Kinetic studies on drug-resistant variants of Escherichia coli thymidylate synthase: Functional effects of amino acid substitutions at residue 4

Archives of Biochemistry and Biophysics

Volumn 368, Issue 2, 1999, Pages 257-264

  Mahdavian, Elahe ^a   Spencer, H Trent ^a   Dunlap, R Bruce ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DEOXYURIDINE PHOSPHATE; FLOXURIDINE; FLOXURIDINE PHOSPHATE; METHYLENETETRAHYDROFOLIC ACID; THYMIDYLATE SYNTHASE;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG RESISTANCE; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; EXPRESSION VECTOR; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 0033567218     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1999.1319     Document Type: Article

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