Synthesis and antitumor activity of water-soluble duocarmycin B1 prodrugs

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 20, 1999, Pages 2995-2998

  Asai, Akira ^a   Nagamura, Satoru ^a   Kobayashi, Eiji ^a   Gomi, Katsushige ^a   Saito, Hiromitsu ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMIC ACID DERIVATIVE; DUOCARMYCIN B1; GLYCOSIDE; METHYLPIPERAZINYLCARBAMOYL DERIVATIVE; PHOSPHATE; PRODRUG; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHILICITY; MOUSE; NONHUMAN;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; MICE; PRODRUGS; PYRROLIDINONES; SOLUBILITY; TUMOR CELLS, CULTURED; WATER;

EID: 0033581567     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00518-1     Document Type: Article

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