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(f) We are grateful to Professor Doctor Albert Eschenmoser, ETH-Z, for providing us with experimental details, and spectral data, for several unpublished procedures.
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Transformations of this type are well precedented for vinyl/aryl halides and internal alkyne acids: Arcadi, A.; Burini, A.; Cacchi, S.; Delmastro, M.; Marinelli, F.; Pietrono, B. R. J. Org. Chem. 1992, 57, 976 and references cited therein.
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See, for example: Micklefield, J.; Mackman, R. L.; Aucken, C. J.; Beckmann, M.; Block, M. H.; Leeper, F. J.; Battersby, A. R. J. Chem. Soc. Chem. Commun 1993, 275 and references therein.
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26
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0344060608
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note
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Satisfactory analytical and spectral data were obtained for all new compounds reported.
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27
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0344060607
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note
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Financial support of this work by the National Institutes of Health, NIGMS Grant No. GM38913, and the National Science Foundation, Grant No. CHE-9424476, is gratefully acknowledged.
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