Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site

Oncogene

Volumn 18, Issue 20, 1999, Pages 3071-3075

  Van Der Geer, Peter ^a,b   Wiley, Sandra ^b   Pawson, Tony ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

IRS 1; Protein modules; PTB domain specificity; Shc

Indexed keywords

AMINO ACID; CYTOPLASM PROTEIN; DOCKING PROTEIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR RECEPTOR; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; BINDING SITE; CELL STRAIN COS1; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; COS CELLS; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PRECIPITIN TESTS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

ANIMALIA;

EID: 0033587097     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202879     Document Type: Article

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