A general rule for the relationship between hydrophobic effect and conformational stability of a protein: Stability and structure of a series of hydrophobic mutants of human lysozyme

Journal of Molecular Biology

Volumn 280, Issue 4, 1998, Pages 749-761

  Takano, Kazufumi ^a   Yamagata, Yuriko ^a   Yutani, Katsuhide ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Disulfide bond; Double mutant; Human lysozyme; Hydrophobic effect; Protein stability

Indexed keywords

ALANINE; CYSTEINE; ISOLEUCINE; LYSOZYME; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISULFIDE BOND; ENTHALPY; HUMAN; HYDROPHOBICITY; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

EID: 0032563127     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.1906     Document Type: Article

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