From substrate to transition state analogues: The first potent inhibitor of sialyltransferases

Angewandte Chemie - International Edition

Volumn 38, Issue 10, 1999, Pages 1379-1380

  Schröder, Peer Nils ^a   Giannis, Athanassios ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

Enzyme inhibitors; Neuraminic acids; Rational design; Sialyltransferases; Transition state analogues

Indexed keywords

4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID ETHYL ESTER; CYTIDINE DIPHOSPHATE; CYTIDINE PHOSPHATE N ACETYLNEURAMINIC ACID; GLYCOCONJUGATE; N ACETYLNEURAMINIC ACID; N ACETYLNEURAMINIC ACID DERIVATIVE; SIALIC ACID; SIALYLTRANSFERASE; TRANSFERASE INHIBITOR; ZANAMIVIR;

ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; PHASE TRANSITION;

EID: 0033577905     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19990517)38:10<1379::AID-ANIE1379>3.0.CO;2-M     Document Type: Article

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