Fine chemical manipulations of microscopic liquid samples. 1. Droplet loading with chemicals

Analytical Chemistry

Volumn 71, Issue 14, 1999, Pages 2751-2756

  Gratzl, Miklós ^a,b   Lu, Hongwen ^b   Matsumoto, Takashi ^a   Yi, Chen ^a   Bright, Gary R ^c  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE;

ADSORPTION; ARTICLE; CHEMICAL ANALYSIS; DIFFUSION; MICROMANIPULATION; PHASE SEPARATION; WATER SAMPLING;

CHEMISTRY, ANALYTICAL;

EID: 0033565482     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac980929q     Document Type: Article

References (13)

1. Yi, C.; Bright, G. R.; Gratzl, M. BMES Fall meeting, Salt Lake City, UT, 1992; Abstract A4.5.
2. Gratzl, M.; Yi, C. Anal. Chem. 1993, 65, 2085-2088.
3. Yi, C.; Gratzl, M. Anal. Chem. 1994, 66, 1976-1982.
4. Yi, C.; Huang, D.; Gratzl, M. Anal. Chem. 1996, 68, 1580-1584.
5. Lu, H.; Gratzl, M. Optical detection in microscopic domains. 1. Monitoring chemical manipulations with absorption microspectrometry. Anal. Chem., in press.
6. Kashyap, R.; Gratzl, M. Anal. Chem. 1998, 70, 1468-1476.
7. Yao, H.; Ikeda, H.; Inoue, Y.; Kitamura, N. Anal. Chem. 1996, 68, 4304-4307.
8. Chiu, D. T.; Hsiao, A.; Gaggar, A.; Garza-Lopez, R. A.; Orwar, O.; Zare, R. N. Anal. Chem. 1997, 69, 1801-1807.
9. Bright, G. R.; Yi, C.; Gratzl, M. Delivery of molecules into single cells with a Difusional Microburet. Biophys. J. Submitted.
10. Lu, H.; Gratzl, M. Delivery of doxorubicin into single multidrug resistant cancer cells with a diffusional microburet. Biophys. J. Manuscript to be submitted.
11. Yi, C.; Saidel, J.; Gratzl, M. Single cell model for simultaneous drug delivery and efflux. Ann. Biomed. Eng., in press.
12. Lu, H.; Gratzl, M. Adsorption of doxorubicin onto the aqueous/heptane interface of microscopic liquid particles assessed with a DMB and confocal microscopy. J. Phys. Chem. Manuscript to be submitted.
13. Yi, C. Development of a diffusional microtitration device and a carbon fiber microsensor for drug influx/efflux studies on single cancer cells. Ph.D. Thesis, Case Western Reserve University, 1995.