Effect of side chain location in (2-aminoethyl)aminomethyl-2- phenylquinolines as antitumor agents

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 10, 1998, Pages 1243-1248

  Mikata, Yuji ^a   Yokoyama, Mika ^a   Ogura, Shun ichiro ^b   Okura, Ichiro ^b   Kawasaki, Masafumi ^c   Maeda, Mizuo ^c   Yano, Shigenobu ^a  

^a NARA WOMEN'S UNIVERSITY   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Acridines; Antitumour compds; DNA; Polycyclic heterocyclic compds

Indexed keywords

(2 AMINOETHYL)AMINOMETHYL 2 PHENYLQUINOLINE; 2 PHENYLQUINOLINE DERIVATIVE; ACRIDINE DERIVATIVE; ANTINEOPLASTIC AGENT; CISPLATIN; DNA TOPOISOMERASE; HETEROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DENATURATION; DRUG DNA BINDING; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; INTERCALATION COMPLEX; SOLID TUMOR; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CELL SURVIVAL; DNA; DNA, SUPERHELICAL; DRUG DESIGN; HELA CELLS; HUMANS; INDICATORS AND REAGENTS; MOLECULAR STRUCTURE; NUCLEIC ACID DENATURATION; QUINOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032546503     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00192-9     Document Type: Article

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