Dizocilpine attenuates streptomycin-induced vestibulotoxicity in rats

Neuroscience Letters

Volumn 265, Issue 2, 1999, Pages 71-74

  Basile, Anthony S ^a   Brichta, Alan M ^b   Harris, Bradley D ^a   Morse, David ^a   Coling, Don ^c   Skolnick, Phil ^d  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

Behavior; Dizocilpine; Hair cells; Rat; Streptomycin; Vestibular organ

Indexed keywords

DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; STREPTOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; HAIR CELL; MALE; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; OPEN FIELD BEHAVIOR; OTOTOXICITY; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANTI-BACTERIAL AGENTS; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; HAIR CELLS; MALE; MICROSCOPY, ELECTRON, SCANNING; RATS; RATS, SPRAGUE-DAWLEY; STREPTOMYCIN; VESTIBULE;

EID: 0033574517     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00050-6     Document Type: Article

References (18)

1. Basile A.S., Huang J.M., Xie C., Webster D., Berlin C., Skolnick P. N-Methyl-D-aspartate antagonists limit aminoglycoside-induced ototoxicity. Nat. Med. 2:1996;1338-1343.
2. Begg E.J., Barclay M.L. Aminoglycosides - 50 years on. Br. J. Clin. Pharmacol. 39:1995;597-603.
3. Benveniste M., Mayer M.L. Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurons. J. Physiol. (Lond.). 464:1993;131-163.
4. Chandler P., Pennington M., Maccecchini M., Nashed N., Skolnick P. Polyamine-like actions of peptides derived from conantokin-G, an N-methyl-D-aspartate (NMDA) antagonist. J. Biol. Chem. 268:1993;17173-17178.
5. Choi D.W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
6. Dememes D., Wenthold R.J., Moniot B., Sans A. Glutamate-like immunoreactivity in the peripheral vestibular system of mammals. Hear. Res. 46:1990;261-269.
7. Duvall A.J., Wersall J. Site of action of streptomycin upon inner ear sensory cell. Acta Otolaryngol. 57:1964;581-598.
8. Gerhardt S.C., Boast C.A. Motor activity changes following cerebral ischemia in gerbils are correlated with the degree of neuronal degeneration in hippocampus. Behav. Neurosci. 102:1988;301-303.
9. Hawkins J.E., Preston R.E. Vestibular Ototoxicity. Naunton R.F. The Vestibular System. 1975;321 Academic Press, New York.
10. Kelley R.O., Dekker R.A., Bluemink J.G. Ligand mediated osmium binding: its application in coating biological specimens for scanning electron microscopy. J. Ultrastruct. Res. 45:1973;254-258.
11. Moser V.C., McCormick J.P., Creason J.P., MacPhail R.C. Comparison of chlordimeform and carbaryl using a functional observational battery. Fundam. Appl. Toxicol. 11:1988;189-206.
12. Niedzielski A.S., Wenthold R.J. Expression of AMPA, kainate, and NMDA receptor subunits in cochlear and vestibular ganglia. J. Neurosci. 15:1995;2338-2353.
13. Pullan L.M., Stumpo R.J., Powel R.J., Paschetto K.A., Britt M. Neomycin is an agonist at a polyamine site on the N-methyl-D-aspartate receptor. J. Neurochem. 59:1992;2087-2093.
14. Romano C., Williams K. Modulation of NMDA receptors by polyamines. Carter C. The Neuropharmacology of Polyamines. 1994;81 Academic Press, London.
15. Schaeppi U., Krinke G., FitzGerald R.E., Classen W. Impaired tunnel-maze behavior in rats with sensory lesions: vestibular and auditory systems. Neurotoxicology. 12:1991;445-454.
16. Smith P.F., de Waele C., Vidal P.P., Darlington C.L. Excitatory amino acid receptors in normal and abnormal vestibular function. Mol. Neurobiol. 5:1991;369-387.
17. Stringer S.P., Meyerhoff W.L., Wright C.G. Ototoxicity. Paparella M.M., Shumrick D.A., Gluckman J.L., Meyerhoff W.L. Otolaryngology. 1991;1653 W.B. Saunders, Philadelphia, PA.
18. Zhang L., Zheng X., Paupard M.C., Wang A.P., Santchi L., Friedman L.K., Zukin R.S., Bennett M.V.L. Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition. Proc. Natl. Acad. Sci. USA. 91:1994;10883-10887.