A biochemical and biophysical characterization of recombinant mutants of fetal hemoglobin and their interaction with sickle cell hemoglobin

Biochemistry

Volumn 38, Issue 29, 1999, Pages 9549-9555

  Larson, Sandra C ^a   Fisher, Gregory W ^a   Ho, Nancy T ^a   Shen, Tong Jian ^a   Ho, Chien ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DIMER; HEMOGLOBIN A; HEMOGLOBIN F; HEMOGLOBIN S; MUTANT PROTEIN; RECOMBINANT PROTEIN; TETRAMER; THREONINE; TRYPTOPHAN; TYROSINE;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DISSOCIATION; FETUS; GENE THERAPY; HEMOGLOBIN ANALYSIS; HUMAN; HUMAN CELL; ISOELECTRIC FOCUSING; OXYGEN AFFINITY; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RECOMBINANT DNA TECHNOLOGY; SICKLE CELL ANEMIA; UMBILICAL CORD BLOOD;

ADULT; ALKALIES; CHEMISTRY, PHYSICAL; DENSITOMETRY; FETAL BLOOD; FETAL HEMOGLOBIN; FREEZING; HEMOGLOBIN A; HEMOGLOBIN, SICKLE; HUMANS; ISOELECTRIC FOCUSING; OXYGEN; PROTEIN DENATURATION; RECOMBINANT PROTEINS;

EID: 0033587556     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990740o     Document Type: Article

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