Effects of anti-PM-Scl 100 (Rrp6p exonuclease) antibodies on prenucleolar body dynamics at the end of mitosis

Experimental Cell Research

Volumn 251, Issue 2, 1999, Pages 452-464

  Fomproix, N ^a   Hernandez Verdun, D ^a  

^a INSTITUT JACQUES MONOD   (France)

Author keywords

Microinjection; Mitosis; Nucleoli; Nucleologenesis; Perichromosomal proteins; PM Scl complex; Prenucleolar body; PtK1 cells; Rrp6p exonuclease

Indexed keywords

CHROMOSOME PROTEIN; EXONUCLEASE; FIBRILLARIN; NUCLEAR PROTEIN; NUCLEOLIN; NUCLEOPHOSMIN; RNA 5.8S;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MICROINJECTION; MITOSIS; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TRANSPORT; RNA PROCESSING; WESTERN BLOTTING;

ANIMALIA;

EID: 0033568319     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1999.4578     Document Type: Article

References (58)

1. Briggs M. W., Burkard K. T. D., Butler J. S. Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3′ end formation. J. Biol. Chem. 273:1998;13255-13263.
2. Gottesfeld J. M., Forbes D. J. Mitotic repression of the transcriptional machinery. Trends Biochem. Sci. 22:1997;197-202.
3. Sollner-Webb B., Mougey E. B. News from the nucleolus: rRNA gene expression. Trends Biochem. Sci. 16:1991;58-62.
4. Gilbert N., Lucas L., Klein C., Ménager M., Bonnet N., Ploton D. Three-dimensional co-location of RNA polymerase I and DNA during interphase and mitosis by confocal microscopy. J. Cell Sci. 108:1995;115-125.
5. Haaf T., Reimer G., Schmid M. Immunocytogenetics: Localization of transcriptionally active rRNA genes in nucleoli and nucleolus organizer regions by use of human autoantibodies to RNA polymerase I. Cytogenet. Cell Genet. 48:1988;35-42.
6. Scheer U., Rose K. M. Localisation of RNA polymerase I in interphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry. Proc. Natl. Acad. Sci. USA. 81:1984;1431-1435.
7. Guldner H. H., Szostecki C., Vosberg H. P., Lakomek H. J., Penner E. Scl 70 autoantibodies from scleroderma patients recognize a 95 kDa protein identified as DNA topoisomerase I. Chromosoma. 94:1986;132-138.
8. Chan E. K. L., Imai H., Hamel J. C. Human autoantibody to RNA polymerase I transcription factor hUBF: Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor. J. Exp. Med. 174:1991;1239-1244.
9. Rendon M. C., Rodrigo R. M., Goenechea L. G., Garcia-Herdugo G., Valdivia M. M., Moreno F. J. Characterization and immunolocalization of nucleolar antigen with anti-NOR serum in HeLa cells. Exp. Cell Res. 200:1992;393-403.
10. Zatsepina O. V., Voit R., Grummt I., Spring H., Semenov M. V., Trendelenburg M. F. The RNA polymerase I-specific transcription initiation factor UBF is associated with transcriptionally active and inactive ribosomal genes. Chromosoma. 102:1993;599-611.
11. Roussel P., André C., Masson C., Géraud G., Hernandez-Verdun D. Localization of the RNA polymerase I transcription factor hUBF during the cell cycle. J. Cell Sci. 104:1993;327-337.
12. Jordan P., Mannervik M., Tora L., Carmofonseca M. In vivo evidence that TATA-binding protein SL1 colocalizes with UBF and RNA polymerase I when rRNA synthesis is either active or inactive. J. Cell Biol. 133:1996;225-234.
13. Roussel P., André C., Comai L., Hernandez-Verdun D. The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs. J. Cell Biol. 133:1996;235-246.
14. Schmidt-Zachmann M., Hügle B., Scheer U., Franke W. W. Identification and localization of a novel nucleolar protein of high molecular weight by a monoclonal antibody. Exp. Cell Res. 153:1984;327-346.
15. Jiménez-Garcia L. F., Segura-Valdez M. d. L., Ochs R. L., Rothblum L. I., Hannan R., Spector D. L. Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active Pre-rRNA transcription after mitosis. Mol. Biol. Cell. 5:1994;955-966.
16. Pai C. Y., Chen H. K., Sheu H. L., Yeh N. H. Cell cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis. J. Cell Sci. 108:1995;1911-1920.
17. Gautier T., Dauphin-Villemant C., André C., Masson C., Arnoult J., Hernandez-Verdun D. Identification and characterization of a new set of nucleolar ribonucleoproteins which line the chromosomes during mitosis. Exp. Cell Res. 200:1992;5-15.
18. Gautier T., Masson C., Quintana C., Arnoult J., Hernandez-Verdun D. The ultrastructure of the chromosome periphery in human cells: An in situ study using cryomethods in electron microscopy. Chromosoma. 101:1992;502-510.
19. Yasuda Y., Maul G. G. A nucleolar auto-antigen is part of a major chromosomal surface component. Chromosoma. 99:1990;152-160.
20. Luji S., Zumei N., Shi Z., GE W., Yang Y. Involvement of a nucleolar component, perichromonucleolin, in the condensation and decondensation of chromosomes. Proc. Natl. Acad. Sci. USA. 84:1987;7953-7956.
21. Ochs R., Lischwe M., O'Leary P., Bush H. Localization of nucleolar phosphoproteins B23 and C23 during mitosis. Exp. Cell Res. 146:1983;139-149.
22. Schmidt-Zachmann M. S., Hügle-Dörr B., Franke W. W. A constitutive nucleolar protein identified as a member of the nucleoplasmin family. EMBO J. 6:1987;1881-1890.
23. Medina F. J., Cerdido A., Fernandez-Gomez M. C. Components of nucleolar processing complex (pre-rRNA, fibrillarin, and nucleolin) colocalize during mitosis and are incorporated to daughter cell nucleoli. Exp. Cell Res. 221:1995;11-125.
24. Weisenberger D., Scheer U. A possible mechanism for the inhibition of ribosomal RNA gene transcription during mitosis. J. Cell Biol. 129:1995;561-575.
25. Verheijen R., Kuijpers H. J. H., Schlingemann R. O., Boehmer A. L. M., Van Driel R., Brakenhoff G. J., Ramaekers F. C. S. Ki-67 detects a nuclear matrix-associated proliferation-related antigen I: Intra cellular localization during interphase. J. Cell Sci. 92:1989;123-130.
26. Gautier T., Fomproix N., Masson C., Azum-Gélade M. C., Gas N., Hernandez-Verdun D. Fate of specific nucleolar perichromosomal proteins during mitosis: Cellular distribution and association with U3 snoRNA. Biol. Cell. 82:1994;81-93.
27. Hernandez-Verdun D., Gautier T. The chromosome periphery during mitosis. BioEssays. 16:1994;179-185.
28. Gautier T., Robert-Nicoud M., Guilly M.-N., Hernandez-Verdun D. Relocation of nucleolar proteins around chromosomes at mitosis - A study by confocal laser scanning microscopy. J. Cell Sci. 102:1992;729-737.
29. Gébrane-Younès J., Fomproix N., Hernandez-Verdun D. When rDNA transcription is arrested during mitosis, UBF is still associated with noncondensed rDNA. J. Cell Sci. 110:1997;2429-2440.
30. Schubert I., Dolezel J., Houben A., Scherthan H., Wanner G. Refined examination of plant metaphase chromosome structure at different levels made feasible by new isolation methods. Chromosoma. 102:1993;96-101.
31. Fomproix N., Gébrane-Younès J., Hernandez-Verdun D. Effect of anti-fibrillarin antibodies on building of functional nucleoli at the end of mitosis. J. Cell Sci. 111:1998;359-372.
32. Zatsepina O. V., Dudnic O. A., Todorov I. T., Thiry M., Spring H., Trendelenburg M. F. Experimental induction of prenucleolar bodies (PNBs) in interphase cells: Interphase PNBs show similar characteristics as those typically observed at telophase of mitosis in untreated cells. Chromosoma. 105:1997;418-430.
33. Ochs R. L., Lischwe M. A., Shen E., Carroll R. E., Busch H. Nucleologenesis: Composition and fate of prenucleolar bodies. Chromosoma. 92:1985;330-336.
34. Ochs R. L., Lischwe M. A., Spohn W. H., Busch H. Fibrillarin: A new protein of the nucleolus identified by autoimmune sera. Biol. Cell. 54:1985;123-134.
35. Gas N., Escande M. L., Stevens B. J. Immunolocalization of the 100 kDa nucleolar protein during the mitotic cycle in CHO cells. Biol. Cell. 53:1985;209-218.
36. Jiménez-Garcia L. F., Rothblum L. I., Busch H., Ochs R. L. Nucleologenesis: Use of non-isotopic in situ hybridization and immunocytochemistry to compare the localization of rDNA and nucleolar proteins during mitosis. Biol. Cell. 65:1989;239-246.
37. Reimer G., Scheer U., Peters J. M., Tan E. M. Immunolocalization and partial characterization of a nucleolar autoantigen (PM-Scl) associated with polymyositis/scleroderma overlap syndromes. J. Immunol. 137:1986;3802-3808.
38. Bell P., Scheer U. Prenucleolar bodies contain coilin and are assembled in Xenopus egg extract depleted of specific nucleolar proteins and U3 RNA. J. Cell Sci. 110:1997;43-54.
39. Beven A. F., Lee R., Razaz M., Leader D. J., Brown J. W. S., Shaw P. J. The organization of ribosomal RNA processing correlates with distribution of nucleolar snRNAs. J. Cell Sci. 109:1996;1241-1251.
40. Carmo-Fonseca M., Ferreira J., Lamond A. I. Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis - Evidence that the coiled body is a kinetic nuclear structure. J. Cell. Biol. 120:1993;841-852.
41. Alderuccio F., Chan E. K., Tan E. M. Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: A unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex. J. Exp. Med. 173:1991;941-952.
42. Blüthner M., Bautz F. A. Cloning and characterization of the cDNA coding for a polymyositis-scleroderma overlap syndrome-related nucleolar 100-kD protein. J. Exp. Med. 176:1992;973-980.
43. Ge Q., Wu Y., James J. A., Targoff I. N. Epitope analysis of the major reactive region of the 100-kd protein of PM-Scl autoantigen. Arthritis Rheum. 39:1996;1588-1595.
44. Blüthner M., Bautz E. K., Bautz F. A. Mapping of epitopes recognized by PM/Scl autoantibodies with gene-fragment phage display libraries. J. Immunol. Methods. 198:1996;187-198.
45. Ge Q., Frank M. B., O'Brien C., Targoff I. N. Cloning of a complementary DNA coding for the 100-kD antigenic protein of the PM-Scl autoantigen. J. Clin. Invest. 90:1992;559-570.
46. Gelpi C., Alguero A., Angeles-Martinez M., Vidal S., Juarez C., Rodriguez-Sanchez J. L. Identification of protein components reactive with anti-PM/Scl autoantibodies. Clin. Exp. Immunol. 81:1990;59-64.
47. Robert-Fortel I., Junéra H. R., Géraud G., Hernandez-Verdun D. Three-dimensional organization of the ribosomal genes and Ag-NOR proteins during interphase and mitosis in PtK1 cells studied by confocal microscopy. Chromosoma. 102:1993;146-157.
48. Reimer G., Pollard K. M., Pennig C. A., Ochs R. L., Lischwe M. A., Busch H., Tan E. M. Monoclonal autoantibody from NZB/NZW F1 mouse and some human scleroderma sera target a Mr 34000 nucleolar protein of the U3-ribonucleoprotein particle. Arthritis Rheum. 30:1987;793-800.
49. Hernandez-Verdun D., Prévot S., André C., Guilly M. N., Masson C., Wolfe J. Autoimmune serum containing an antibody against a 94 kDa nucleolar protein. Biol. Cell. 64:1988;331-341.
50. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
51. Escande M.-L., Gas N., Stevens B. J. Immunolocalization of the 100 K nucleolar protein in CHO cells. Biol. Cell. 53:1985;99-110.
52. Targoff I. N., Reichlin M. Nucleolar localization of the PM-Scl antigen. Arthritis Rheum. 28:1985;226-230.
53. Mitchell P., Petfalski E., Shevchenko A., Mann M., Tollervey D. The exosome: A conserved eukaryotic RNA processing complex containing multiple 3′-5′ exoribonucleases. Cell. 1997:1997;457-466.
54. Tollervey D. Trans-acting factors in ribosome synthesis. Exp. Cell Res. 229:1996;226-232.
55. Mitchell P., Petfalski E., Tollervey D. The 3′ end of the yeast 5.8 rRNA is generated by an exonuclease processing mechanism. Genes Dev. 10:1996;502-513.
56. Hadjiolov A. A. The Nucleolus and Ribosome Biogenesis. 1985;Springer-Verlag, Vienna, New York. p. 1-268.
57. r 40,000 protein specific to precursor particles of the large ribosomal subunit. Cell. 41:1985;615-627.
58. Savkur R. S., Olson M. O. J. Preferential cleavage in preribosomal RNA by protein B23 endoribonuclease. Nucleic Acids Res. 26:1998;4508-4515.