Genetic variation in susceptibility to endocrine disruption by estrogen in mice

Science

Volumn 285, Issue 5431, 1999, Pages 1259-1261

  Spearow, Jimmy L ^c   Doemeny, Paul ^a,c   Sera, Robyn ^c   Leffler, Rachael ^b,c   Barkley, Marylynn ^c  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GENENTECH INC   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; CELL MATURATION; CONTROLLED STUDY; FERTILITY; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HISTOLOGY; HORMONE ACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENTIATION; SPERMATID; STRAIN DIFFERENCE; TESTIS WEIGHT;

ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; LITTER SIZE; MALE; MICE; MICE, INBRED STRAINS; ORGAN SIZE; SPECIES SPECIFICITY; SPERMATIDS; SPERMATOGENESIS; TESTIS; TOXICITY TESTS; VARIATION (GENETICS);

EID: 0033588144     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5431.1259     Document Type: Article

References (36)

1. S. Jobling, T. Reynolds, R. White, M. G. Parker, J. P. Sumpter, Environ. Health Perspect. 103, 582 (1995); F. S. vom Saal et al., Toxicol. Ind. Health 14, 239 (1998).
2. S. Jobling, T. Reynolds, R. White, M. G. Parker, J. P. Sumpter, Environ. Health Perspect. 103, 582 (1995); F. S. vom Saal et al., Toxicol. Ind. Health 14, 239 (1998).
3. C. Sonnenschein and A. M. Soto, J. Steroid Biochem. Mol. Biol. 65, 143 (1998).
4. D. L. Davis, N. T. Telang, M. P. Osborne, H. L. Bradlow, Environ. Health Perspect. 105 (suppl. 3), 571 (1997); L. J. Paulozzi, J. D. Erickson, R. J. Jackson, Pediatrics 100, 831 (1997); A. Shibata, J. Ma, A. S. Whittemore, J. Natl. Cancer Inst. 90, 1230 (1998); S. H. Swan and E. P. Elkin, Bioessays 21, 614 (1999).
5. D. L. Davis, N. T. Telang, M. P. Osborne, H. L. Bradlow, Environ. Health Perspect. 105 (suppl. 3), 571 (1997); L. J. Paulozzi, J. D. Erickson, R. J. Jackson, Pediatrics 100, 831 (1997); A. Shibata, J. Ma, A. S. Whittemore, J. Natl. Cancer Inst. 90, 1230 (1998); S. H. Swan and E. P. Elkin, Bioessays 21, 614 (1999).
6. D. L. Davis, N. T. Telang, M. P. Osborne, H. L. Bradlow, Environ. Health Perspect. 105 (suppl. 3), 571 (1997); L. J. Paulozzi, J. D. Erickson, R. J. Jackson, Pediatrics 100, 831 (1997); A. Shibata, J. Ma, A. S. Whittemore, J. Natl. Cancer Inst. 90, 1230 (1998); S. H. Swan and E. P. Elkin, Bioessays 21, 614 (1999).
7. D. L. Davis, N. T. Telang, M. P. Osborne, H. L. Bradlow, Environ. Health Perspect. 105 (suppl. 3), 571 (1997); L. J. Paulozzi, J. D. Erickson, R. J. Jackson, Pediatrics 100, 831 (1997); A. Shibata, J. Ma, A. S. Whittemore, J. Natl. Cancer Inst. 90, 1230 (1998); S. H. Swan and E. P. Elkin, Bioessays 21, 614 (1999).
8. A. M. Soto and C. Sonnenschein, Comments Toxicol. 5, 329 (1996); J. Blanco-Rodriguez and C. Martinez-Garcia, J. Reprod. Fertil. 110, 61 (1997).
9. A. M. Soto and C. Sonnenschein, Comments Toxicol. 5, 329 (1996); J. Blanco-Rodriguez and C. Martinez-Garcia, J. Reprod. Fertil. 110, 61 (1997).
10. G. E. Bradford, Genetics 58, 283 (1968); R. B. Land and D. S. Falconer, Genet. Res. 13, 25 (1969); V. D. Toelle, B. H. Johnson, O. W. Robison, J. Anim. Sci. 59, 967 (1984).
11. G. E. Bradford, Genetics 58, 283 (1968); R. B. Land and D. S. Falconer, Genet. Res. 13, 25 (1969); V. D. Toelle, B. H. Johnson, O. W. Robison, J. Anim. Sci. 59, 967 (1984).
12. G. E. Bradford, Genetics 58, 283 (1968); R. B. Land and D. S. Falconer, Genet. Res. 13, 25 (1969); V. D. Toelle, B. H. Johnson, O. W. Robison, J. Anim. Sci. 59, 967 (1984).
13. G. E. Bradford, J. L. Spearow, J. P. Hanrahan, in Reproduction in Domestic Animals, P. T. Cupps, Ed. (Academic Press, New York, 1991), pp. 605-636.
14. J. L. Spearow, in Polycystic Ovary Syndrome, R. J. Chang, Ed. (Springer-Verlag, New York, 1996), pp. 1-20.
15. _, J. Reprod. Fertil. 82, 787 (1988); J. L. Spearow and M. Barkley, Biol. Reprod. 61, 851 (1999).
16. _, J. Reprod. Fertil. 82, 787 (1988); J. L. Spearow and M. Barkley, Biol. Reprod. 61, 851 (1999).
17. R. B. Land, Nature 241, 208 (1973).
18. J. L. Spearow, J. Turgai, F. C. Mao, P. Smith, B. Trost, J. Anim. Sci. 65 (suppl. 1), 399 (1987).
19. S. Erickson et al., Biol. Reprod. 52 (suppl. 1), 70 (1995).
20. G. E. Bradford, Genetics 61, 905 (1969).
21. J. L. Spearow and G. E. Bradford, J. Reprod. Fertil. 69, 529 (1983).
22. 2 implants, respectively (23).
23. H. Inano, K. Suzuki, M. Onoda, K. Wakabayashi, Carcinogenesis 17, 355 (1996).
24. 2 showed even more extreme testicular atrophy (18).
25. J. M. Whitsett, P. F. Noden, J. Cherry, A. D. Lawton, J. Reprod. Fertil. 72, 277 (1984).
26. J. L. Spearow et al., data not shown.
27. - and E were not more resistant to endocrine disruption than inbred sublines. Furthermore, all CD-1 males were highly resistant to endocrine disruption.
28. M. Silberberg and R. Silberberg, Proc. Soc. Exp. Biol. Med. 78, 161 (1951); P. J. Claringbold and J. D. Biggers, J. Endocrinol. 12, 9 (1955).
29. M. Silberberg and R. Silberberg, Proc. Soc. Exp. Biol. Med. 78, 161 (1951); P. J. Claringbold and J. D. Biggers, J. Endocrinol. 12, 9 (1955).
30. J. W. Pollard, Endocrinology 140, 553 (1999); R. J. Roper et al., ibid., p. 556; B. W. Kirkpatrick, A. Mengelt, N. Schulman, I. C. A. Martin, Mamm. Genome 9, 97 (1998); J. L. Spearow et al., Biol. Reprod. 61, 857 (1999).
31. J. W. Pollard, Endocrinology 140, 553 (1999); R. J. Roper et al., ibid., p. 556; B. W. Kirkpatrick, A. Mengelt, N. Schulman, I. C. A. Martin, Mamm. Genome 9, 97 (1998); J. L. Spearow et al., Biol. Reprod. 61, 857 (1999).
32. J. W. Pollard, Endocrinology 140, 553 (1999); R. J. Roper et al., ibid., p. 556; B. W. Kirkpatrick, A. Mengelt, N. Schulman, I. C. A. Martin, Mamm. Genome 9, 97 (1998); J. L. Spearow et al., Biol. Reprod. 61, 857 (1999).
33. J. W. Pollard, Endocrinology 140, 553 (1999); R. J. Roper et al., ibid., p. 556; B. W. Kirkpatrick, A. Mengelt, N. Schulman, I. C. A. Martin, Mamm. Genome 9, 97 (1998); J. L. Spearow et al., Biol. Reprod. 61, 857 (1999).
34. WHO-Contraceptive-Task-Force, Lancet 336, 955 (1990); H. Behre et al., J. Clin. Endocrinol. Metab. 80, 2394 (1995).
35. WHO-Contraceptive-Task-Force, Lancet 336, 955 (1990); H. Behre et al., J. Clin. Endocrinol. Metab. 80, 2394 (1995).
36. C. Munro and G. Stabenfeldt, J. Endocrinol. 101, 41 (1984).