Reversal of Regioselection in the Sharpless Asymmetric Aminohydroxylation of Aryl Ester Substrates

Organic Letters

Volumn 1, Issue 12, 1999, Pages 1949-1952

  Morgan, Adam J ^a   Masse, Craig E ^a   Panek, James S ^a  

^a BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AMINO ACID; ANTIINFECTIVE AGENT; DRUG DERIVATIVE; LACTACYSTIN; LACTAM; LIGAND;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATION; STEREOISOMERISM; SYNTHESIS;

ACETYLCYSTEINE; AMINO ACIDS; ANTI-BACTERIAL AGENTS; LACTAMS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STEREOISOMERISM;

EID: 0033576420     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol9903032     Document Type: Article

References (24)

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18. For the preparation of olefins 2a - i and 4a - d, see the Supporting Information.
19. 2 - PHAL as the ligand. The AA reaction afforded the α-hydroxy-β-amino ester as the major regiosiomeric product (ratio = 2.5:1). (Matrix Presented)
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22. 4 to be ca. 3.0 Å.
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