Molecular basis for enantioselectivity of lipase from Pseudomonas cepacia toward primary alcohols. Modeling, kinetics, and chemical modification of Tyr29 to increase or decrease enantioselectivity

Journal of Organic Chemistry

Volumn 64, Issue 8, 1999, Pages 2638-2647

  Tuomi, W Victor ^a   Kazlauskas, Romas J ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID ESTER; ALCOHOL DERIVATIVE; METHYL GROUP; N ACETYLIMIDAZOLE; PROPANOL; TETRANITROMETHANE; TRIACYLGLYCEROL LIPASE; TYROSINE DERIVATIVE;

ACETYLATION; ARTICLE; BURKHOLDERIA CEPACIA; CHEMICAL MODIFICATION; COMPUTER MODEL; ENANTIOMER; ENZYME CONFORMATION; ENZYME KINETICS; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR MODEL; NONHUMAN; STEREOCHEMISTRY;

EID: 0033574606     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo981783y     Document Type: Article

References (64)

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