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3. (a) For the original synthesis of DDATHF, see Taylor, E. C.; Harrington, P. J.; Fletcher, S. R.; Beardsley, G. P.; Moran, R. G. J. Med. Chem. 1985, 28, 914.
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(d) Baldwin, S. W.; Tse, A.; Gossett, L. S.; Taylor, E. C., Rosowsky, A.; Shih, C.; Rinzel, S. M.; Grindey, G. B.; Barredo, J.; Jannatapour, M.; Moran, R. G. J. Med. Chem. 1992, 35, 4450.
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(e) For reviews, see Taylor, E. C. J. Heterocycl, Chem. 1990, 27, 1; Taylor, E. C. Chemistry and Biology of Pteridines and Folates, Ayling, J. E.; Nair, M. G.; Baugh, C. M., eds, Plenum Press, 1993, pp. 387.
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