Separate roles for H-Ras and Rac in signaling by transforming growth factor (TGF)-β: H-Ras is essential for activation of MAP kinase, partially required for transcriptional activation by TGF-β, but not required for signaling of growth suppression by TGF-β

European Journal of Biochemistry

Volumn 264, Issue 1, 1999, Pages 110-119

  Yamamoto, Hiroaki ^a   Atsuchi, Nobuhiko ^a   Tanaka, Haruki ^a   Ogawa, Wataru ^b   Abe, Mayumi ^c   Takeshita, Akira ^a   Ueno, Hikaru ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

Growth factor; MAP kinase; Signal transduction; Transcription

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; EXPRESSION VECTOR; GROWTH INHIBITION; IMMUNOBLOTTING; NONHUMAN; ONCOGENE; ONCOGENE H RAS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ADENOVIRIDAE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELL LINE; ENZYME ACTIVATION; GTP-BINDING PROTEINS; MINK; ONCOGENE PROTEIN P21(RAS); RAC GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; MUSTELA VISON;

EID: 0033567160     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00584.x     Document Type: Article

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