Crystal structure of the H256A mutant of rat testis fructose-6- phosphate,2-kinase/fructose-2,6-bisphosphatase: Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities

Journal of Biological Chemistry

Volumn 274, Issue 4, 1999, Pages 2176-2184

  Yuen, Mi H ^a   Mizuguchi, Hiroyuki ^a,b   Lee, Yong Hwan ^a   Cook, Paul F ^c   Uyeda, Kosaku ^a,b   Hasemann, Charles A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATASE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; RAT; TESTIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; FRUCTOSEDIPHOSPHATES; MALE; MODELS, MOLECULAR; PHOSPHOFRUCTOKINASE-2; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN CONFORMATION; RATS; TESTIS;

EID: 0033593452     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.4.2176     Document Type: Article

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