiple small infarct types as compared with Alzheimer-type dementia. J. Neural. Transm. 103:1996;1211-1220.
18. Vázquez J., Fernández-Shaw C., Marina A., Haas C., Cacabelos R., Valdivieso F. Antibodies to human brain spectrin in Alzheimer's disease. J. Neuroimmunol. 68:1996;39-44.