Comparison of effects of two polymorphic variants of manganese superoxide dismutase on human breast MCF-7 cancer cell phenotype

Cancer Research

Volumn 59, Issue 24, 1999, Pages 6276-6283

  Zhang, Hannah J ^a   Yan, Tao ^a   Oberley, Terry D ^b   Oberley, Larry W ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE;

AMINO ACID COMPOSITION; ARTICLE; BREAST CANCER; CANCER INHIBITION; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; DNA POLYMORPHISM; GENE ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ALLELES; ANIMALS; BREAST NEOPLASMS; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PHENOTYPE; POLYMORPHISM, GENETIC; SUPEROXIDE DISMUTASE; TERMINOLOGY; TUMOR CELLS, CULTURED;

EID: 0033572554     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Burdon, R. H. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radical Biol. Med., 18: 775-794; 1995.
2. Chance, B., Sies, H., and Boveris, A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev., 59: 527-605; 1979.
3. Emerit, L. Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis, Free Radical Biol. Med., 16: 99-109, 1994.
4. Lebovitz, R. L., Zhang, H., Vogel, H., Cartwright, J., Jr., Dionne, L., Lu, N., Huang, S., and Matzuk, M. M. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc. Natl. Acad. Sci. USA, 93: 9782-9787, 1996.
5. Seo, H. G.; Takata, I., Nakamura, M., Tatsumi, H., Suzuki, K., Jujii, J., and Taniguchi, N. Induction of nitric oxide synthase and concomitant suppression of superoxide dismutase in experimental colitis in rats. Arch. Biochem. Biophys., 324: 41-47, 1995.
6. Zweier, J. L., Flaherty, J. T., and Weisfeldt, M. L. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc. Natl. Acad. Sci. USA, 84: 1404-1407, 1987.
7. Nath, N., Chari, S. N., and Rathi, A. B. Superoxide dismutase in diabetic polymorphonuclear leukocytes. Diabetes. 33: 586-589, 1984.
8. Beckman, K. B., and Ames, B. N. The free radical theory of aging matures. Physiol Rev, 78: 547-581, 1998.
9. Guyton, K. Z., and Kensler, T. W. Oxidative mechanism in carcinogenesis. Br. Med. Bull., 49: 523-544, 1993.
10. Oberley, L. W., and Buetlner, G. R. Role of superoxide dismutase in cancer: a review. Cancer Res., 39: 1141-1149, 1979.
11. Oberley, L. W., and Oberley, T. D. Free radicals, cancer and aging. In: J. E. Johnson, Jr., R. Walford, D. Harmon, and J. Miquel, (eds.), Free Radicals, Aging, and Degenerative diseases, pp. 352-377. New York: Alan R. Liss, 1986.
12. Church, S., Grant, J. W., Ridnour, L. A., Oberley, L. W., and Swanson, P. E. Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc. Natl. Acad. Sci. USA, 90: 3113-3117, 1993.
13. Li, J. J., Oberley, L. W., St. Clair, D. K., Ridnour, L. A., and Oberley, T. D. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. Oncogene, 10: 1989-2000, 1995.
14. Liu, R., Oberley, T. D., and Oberley, L. W. Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma. Hum. Gene Ther., 8: 585-595, 1997.
15. Yan, T., Oberley, L. W., Zhong, W., and St. Clair, D. K. Manganese-containing superoxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts. Cancer Res., 56: 2864-2871, 1996.
16. Zhong, W., Oberley, L. W., Oberley, T. D., and St. Clair, D. K. Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase. Oncogene, 14: 481-490, 1997.
17. Ambrosone, C. B., Freudenheim, J. L., Thompson, P. A., Bowman, E., Vena, J. E., Marshall, J. R., Graham, S., Laughlin, R., Nemoto, T., and Shields, P. G. Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res., 59: 602-606, 1999.
18. Ho, Y. S., and Crapo, J. D. Isolation and characterization of complementary DNAs encoding human manganese-containing superoxide dismutase. FEBS Lett., 299: 256-260, 1988.
19. 58Thr reduces activity by destabilizing the tetrameric interface. Biochemistry, 35: 4287-4297, 1996.
20. Oberley, L. W., McCormick, M. L., Sierra, E., and St. Clair, D. K. Manganese superoxide dismutase in normal and transformed human embryonic lung fibroblasts. Free Radical Biol. Med., 6: 379-384, 1989.
21. St. Clair, D. K., Wan, X. S., Oberley, T. D., Muse, K. E., and St. Clair, W. H. Suppression of radiation-induced neoplastic transformation by overexpression of mitochondrial superoxide dismutase. Mol. Carcinog., 6: 238-242, 1992.
22. Spitz, D. R., and Oberley, L. W. An assay for superoxide dismutase activity in mammalian tissue homogenates. Anal. Biochem., 179: 8-18, 1989.
23. Beauchamp, C., and Fridovich, I. Superoxide dismutase: improved assays and assay applicable to polyacrylamide gels. Anal. Biochem., 44: 276-287, 1971.
24. 2 radicals in 'autoimmune' diabetes. Immunol. Cell Biol., 67: 85-87, 1989.
25. Shimoda-Matsubayasbi, S., Matsumine, H., Kabayashi, T., Nakagawa-Hattori, Y., Shimizu, Y., and Mizuno, Y. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: a predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem. Biophys. Res. Commun., 226: 561-565, 1996.
26. Sun, Y. Free radicals, antioxidant enzymes, and carcinogenesis. Free Radical Biol. Med., 8: 583-599, 1990.
27. Miquel, J. An update on the mitochondrial-DNA mutation hypothesis of cell aging. Mutat. Res., 275: 209-216, 1992.
28. Miquel, J., Economos, A. C., Fleming, J., and Johnson, J. J. Mitochondrial role in cell aging. Exp. Geronlol., 15: 575-591, 1980.
29. Bize, I. B., Oberley, L. W., and Morris, H. P. Superoxide dismutase and superoxide radical in the Morris hepatomas. Cancer Res., 40: 3686-3693, 1980
30. Fernandez-Pol, J. A., Hamilton, P. D., and Kols, D. J. Correlation between the loss of the transformed phenotype and an increase in superoxide dismutase activity in a revertant subelone of sarcoma virus-infected mammalian cells. Cancer Res., 42: 609-617, 1982.
31. Marlhens, F., Nicole, A., and Sinet, P. M. Lowered level of translatable messenger RNAs for manganese superoxide dismutase in human fibroblasts transformed by SV40. Biochem. Biophys. Res. Commun., 129: 300-305, 1985.
32. McCormick, M. L., Oberley, T. D., Elwell, J. H., Oberley L. W., Sun Y., and Li, J. J. Superoxide dismutase and catalase levels during estrogen-induced renal tumorigenesis, in renal tumors and their autonomous variants in the Syrian hamster. Carcinogenesis (Lond.). 12: 977-983, 1991.
33. St. Clair, D. K., Oberley, T. D., Muse, K. E., and St. Clair, W. H. Expression of manganese superoxide dismutase promotes cellular differentiation. Free Radical Biol. Med., 16: 275-282, 1994.
34. Safford, S. E., Oberley, T. D., Urano, M., and St. Clair, D. K. Suppression of fibrosarcoma metastasis by elevated expression of manganese superoxide dismutase. Cancer Res., 54: 4261-4265, 1994.
35. Bravard, A., Sabatier, L., Hoffschir, F., Ricoul, M., Luccioni, C., and Dutrillaux, B. SOD2: a new type of tumor-suppressor gene? Int. J. Cancer. 51: 476-480, 1992.