Crystal structure of plant aspartic proteinase prophytepsin: Inactivation and vacuolar targeting

EMBO Journal

Volumn 18, Issue 14, 1999, Pages 3947-3955

  Kervinen, Jukka ^a,d   Tobin, Gregory J ^b   Costa, Júlia ^c   Waugh, David S ^a   Wlodawer, Alexander ^a   Zdanov, Alexander ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c Inst Biol Exp Tecnologica I   (Portugal)

^d FOX CHASE CANCER CENTER   (United States)

Author keywords

Aspartic proteinases; Phytepsin; Saposin like domain; Transport to vacuoles; Zymogen structure

Indexed keywords

ASPARTIC PROTEINASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BARLEY; BINDING SITE; CRYSTAL STRUCTURE; ENZYME INACTIVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ASPARTIC ENDOPEPTIDASES; BIOLOGICAL TRANSPORT; CATHEPSINS; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; ELECTRONS; ENZYME ACTIVATION; ENZYME PRECURSORS; GLYCOPROTEINS; GOLGI APPARATUS; HORDEUM; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEOLIPIDS; PULMONARY SURFACTANTS; RECEPTORS, CELL SURFACE; SAPOSINS; SEQUENCE HOMOLOGY, AMINO ACID; VACUOLES;

EID: 0033565640     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.14.3947     Document Type: Article

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