Dicationic 2-fluorenonylcarbapenems: Potent anti-MRS agents with improved solubility and pharmacokinetic properties

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 22, 1999, Pages 3225-3230

  Greenlee, Mark L ^a   Laub, Joanne B ^a   Rouen, Gregory P ^a   DiNinno, Frank ^a   Hammond, Milton L ^a   Huber, Joann L ^a   Sundelof, Jon G ^a   Hammond, Gail G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAPENEM DERIVATIVE; CATION; IMIPENEM; L 695256; L 741462; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL MODEL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; HYDROPHILICITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUSE; NONHUMAN; PARTIAL DRUG SYNTHESIS; RHESUS MONKEY; SOLUBILITY; STRUCTURE ACTIVITY RELATION;

ANIMALIA; MACACA MULATTA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 0033571039     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00567-3     Document Type: Article

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