Kinetics of retrovirus production and decay

Biotechnology and Bioengineering

Volumn 63, Issue 6, 1999, Pages 654-662

  Le Doux, Joseph M ^a   Davis, Howard E ^a   Morgan, Jeffrey R ^a   Yarmush, Martin L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Gene therapy; Recombinant retroviruses; Transduction efficiency; Virus decay; Virus production; Virus titer

Indexed keywords

BATCH CELL CULTURE; BIOASSAY; DECAY (ORGANIC); GENE TRANSFER; GROWTH KINETICS; MATHEMATICAL MODELS; TEMPERATURE;

GENE THERAPY; RECOMBINANT RETROVIRUS; RETROVIRUS PRODUCTION; TRANSDUCTION EFFICIENCY; VIRUS DECAY; VIRUS TITER;

VIRUSES;

CAPSID PROTEIN;

ANIMAL CELL; ARTICLE; GENE THERAPY; GENETIC TRANSDUCTION; KINETICS; MATHEMATICAL MODEL; NONHUMAN; RETROVIRUS; TEMPERATURE; VIRUS RECOMBINANT; VIRUS TITRATION;

3T3 CELLS; ANIMALS; BETA-GALACTOSIDASE; BIOTECHNOLOGY; CAPSID; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC ENGINEERING; MICE; MODELS, BIOLOGICAL; RECOMBINANT PROTEINS; RETROVIRIDAE; TEMPERATURE; TRANSDUCTION, GENETIC; VIRUS REPLICATION;

ACRONICTA LEPORINA; ANIMALIA; ESCHERICHIA COLI; MIRIDAE; UNIDENTIFIED RETROVIRUS;

EID: 0033587377     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19990620)63:6<654::AID-BIT3>3.0.CO;2-1     Document Type: Article

References (26)

1. Bahnson AB, Dunigan JT, Baysal BE, Mohney T, Atchison RW, Nimgaonkar MT, Ball ED, Barranger JA. 1995. Centrifugal enhancement of retroviral mediated gene transfer. J Virol Methods 54:131-143.
2. Bunnell BA, Muul LM, Donahue RE, Blaese RM, Morgan RA. 1995. High-efficiency retroviral-mediated gene transfer into human and non-human primate peripheral blood lymphocytes. Proc Natl Acad Sci USA 92:7739-7743.
3. Dhawan J, Pan LC, Pavlath GK, Travis MA, Lanctot AM, Blau HM. 1991. Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science 254:1509-1512.
4. Dougherty RM. 1961. Heat inactivation of Rous' sarcoma virus. Virology 14:371-372.
5. Forestell SP, Bohnlein E, Rigg RJ. 1995. Retroviral end-point titer is not predictive of gene transfer efficiency: Implications for vector production. Gene Ther 2:723-730.
6. Ginoza W. 1968. Inactivation of viruses by ionizing radiation and heat. In: Maramorosch K, Koprowski H, editors. Methods in virology. New York: Academic Press, p 139-209.
7. Harlow E, Lane D. 1988. Antibodies: A laboratory manual. Plainview, NY: Cold Spring Harbor Laboratory Press.
8. Kahn ML, Lee SW, Dichek DA. 1992. Optimization of retroviral vector-mediated gene transfer into endothelial cells in vitro. Circulation Res 71:1508-1517.
9. Kaptein L, Greijer A, Valerio D, van Beusechem V. 1997. Optimized conditions for the production of recombinant amphotropic retroviral vector preparations. Gene Ther 4:172-176.
10. Kobinger GP, Mouland AJ, Lalonde JP, Forget J, Cohen EA. 1997. Enhancement of retroviral production from packaging cell lines expressing the human immunodeficiency type 1 VPU gene. Gene Ther 4: 868-874.
11. Kotani H, Newton PB, Zhang S, Chiang YL, Otto E, Weaver L, Blaese RM, Anderson WF, McGarrity GJ. 1994. Improved methods of retroviral vector transduction and production for gene therapy. Human Gene Ther 5:19-28.
12. Le Doux JM, Morgan JR, Snow RG, Yarmush ML. 1996. Proteoglycans secreted by packaging cell lines inhibit retrovirus infection. J Virol 70:6468-6473.
13. LeDoux JM, Morgan JR, Yarmush ML. 1998. Removal of proteoglycans increases the efficiency of retroviral gene transfer. Biotechnol Bioeng Prog 58:23-34.
14. Lee SG, Kim S, Robbins PD, Kim BG. 1996. Optimization of environmental factors for the production and handling of recombinant retrovirus. Appl Microbiol Biotechnol 45:477-483.
15. Legrain P, Goud B, Buttin G. 1986. Increase of retroviral infection in vitro by the binding of antiretroviral antibodies. J Virol 60:1141-1144.
16. Lim K, Chae CB. 1989. A simple assay for DNA transfection by incubation of the cells in culture dishes with substrates for β-galactosidase. BioTechniques 7:576-579.
17. Miller AD. 1990. Progress towards human gene therapy. Blood 76: 271-278.
18. Morgan JR, Le Doux JM, Snow RG, Tompkins RG, Yarmush ML. 1995. Retrovirus infection: Effect of time and target cell number. J Virol 69:6994-7000.
19. Morgan JR, Lee J, Tompkins RG, Yarmush ML. 1994. Rapid quantitation of recombinant retroviruses. Biotechnol Prog 10:441-446.
20. Mulligan RC. 1993. The basic science of gene therapy. Science 260: 926-932.
21. Orkin SH, Motulsky AG. 1995. Report and recommendations of the panel to assess the NIH investment in research on gene therapy. Bethesda, MD: National Institutes of Health.
22. Price J, Turner D, Cepko C. 1987. Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer. Proc Natl Acad Sci USA 84:156-160.
23. Rigg RJ, Chen J, Dando JS, Forestell SP, Plavec I, Bohnlein E. 1996. A novel human amphotropic packaging cell line: High titer, complement resistance, and improved safety. Virology 218:290-295.
24. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: A laboratory manual. Plainview, NY: Cold Spring Harbor Laboratory Press.
25. Shen BQ, Clarke MF, Palsson BO. 1996. Kinetics of retroviral production from the amphotropic psi-CRIP murine producer cell line. Cytotechnology 22:185-195.
26. Xu L, Young H, Blanco M, Kessler S, Roberts A, Karlsson S. 1994. Poor transduction efficiency of human hematopoietic progenitor cells by a high-titer amphotropic retrovirus producer cell clone. J Virol 68: 7634-7636.