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(a) Acetylenic acid 17a: Aldrich Chemical Co., Milwaukee, WI.
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Acid cyclizations: (a) Chan, D. M. T.; Marder, T. B.; Milstein, D.; Taylor, N. J. J. Am. Chem. Soc. 1987, 109, 6385. (b) Marder, T. B.; Chan, D. M.-T.; Fultz, W. C.; Calabrese, J. C.; Milstein, D. J. Chem. Soc., Chem. Commun. 1987, 1885. (c) Arcadi, A.; Burini, A.; Cacchi, S.; Delmastro, M.; Marinelli, F.; Pietroni, B. R. J. Org. Chem. 1992, 57, 976 and references cited therein. (d) Reed, P. E.; Katzenellenbogen, J. A. J. Org. Chem. 1991, 56, 2624.
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We are grateful to Dr. Robert DeSimone for initially carrying out this reaciton
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(b) We are grateful to Dr. Robert DeSimone for initially carrying out this reaciton.
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80
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15844418140
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We are grateful to Dr. Wanjun Zheng for initially carrying out this reaction
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(c) We are grateful to Dr. Wanjun Zheng for initially carrying out this reaction.
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