Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 15, 1999, Pages 8378-8383

  Dhe Paganon, Sirano ^a   Ottinger, Elizabeth A ^a,c   Nolte, Robert T ^b,d   Eck, Michael J ^a   Shoelson, Steven E ^a,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c KENYON COLLEGE   (United States)

^d GLAXOSMITHKLINE   (United States)

^e JOSLIN DIABETES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN; INSULIN RECEPTOR SUBSTRATE 1; LIGAND; PHOSPHOTYROSINE; PLECKSTRIN; POLYPHOSPHOINOSITIDE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOPROTEINS; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 0033587724     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.15.8378     Document Type: Article

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