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Volumn 18, Issue 24, 1999, Pages 6908-6916

The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate

Author keywords

Intein; Metal ion footprinting; Phosphorothioates; Photocross linking

Indexed keywords

ENDONUCLEASE; OLIGODEOXYNUCLEOTIDE;

EID: 0033573087     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.24.6908     Document Type: Article
Times cited : (42)

References (43)
  • 1
    • 0027536144 scopus 로고
    • Restriction endonucleases and modification methylases
    • Anderson, J.E. (1993) Restriction endonucleases and modification methylases. Curr. Opin. Struct. Biol., 3, 24-30.
    • (1993) Curr. Opin. Struct. Biol. , vol.3 , pp. 24-30
    • Anderson, J.E.1
  • 2
    • 0029616336 scopus 로고
    • Mechanisms of intron mobility
    • Belfort, M. and Perlman, P.S. (1995) Mechanisms of intron mobility. J. Biol. Chem., 270, 30237-30240.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30237-30240
    • Belfort, M.1    Perlman, P.S.2
  • 3
    • 0030812487 scopus 로고    scopus 로고
    • Homing endonucleases: Keeping the house in order
    • Belfort, M. and Roberts, R.J. (1997) Homing endonucleases: keeping the house in order. Nucleic Acids Res., 25, 3379-3388.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3379-3388
    • Belfort, M.1    Roberts, R.J.2
  • 5
    • 0021765921 scopus 로고
    • Synthesis and characterization of an octanucleotide containing the EcoR1 recognition sequence with a phosphorothioate group at the cleavage site
    • Connolly, B.A., Potter, B.V, Eckstein F., Pingoud, A. and Grotjahn, L. (1984) Synthesis and characterization of an octanucleotide containing the EcoR1 recognition sequence with a phosphorothioate group at the cleavage site. Biochemistry, 23, 3443-3453.
    • (1984) Biochemistry , vol.23 , pp. 3443-3453
    • Connolly, B.A.1    Potter, B.V.2    Eckstein, F.3    Pingoud, A.4    Grotjahn, L.5
  • 6
    • 0029116947 scopus 로고
    • Protein splicing: Self-splicing of genetically mobile elements at the protein level
    • Cooper, A.A. and Stevens, T.H. (1995) Protein splicing: self-splicing of genetically mobile elements at the protein level. Trends Biochem. Sci., 20, 351-356.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 351-356
    • Cooper, A.A.1    Stevens, T.H.2
  • 7
    • 0030729344 scopus 로고    scopus 로고
    • Statistical modeling and analysis of the LAGLIDADG family of site-specific endonucleases and identification of an intein that encodes a site-specific endonuclease of the HNH family
    • Dalgaard, J.Z., Klar, A.J., Moser, M.J., Holley, W.R., Chatterjee, A. and Mian, I.S. (1997) Statistical modeling and analysis of the LAGLIDADG family of site-specific endonucleases and identification of an intein that encodes a site-specific endonuclease of the HNH family. Nucleic Acids Res., 25, 4626-4638.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4626-4638
    • Dalgaard, J.Z.1    Klar, A.J.2    Moser, M.J.3    Holley, W.R.4    Chatterjee, A.5    Mian, I.S.6
  • 8
    • 0030611387 scopus 로고    scopus 로고
    • Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity
    • Duan, X., Gimble, F.S. and Quiocho, F.A. (1997) Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity. Cell, 89, 555-564.
    • (1997) Cell , vol.89 , pp. 555-564
    • Duan, X.1    Gimble, F.S.2    Quiocho, F.A.3
  • 9
    • 0024446859 scopus 로고
    • Group I introns as mobile genetic elements: Facts and mechanistic speculations - A review
    • Dujon, B. (1989) Group I introns as mobile genetic elements: facts and mechanistic speculations - a review. Gene, 82, 91-114.
    • (1989) Gene , vol.82 , pp. 91-114
    • Dujon, B.1
  • 11
    • 0023030789 scopus 로고
    • Sequence of a peptide susceptible to mixed-function oxidation. Probable cation binding site in glutamine synthetase
    • Farber, J.M. and Levine, R.L. (1986) Sequence of a peptide susceptible to mixed-function oxidation. Probable cation binding site in glutamine synthetase. J. Biol. Chem., 261, 4574-4578.
    • (1986) J. Biol. Chem. , vol.261 , pp. 4574-4578
    • Farber, J.M.1    Levine, R.L.2
  • 12
    • 0032193937 scopus 로고    scopus 로고
    • Putting protein splicing to work
    • Gimble, F.S. (1998) Putting protein splicing to work. Curr. Biol., 5, 251-256.
    • (1998) Curr. Biol. , vol.5 , pp. 251-256
    • Gimble, F.S.1
  • 13
    • 0028947630 scopus 로고
    • Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease
    • Gimble, F.S. and Stephens, B.W. (1995) Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease. J. Biol. Chem., 270. 5849-5856.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5849-5856
    • Gimble, F.S.1    Stephens, B.W.2
  • 14
    • 0026772764 scopus 로고
    • Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae
    • Gimble, F.S. and Thorner, J. (1992) Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature, 357, 301-306.
    • (1992) Nature , vol.357 , pp. 301-306
    • Gimble, F.S.1    Thorner, J.2
  • 15
    • 0027375105 scopus 로고
    • Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae
    • Gimble, F.S. and Thorner, J. (1993) Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. J. Biol. Chem., 268, 21844-21853.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21844-21853
    • Gimble, F.S.1    Thorner, J.2
  • 16
    • 0030601890 scopus 로고    scopus 로고
    • Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing
    • Gimble, F.S. and Wang, J. (1996) Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing. J. Mol. Biol., 263, 163-180.
    • (1996) J. Mol. Biol. , vol.263 , pp. 163-180
    • Gimble, F.S.1    Wang, J.2
  • 17
    • 0032515167 scopus 로고    scopus 로고
    • Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center
    • Gimble, F.S., Duan, X., Hu, D. and Quiocho, F.A. (1998) Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center. J. Biol. Chem., 273, 30524-30529.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30524-30529
    • Gimble, F.S.1    Duan, X.2    Hu, D.3    Quiocho, F.A.4
  • 18
    • 0026687132 scopus 로고
    • Slereochemical outcome of the hydrolysis reaction catalyzed by the EcoRV restriction endonuclease
    • Grasby, J.A. and Connolly, B.A. (1992) Slereochemical outcome of the hydrolysis reaction catalyzed by the EcoRV restriction endonuclease. Biochemistry, 31, 7855-7861.
    • (1992) Biochemistry , vol.31 , pp. 7855-7861
    • Grasby, J.A.1    Connolly, B.A.2
  • 19
    • 0032522221 scopus 로고    scopus 로고
    • The protein splicing domain of the homing endonuclease PI-SceI is responsible for specific DNA binding
    • Grindl, W., Wende, W., Pingoud, V. and Pingoud, A. (1998) The protein splicing domain of the homing endonuclease PI-SceI is responsible for specific DNA binding. Nucleic Acids Res., 26, 1857-1862.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1857-1862
    • Grindl, W.1    Wende, W.2    Pingoud, V.3    Pingoud, A.4
  • 20
    • 0000560347 scopus 로고    scopus 로고
    • Amino acid residues in both the protein splicing and ndonuclease domains of the PI-SceI intein mediate DNA binding
    • He, Z., Crist, M. Yen, H., Duan, X., Quiocho, F.A. and Gimble, F.S. (1998) Amino acid residues in both the protein splicing and ndonuclease domains of the PI-SceI intein mediate DNA binding. J. Biol. Chem., 273, 4607-4615.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4607-4615
    • He, Z.1    Crist, M.2    Yen, H.3    Duan, X.4    Quiocho, F.A.5    Gimble, F.S.6
  • 21
    • 0030610426 scopus 로고    scopus 로고
    • The structure of I-CreI, a group I intron-encoded homing endonuclease
    • Heath, P.J., Stephens, K.M., Monnat, R.J. and Stoddard, B.L. (1997) The structure of I-CreI, a group I intron-encoded homing endonuclease. Nature Struct. Biol., 4, 468-476.
    • (1997) Nature Struct. Biol. , vol.4 , pp. 468-476
    • Heath, P.J.1    Stephens, K.M.2    Monnat, R.J.3    Stoddard, B.L.4
  • 22
    • 0021762388 scopus 로고
    • Cleavage of DNA with methidiumpropyl-EDTA-iron (II): Reaction conditions and product analysis
    • Hertzberg, R.P. and Dervan, P.B. (1984) Cleavage of DNA with methidiumpropyl-EDTA-iron (II): reaction conditions and product analysis. Biochemistry, 23, 3934-3945.
    • (1984) Biochemistry , vol.23 , pp. 3934-3945
    • Hertzberg, R.P.1    Dervan, P.B.2
  • 23
    • 0025914068 scopus 로고
    • A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction
    • Ito, W., Ishiguro, H. and Kurosawa, Y. (1991) A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction. Gene, 102, 67-70.
    • (1991) Gene , vol.102 , pp. 67-70
    • Ito, W.1    Ishiguro, H.2    Kurosawa, Y.3
  • 24
    • 0032185110 scopus 로고    scopus 로고
    • DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI
    • Jurica, M.S., Monnat, R.J., Jr and Stoddard, B.L. (1998) DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI. Mol. Cell, 2, 469-476.
    • (1998) Mol. Cell , vol.2 , pp. 469-476
    • Jurica, M.S.1    Monnat R.J., Jr.2    Stoddard, B.L.3
  • 25
    • 0027305131 scopus 로고
    • Introns as mobile genetic elements
    • Lambowitz, A.M. and Belfort, M. (1993) Introns as mobile genetic elements. Annu. Rev. Biochem., 62, 587-622.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 587-622
    • Lambowitz, A.M.1    Belfort, M.2
  • 26
    • 0029807336 scopus 로고    scopus 로고
    • Protein footprinting approach to mapping DNA binding sites of two archaeal homing enzymes: Evidence for a two-domain protein structure
    • Lykke-Andersen, J., Garrett, R.A. and Kjems, J. (1996) Protein footprinting approach to mapping DNA binding sites of two archaeal homing enzymes: evidence for a two-domain protein structure. Nucleic Acids Res., 24, 3982-3989.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 3982-3989
    • Lykke-Andersen, J.1    Garrett, R.A.2    Kjems, J.3
  • 27
    • 0030924866 scopus 로고    scopus 로고
    • Mapping metal ions at the catalytic centres of two intron-encoded endonucleases
    • Lykke-Andersen, J., Garrett, R.A. and Kjems, J. (1997) Mapping metal ions at the catalytic centres of two intron-encoded endonucleases. EMBO J., 16, 3272-3281.
    • (1997) EMBO J. , vol.16 , pp. 3272-3281
    • Lykke-Andersen, J.1    Garrett, R.A.2    Kjems, J.3
  • 28
    • 0033528762 scopus 로고    scopus 로고
    • A new method for determining the stereochemistry of DNA cleavage reactions: Application to the SfiI and HpaII restriction endonucleases and to the MuA transposase
    • Mizuuchi, K., Nobbs, T.J., Halford, S.E., Adzuma, K. and Qin, J. (1999) A new method for determining the stereochemistry of DNA cleavage reactions: application to the SfiI and HpaII restriction endonucleases and to the MuA transposase. Biochemistry, 38, 4640-4648.
    • (1999) Biochemistry , vol.38 , pp. 4640-4648
    • Mizuuchi, K.1    Nobbs, T.J.2    Halford, S.E.3    Adzuma, K.4    Qin, J.5
  • 29
    • 0001273526 scopus 로고
    • Homing endonucleases
    • Linn, S.M., Lloyd, R.S. and Roberts, R.J. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Mueller, J.E., Bryk, M., Loizos, N. and Belfort, M. (1993) Homing endonucleases. In Linn, S.M., Lloyd, R.S. and Roberts, R.J. (eds), Nucleuses. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 111-144.
    • (1993) Nucleuses , pp. 111-144
    • Mueller, J.E.1    Bryk, M.2    Loizos, N.3    Belfort, M.4
  • 30
    • 0032498234 scopus 로고    scopus 로고
    • Protein splicing of inteins and hedgehog autoproteolysis: Structure, function and evolution
    • Perler, F.B. (1998) Protein splicing of inteins and hedgehog autoproteolysis: structure, function and evolution. Cell, 92, 1-4.
    • (1998) Cell , vol.92 , pp. 1-4
    • Perler, F.B.1
  • 31
    • 0032474458 scopus 로고    scopus 로고
    • Structural and functional analysis of the homing endonuclease PI-SceI by limited proteolytic cleavage and molecular cloning of partial digestion products
    • Pingoud, V., Grindl, W., Wende, W., Thole, H. and Pingoud, A. (1998) Structural and functional analysis of the homing endonuclease PI-SceI by limited proteolytic cleavage and molecular cloning of partial digestion products. Biochemistry, 37, 8233-8243.
    • (1998) Biochemistry , vol.37 , pp. 8233-8243
    • Pingoud, V.1    Grindl, W.2    Wende, W.3    Thole, H.4    Pingoud, A.5
  • 32
    • 0033538004 scopus 로고    scopus 로고
    • Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence
    • Pingoud, V., Thole, H., Christ, F., Grindl, W., Wende, W. and Pingoud, A. (1999) Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence. J. Biol. Chem., 274, 10235-10243.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10235-10243
    • Pingoud, V.1    Thole, H.2    Christ, F.3    Grindl, W.4    Wende, W.5    Pingoud, A.6
  • 33
    • 0020536591 scopus 로고
    • Synthesis and configurational analysis of a dinucleoside phosphate isotopically chiral at phosphorus. Stereochemical course of Penicillium citrum nuclease P1 reaction
    • Potter, B.V., Connolly, B.A. and Eckstein, F. (1983) Synthesis and configurational analysis of a dinucleoside phosphate isotopically chiral at phosphorus. Stereochemical course of Penicillium citrum nuclease P1 reaction. Biochemistry, 22, 1369-1377.
    • (1983) Biochemistry , vol.22 , pp. 1369-1377
    • Potter, B.V.1    Connolly, B.A.2    Eckstein, F.3
  • 34
    • 0023020664 scopus 로고
    • Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region
    • Russell, D.W., Jensen, R., Zoller, M.J., Burke, J., Errede, B., Smith, M. and Herskowitz, I. (1986) Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region. Mol. Cell. Biol., 6, 4281-4294.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4281-4294
    • Russell, D.W.1    Jensen, R.2    Zoller, M.J.3    Burke, J.4    Errede, B.5    Smith, M.6    Herskowitz, I.7
  • 35
    • 0030777960 scopus 로고    scopus 로고
    • Genetic analysis of the Chlamydomonas reinhardtii I-CreI mobile intron homing system in Escherichia coli
    • Seligman, L.M., Stephens, K.M., Savage, J.H. and Monnat, R.J., Jr (1997) Genetic analysis of the Chlamydomonas reinhardtii I-CreI mobile intron homing system in Escherichia coli. Genetics, 147, 1653-1664.
    • (1997) Genetics , vol.147 , pp. 1653-1664
    • Seligman, L.M.1    Stephens, K.M.2    Savage, J.H.3    Monnat R.J., Jr.4
  • 36
    • 0029124041 scopus 로고
    • Protein splicing: Characterization of the aminosuccinimide residue at the carboxyl terminus of the excised intervening sequence
    • Shao, Y., Xu, M.-Q. and Paulus, H. (1995) Protein splicing: characterization of the aminosuccinimide residue at the carboxyl terminus of the excised intervening sequence. Biochemistry, 34, 10844-10850.
    • (1995) Biochemistry , vol.34 , pp. 10844-10850
    • Shao, Y.1    Xu, M.-Q.2    Paulus, H.3
  • 37
    • 0033525669 scopus 로고    scopus 로고
    • Crystal structure of the thermostable archaeal intron-encoded endonuclease I-DmoI
    • Silva, G.H., Dalgaard, J.Z., Belfort, M. and Van Roey, P. (1999) Crystal structure of the thermostable archaeal intron-encoded endonuclease I-DmoI. J. Mol. Biol. 286, 1123-1136.
    • (1999) J. Mol. Biol. , vol.286 , pp. 1123-1136
    • Silva, G.H.1    Dalgaard, J.Z.2    Belfort, M.3    Van Roey, P.4
  • 38
    • 33748719327 scopus 로고
    • Mechanisms of bleomycin-induced DNA degradation
    • Stubbe, J. and Kozarich, J.W. (1987) Mechanisms of bleomycin-induced DNA degradation. Chem. Rev., 87, 1107-1136.
    • (1987) Chem. Rev. , vol.87 , pp. 1107-1136
    • Stubbe, J.1    Kozarich, J.W.2
  • 39
    • 0025819774 scopus 로고
    • Site-directed mutagenesis studies with EcoRV restriction endonuclease to identify regions involved in recognition and catalysis
    • Thielking, V., Selent, U., Köhler, E., Wolfes, H., Pieper, U., Geiger, R., Urbanke, C., Winkler, F.K. and Pingoud, A. (1991) Site-directed mutagenesis studies with EcoRV restriction endonuclease to identify regions involved in recognition and catalysis. Biochemistry, 30, 6416-6422.
    • (1991) Biochemistry , vol.30 , pp. 6416-6422
    • Thielking, V.1    Selent, U.2    Köhler, E.3    Wolfes, H.4    Pieper, U.5    Geiger, R.6    Urbanke, C.7    Winkler, F.K.8    Pingoud, A.9
  • 40
    • 0025758730 scopus 로고
    • Internucleotide phosphite sulfurization with tetraethylthiuram disulfid phosphorothioate oligonucleotide synthesis via phosphoramidite chemistry
    • Vu, H. and Hirschbein, B.L. (1991) Internucleotide phosphite sulfurization with tetraethylthiuram disulfid phosphorothioate oligonucleotide synthesis via phosphoramidite chemistry. Tetrahedron Lett., 32, 3005-3008.
    • (1991) Tetrahedron Lett. , vol.32 , pp. 3005-3008
    • Vu, H.1    Hirschbein, B.L.2
  • 42
    • 0029860860 scopus 로고    scopus 로고
    • Binding, bending and cleavage of DNA substrates by the horning endonuclease PI-SceI
    • Wende, W., Grindl, W., Christ, F., Pingoud, A. and Pingoud, V. (1996) Binding, bending and cleavage of DNA substrates by the horning endonuclease PI-SceI. Nucleic Acids Res., 24, 4123-4132.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4123-4132
    • Wende, W.1    Grindl, W.2    Christ, F.3    Pingoud, A.4    Pingoud, V.5
  • 43
    • 9344221087 scopus 로고    scopus 로고
    • Mapping of catalytic residues in the RNA polymerase active centet
    • Zaychikov, E. et al. (1996) Mapping of catalytic residues in the RNA polymerase active centet Science, 273, 107-109.
    • (1996) Science , vol.273 , pp. 107-109
    • Zaychikov, E.1


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