Partition coefficients (free ligands and their iron(III) complexes) and lipophilic behavior of new abiotic chelators. Correlation to biological activity

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 20, 1999, Pages 3035-3040

  Thomas, F ^a   Baret, P ^a   Imbert, D ^a   Pierre, Jean Louis ^a   Serratrice, G ^a  

^a UNIVERSITÉ JOSEPH FOURIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATING AGENT; FERRIC ION; IRON COMPLEX; LIGAND; OCTANOL; WATER;

ARTICLE; CHELATION; CHEMICAL STRUCTURE; COMPLEX FORMATION; LIPOPHILICITY; PARTITION COEFFICIENT;

FERRIC COMPOUNDS; IRON CHELATING AGENTS; LIGANDS; LIPIDS; OCTANOLS; WATER;

EID: 0033581590     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00527-2     Document Type: Article

References (15)

1. Winkelman, G., Ed., CRC Handbook of Microbial Iron Chelates; CRC Press, Boca Raton, 1991.
2. Sigel, A. and Sigel, H., Eds., Iron Transport and Storage in Microorganisms, Plants and Animals; Metal Ions in Biological Systems, Vol. 35, M. Dekker : New-York, 1998.
3. Raymond, K.N.; Müller, G.; Matzanke, B.F. Top. Curr. Chem. 1984, 123, 49-102.
4. Hansch, C. Acc. Chem. Res. 1969, 2, 232-239.
5. Baret, P.; Béguin, C.; Boukhalfa, H.; Caris, C.; Laulhère, J-P.; Pierre J-L.; Serratrice, G. J. Am. Chem. Soc. 1995, 117, 9760-9761.
6. Caris, C.; Baret, P.; Béguin, C.; Serratrice, G.; Pierre, J-L.; Laulhère, J-P. Biochem. J. 1995, 312, 879- 885.
7. Rakba, N.; Henry, C.; Caris, C.; Morel, I.; Pasdeloup, N.; Baret, P.; Pierre, J-L.; Brissot, P.; Lescoat, G.; Crichton, R.R. Biochem. Pharmacol. 1998, 55, 1797-1806.
8. Serratrice, G.; Boukhalfa, H.; Béguin, C.; Baret, P.; Caris, C.; Pierre, J-L. Inorg. Chem. 1997, 36, 3898- 3910.
9. Thomas, F.; Béguin, C.; Pierre, J-L.; Serratrice, G. Inorg. Chim. Acta 1999, 291, 148-157.
10. Unpublished results
11. Baret, P.; Béguin, C.; Gellon, G.; Pierre, J-L.; Serratrice, G.; Thomas, F.; Laulhère, J.-P.; Saint-Aman, E. (submitted)
12. Edward, J.T.; Ponka, P.; Richardson, D.R. Biometals 1995, 8, 209-217.
13. Edward, J.T. Biometals 1998, 11, 203-205.
14. Rai, B.L.; Dekhordi, L.S.; Khodr, H.; Jin, Y.; Liu, Z.; Hider, R.C. J. Med. Chem. 1998, 41, 3347- 3359.
15. Bollinger, J.E.; Mague, J.; O'Connor; C.J.; Banks, W.A.; Roundhill, D.M. J. Chem. Soc. Dalton Trans. 1995, 1677-1688.